Cell Colonization Control by Physical and Chemical Modification of Materials PDF Download

Author: L. Baeakova
Publisher:
ISBN: 9781607414087
Category : Biomedical materials
Languages : en
Pages : 88

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Book Description

Author: Daiki Kimura
Publisher: Nova Publishers
ISBN: 9781604561326
Category : Medical
Languages : en
Pages : 254

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Book Description
The basis for cell proliferation entails the control of key signalling and cell cycle regulators through transcriptional, translational, post-translational, genetic and epigenetic mechanisms. Many conceptual breakthroughs in cell regulation have derived from analyses of basic cell cycle mechanisms. This book presents research in the field.

Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description

Author: Swaminathan Sethuraman
Publisher: CRC Press
ISBN: 1315351951
Category : Medical
Languages : en
Pages : 306

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Book Description
Nanotechnology and high-end characterization techniques have highlighted the importance of the material choice for the success of tissue engineering. A paradigm shift has been seen from conventional passive materials as scaffolds to smart multi-functional materials that can mimic the complex intracellular milieu more effectively. This book presents a detailed overview of the rationale involved in the choice of materials for regeneration of different tissues and the future directions in this fascinating area of materials science with specific chapters on regulatory challenges & ethics; tissue engineered medical products.

Author: L. Baèáková
Publisher:
ISBN: 9781604568875
Category : Biomedical materials
Languages : en
Pages : 0

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Book Description
Cell-material interface plays a key role in the interaction of cells with artificial materials designed for construction of body implants or tissue engineering. Physical and chemical properties of the material surface, such as its polarity, wettability, electrical charge and conductivity, roughness and morphology, rigidity or elasticity as well as the presence of various chemical functional groups, strongly influence the cell adhesion. The latter is mediated by adsorption of cell adhesion-mediating molecules (eg: vitronectin, fibronectin, collagen, laminin, fibrinogen) from the serum of the culture medium or body fluids in appropriate spatial conformation or flexibility enabling the accessibility of specific sites on these molecules (eg: certain amino acid sequences or saccharide-based ligands) by adhesion receptors on the cell membrane (eg: integrins). After binding these ligands, the adhesion receptors are recruited into focal adhesion plaques, where they associate with cascades of various structural and signalling molecules, such as cytoskeletal proteins and kinases. By these cascades, the signal provided by the cell-material interaction is delivered to the cell nucleus. It influences the gene expression, and thus the further behavior of cells, manifested by their viability, synthesis of various molecules, proliferation, differentiation, functioning, immune activation, stress adaptation or cell death. This interdisciplinary review involves: (i) physical modifications of the material surface by plasma discharge, irradiation with ions or ultraviolet light and effects of these modifications on the surface wettability, electrical conductivity and formation of chemical functional groups influencing cell adhesion, (ii) deposition of organic or inorganic layers on the material surfaces, especially those nanostructured (eg: nanofibers of fibrin and extracellular matrix molecules, carbon nanoparticles, such as nanodiamonds, fullerenes and nanotubes, nanocomposite metal/C:H layers), (iii) functionalisation of the material surface with amino acids and oligopeptidic ligands for cell adhesion receptors (e.g., GRGDSG), (iv) effect of all these modifications on the extent and strength of adhesion of vascular and bone-derived cells, cell proliferation activity, switch between cell proliferation and differentiation, expression of cell-type specific markers of differentiation and other cell functions.

Author: Islam Khalil
Publisher: BoD – Books on Demand
ISBN: 1789858690
Category : Technology & Engineering
Languages : en
Pages : 144

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Book Description
Nanomedicine refers to the use of nanotechnological applications in biomedical fields such as therapeutics, diagnostics, monitoring, visualization, tissue engineering and even surgery. This book presents recent updates in the nanomedicine market and discusses several aspects of drug delivery and tissue regeneration using different platforms and devices.

Author: Zhong Lin Wang
Publisher: Springer
ISBN: 3319400398
Category : Technology & Engineering
Languages : en
Pages : 537

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Book Description
This book introduces an innovative and high-efficiency technology for mechanical energy harvesting. The book covers the history and development of triboelectric nanogenerators, basic structures, working principles, performance characterization, and potential applications. It is divided into three parts: Part A illustrates the fundamental working modes of triboelectric nanogenerators with their prototype structures and theoretical analysis; Part B and Part C introduce two categories of applications, namely self-powered systems and self-powered active sensors. The book will be an ideal guide to scientists and engineers beginning to study triboelectric nanogenerators or wishing to deepen their knowledge of the field. Readers will be able to place the technical details about this technology in context, and acquire the necessary skills to reproduce the experimental setups for fabrication and measurement.

Author: Alexandru Grumezescu
Publisher: William Andrew
ISBN: 0323428851
Category : Technology & Engineering
Languages : en
Pages : 512

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Book Description
Nanobiomaterials in Hard Tissue Engineering covers the latest developments in the field of hard tissue engineering at the nanoscale. Leading researchers from around the world discuss the latest research and offer new insights. This book presents data about the fabrication and characterization of nanobiomaterials involved in hard tissue reconstruction, describing recent progress and the advantages of both conventional and computer-aided methods. Recent applications of different classes of nanobiomaterials are discussed, with in vitro and in vivo applications also explained in detail. Special attention is paid to the applications of nanobiomaterials in bone regeneration and in the development of functional coatings for tailored implants to improve osseointegration. Finally, the book considers future challenges and perspectives. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. - An up-to-date and highly structured guide for researchers, practitioners and students working in biomedical, biotechnological and engineering fields - A detailed and invaluable overview of hard tissue engineering, an increasingly important field - Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Author: Michael Berger
Publisher: Royal Society of Chemistry
ISBN: 1847558836
Category : Science
Languages : en
Pages : 332

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Book Description
Each of the chapters is based on a particular scientific paper that has been published in a peer-reviewed journal and, while each story revolves around one or two scientists who were interviewed for this book, many, if not most, of the scientific accomplishments covered in the book are the result of collaborative efforts by several scientists and research groups, often from different organizations and from different countries. The book is different to other books in this field because it provides a novel human touch to nanotechnology research by not only covering a wide range of research topics but also the (often nameless) scientists behind this research. The book is a collection of Spotlight articles from the popular Nanowerk website and each article has been crafted with the author(s) of a scientific paper and signed off by them prior to being posted on Nanowerk.

Author: Ajit Behera
Publisher: CRC Press
ISBN: 1003848346
Category : Technology & Engineering
Languages : en
Pages : 641

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Book Description
Surface engineering provides one of the most important means of engineering product differentiation in terms of quality, performance, and lifecycle cost. It is essential to achieve predetermined functional properties of materials such as mechanical strength, biocompatibility, corrosion resistance, wear resistance, and heat and oxidation resistance. Surface Engineering of Biomaterials addresses this topic across a diverse range of process technologies and healthcare applications. Introduces biomaterial surface science and surface engineering and includes criteria for biomaterial surface selection Focuses on a broad array of materials including metals, ceramics, polymers, alloys, and composites Discusses corrosion, degradation, and material release issues in implant materials Covers various processing routes to develop biomaterial surfaces, including for smart and energy applications Details techniques for post-modification of biomaterial surfaces This reference work helps researchers working at the intersection of materials science and biotechnology to engineer functional biomaterials for a variety of applications.