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Author: Alain P. Foucault Publisher: CRC Press ISBN: 9780824792572 Category : Science Languages : en Pages : 432
Book Description
This volume in the Chromatographic Science series introduces centrifugal partition chromatography (CPC) for any biphasic system, offering thorough coverage of instrumentation, theory, liquid-liquid partition co-efficients and CPC in organic and inorganic chemistry. Over 80 diagrams for three-solvent systems that can be applied to virtually all partitioning, separation and purification situations, are contained.
Author: Alain P. Foucault Publisher: CRC Press ISBN: 9780824792572 Category : Science Languages : en Pages : 432
Book Description
This volume in the Chromatographic Science series introduces centrifugal partition chromatography (CPC) for any biphasic system, offering thorough coverage of instrumentation, theory, liquid-liquid partition co-efficients and CPC in organic and inorganic chemistry. Over 80 diagrams for three-solvent systems that can be applied to virtually all partitioning, separation and purification situations, are contained.
Author: Jean-Michel Menet Publisher: CRC Press ISBN: 9780824799922 Category : Science Languages : en Pages : 302
Book Description
Covering definitions, concepts, and applications, Countercurrent Chromatography recounts the developments in two types of liquid-liquid chromatography termed countercurrent-high-speed countercurrent chromatography (HSCCC) and centrifugal partition chromatography (CPC)-as well as the HSCCC-derived cross-axis CCC, a versatile technique for purification in biotechnology applications. The text investigates mechanisms for mixing liquid phases, particularly hydrostatic techniques for CPC and hydrodynamic for coil planet centrifuges. It also explores the use of countercurrent chromatography in inorganic analysis, chiral separation, and the separation of natural products.
Author: K. Hostettmann Publisher: Springer Science & Business Media ISBN: 3662036312 Category : Science Languages : en Pages : 259
Book Description
Over the past few years, increasing attention has been paid to the search for bioactive compounds from natural sources. The success of plant-derived products such as paclitaxel (Taxol) in tumor therapy or artemisinin in the treatment of malaria has provided the impetus for the introduction of numerous research programmes, especially in Industry. A great deal of effort is being expended in the generation of novel lead molecules of vegetable, marine and microbial origin by the use of high throughput screening protocols. When interesting hits are found, it is essen tial to have methods available for the rapid isolation of target compounds. For this reason, both industry and academia need efficient preparative chromatographic separation techniques and experience in their application. Purified natural products are required for complete spectro scopic identification and full characterization of new compo unds, for biological testing and for the supply of pharmaceuti cals, standards, and starting materials for synthetic work. Obtaining pure products from an extract can be a very long, te dious and expensive undertaking, involving many steps. Sometimes only minute amounts of the desired compounds are at hand and these entities may be labile. Thus it is an advantage to have access to as many different methods as possible in order to aid the isolation process. Although a certain amount of trial and error may be involved, nowadays there is the possibility of devising suitable rapid separation schemes by a judicious choice of the different techniques available.
Author: Mohammad Reza Ganjali Publisher: Elsevier ISBN: 0124200958 Category : Science Languages : en Pages : 450
Book Description
Lanthanides Series Determination by Various Analytical Methods describes the different spectroscopic and electrochemical methods used for the determination and measurement of lanthanides. Numerous examples of determination methods used in real sample analysis are gathered and explained, and the importance of lanthanides as applied in chemical industry, agriculture, clinical and pharmaceutical industry, and biology is discussed, with many applications and recent advantages given. - Written by world-leading experts in research on lanthanide determination - Discusses determination methods that range from very advanced and expensive techniques to simple and inexpensive methods - A single source of information for a broad collection of lanthanide detection techniques and applications - Includes a complete list of reports and patents on lanthanide determination - Discusses both advantages and disadvantages of each determination method, giving a well-balanced overview
Author: Andrzej Gorak Publisher: Royal Society of Chemistry ISBN: 1788010329 Category : Science Languages : en Pages : 544
Book Description
The first book dedicated entirely to this area, Intensification of Biobased Processes provides a comprehensive overview of modern process intensification technologies used in bioprocessing.
Author: A. Berthod Publisher: ISBN: Category : Medical Languages : en Pages : 432
Book Description
Countercurrent chromatography (CCC) is a separation technique in which the stationary phase is a liquid. The mobile phase is also a liquid, so biphasic liquid systems with at least two solvents are used. Centrifugal fields are used to hold the liquid stationary phase while pushing the liquid mobile phase through it. This comprehensive reference covers recent advancements in the two types of CCC machines: the high speed CCCs without rotary seals and with coiled spools and centrifugal partition chromatographs (CPC) with rotary seals and interconnected channels. Written by leading international experts in the CCC field, the book focuses on the liquid nature of the stationary phase: giving newcomers the basis to do CCC efficiently and rapidly; explaining the art of obtaining a biphasic liquid system; describing the flow patterns in both CPC and high speed CCC machines; showing possible other uses of a liquid stationary phase; presenting a wealth of applications in the separation of organic, pharmaceutical and inorganic mixtures; and demonstrating that even supercritical fluids can be used in CCC.
Author: William H. Streng Publisher: Springer Science & Business Media ISBN: 1461513456 Category : Science Languages : en Pages : 282
Book Description
Scientists from many disciplines require making observations which are dependent upon the behavior of compounds in solution. This ranges from areas in geography, such as oceanography, to areas in chemistry, such as chromatography, to areas in biology, such as pharmacology. Historically, information would be obtained by observing a response for a given set of conditions and then the conditions would be changed and a new response obtained. In this approach there would be little effort made to actually understand how a compound was behaving in solution but rather just the response was noted. Understanding the behavior of compounds in solution is critical to understanding their behavior in biological systems. This has become increasingly important during the last twenty years as an understanding of the biochemistry related to human illness has become better understood. The development of the pharmaceutical industry and the need to rapidly screen large numbers of compounds has made scientists in the area of drug development aware that the pharmacological activity of compounds can be predicted by knowing their solution physical chemical properties. This is not to say that a specific drug-active site interaction can be predicted but rather a prediction can be made whether or not a compound will be absorbed, transported, or distributed within a physiological system in such a way that an interaction can occur.
Author: Beatrice E. Bachmeier Publisher: MDPI ISBN: 3039214497 Category : Medical Languages : en Pages : 274
Book Description
The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.
Author: Alirio Rodrigues Publisher: Butterworth-Heinemann ISBN: 0128020512 Category : Technology & Engineering Languages : en Pages : 305
Book Description
Simulated Moving Bed Technology is one of only a few books solely dedicated to SMB. It aims to equip you with the tools and skills needed for SMB modelling, simulation, design and operation. The theory presented is supported by real-world examples from the petrochemical, sugar and pharma industries.The core of the book focuses on SMB process development and model validation. It explains basic process concepts and definitions, fundamental principles and equations, as well as typical applications and recent advances made to address challenges. Its specialist content makes it a must have book for people working with SMB technology, chemical engineering post-graduate students and process and R&D engineers in industry. - Will provide you with the tools and predictive approaches for use in SMB design and performance assessment - Covers SMB modelling, simulation, design and operation as applied to separation and reaction processes - Discusses process intensification through coupling SMB and reaction in SMBR, membrane permeation and SMBR in PermSMBR and introduces the design of SCPC
Author: Alain P. Foucault
Author: Alain P. Foucault
Author: Jean-Michel Menet
Author: K. Hostettmann
Author: Mohammad Reza Ganjali
Author: Andrzej Gorak
Author: A. Berthod
Author: Walter D. Conway
Author: William H. Streng
Author: Beatrice E. Bachmeier
Author: Alirio Rodrigues