Cellule stromale mesenchymateuse et thérapie cellulaire en odontologie PDF Download

Author: Alicja Lipiec
Publisher:
ISBN:
Category :
Languages : fr
Pages : 202

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Book Description
La recherche sur l'utilisation des cellules souches a suscité ces dernières années un grand intérêt en médecine régénérative et notamment en odontologie. Les cellules stromales mésenchymateuses adultes, en particulier grâce à leurs propriétés d'immuno-modulation et de différenciation, apparaissent comme de bonnes candidates pour les stratégies régénératives de la cavité orale (régénération pulpaire, parodontale, osseuse...). La littérature nous éclaire sur de nombreux protocoles de thérapie cellulaire en odontologie dont l'utilisation potentielle en clinique représente un vrai défi pour les chercheurs et un grand espoir pour les patients.

Author: Charlotte Vaillant
Publisher:
ISBN:
Category :
Languages : fr
Pages : 160

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Book Description
L'utilisation des cellules stromales mésenchymateuses issues des dents temporaires exfoliées (SHED) en médecine régénérative pourrait permettre non plus de réparer mais de régénérer certaines structures tissulaires lésées. Les dents temporaires constituent une source accessible de cellules multipotentes post-natales dont les propriétés sont exploitables en thérapie cellulaire et ingénierie tissulaire. Les champs d'investigation s'élargissent depuis la découverte des SHED, notamment en régénération des tissus oro-faciaux, neurologie, cardiologie, pneumologie, hépatologie, immunologie. Elles peuvent être prélevées aisément et cryoconservées pendant plusieurs années en conservant leur viabilité. Cependant, en France, le stockage des SHED à titre préventif au sein de biobanques privées en vue de leur utilisation potentielle ultérieure autologue reste à ce jour interdit.

Author: Hervé Emonard
Publisher: Frontiers Media SA
ISBN: 2889450244
Category :
Languages : en
Pages : 131

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The invasive character of a primary cancer is greatly dependent on numerous interactions between tumor cells and their extracellular surroundings. Matricellular receptors are defined as (cell-surface) receptors that bind extracellular matrix (ECM) structural proteins and soluble factors dynamically acting on ECM homeostasis. Matricellular receptors mediate numerous signalings from the extracellular environment to cell nucleus and drive main biological functions that are cell growth, survival and migration. Numerous data from the last decade evidence that matricellular receptors are biosensors that allow to a tumor cell answering to microenvironmental variations, and in this sense they are important contributors to tumor cell malignancy. Matricellular receptors represent thus valuable targets for the development of original anti-cancer strategies. Original reports, bibliographic reviews or hypotheses are welcome to improve the basic knowledge of matricellular receptor properties, their spatio-temporal regulation, the dynamic formation of complex receptors and the impact of such interactions on the invasive properties of tumor cells. Biological, biophysical and pharmacological, as well as in silico contributions will be appreciated.

Author: Alain Reinberg
Publisher: CRC Press
ISBN:
Category : Design
Languages : en
Pages : 268

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Book Description
Periodical and predictable changes in biological susceptibility and response to a large variety of chemical agents, including drugs and food, have been documented since the early 1970s. This book provides a survey of clinically-documented research in chronopharmacology.

Author: Sue Blattes
Publisher: L'Editeur : EDP Sciences
ISBN: 9782868835888
Category : English language
Languages : fr
Pages : 264

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Book Description
Cet ouvrage, devenu célèbre sous son sigle MCSE, a déjà été utilisé par plus de 50 000 étudiants, chercheurs, professionnels. L'objectif est de lire et écrire des textes en anglais scientifique avec facilité et pertinence. L'ouvrage est conçu pour que l'apprenant devienne un véritable utilisateur de l'anglais. La méthode originale repose sur l'analyse des fonctions et structures nécessaires : measurement, frequency, comparison, modification, link words, time, cause and consequence, hypothesis, modality, purpose and process, impersonal forms, compound nouns and adjectives. Dans chaque unit, des tests d'auto-évaluation permettent de se situer et de construire son parcours de formation, d'abord en définissant ses objectifs à l'aide des key points et du lexis, puis, de façon plus personnalisée, en puisant dans les examples in context, checkpoints (back to basics, word web), web search, FAQs... MCSE est l'outil de base d'une méthode qui comprend aussi d'autres outils dans la même collection (Listening Comprehension for Scientiflc English et Speaking Skills in Scientitic English). L'ouvrage est destiné à tout apprenant de niveau baccalauréat qui désire acquérir une réelle compétence dans l'écriture et la lecture de textes en anglais scientifique.

Author: A. Sollberger
Publisher:
ISBN:
Category : Biological rhythms
Languages : en
Pages : 472

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Author: Jacques Lafontaine
Publisher: Springer
ISBN: 3319207350
Category : Mathematics
Languages : en
Pages : 408

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Book Description
This book is an introduction to differential manifolds. It gives solid preliminaries for more advanced topics: Riemannian manifolds, differential topology, Lie theory. It presupposes little background: the reader is only expected to master basic differential calculus, and a little point-set topology. The book covers the main topics of differential geometry: manifolds, tangent space, vector fields, differential forms, Lie groups, and a few more sophisticated topics such as de Rham cohomology, degree theory and the Gauss-Bonnet theorem for surfaces. Its ambition is to give solid foundations. In particular, the introduction of “abstract” notions such as manifolds or differential forms is motivated via questions and examples from mathematics or theoretical physics. More than 150 exercises, some of them easy and classical, some others more sophisticated, will help the beginner as well as the more expert reader. Solutions are provided for most of them. The book should be of interest to various readers: undergraduate and graduate students for a first contact to differential manifolds, mathematicians from other fields and physicists who wish to acquire some feeling about this beautiful theory. The original French text Introduction aux variétés différentielles has been a best-seller in its category in France for many years. Jacques Lafontaine was successively assistant Professor at Paris Diderot University and Professor at the University of Montpellier, where he is presently emeritus. His main research interests are Riemannian and pseudo-Riemannian geometry, including some aspects of mathematical relativity. Besides his personal research articles, he was involved in several textbooks and research monographs.

Author: Dorothy T. Krieger
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 352

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Author:
Publisher:
ISBN: 9789393682246
Category :
Languages : en
Pages : 0

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Author: Lars A. Akslen
Publisher:
ISBN: 9783030989514
Category :
Languages : en
Pages : 0

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This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.