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Hematologic Malignancies

Hematologic Malignancies PDF Author: Manorama Bhargava
Publisher: Springer Nature
ISBN: 9813347996
Category : Medical
Languages : en
Pages : 246

Book Description
This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.

Hematologic Malignancies

Hematologic Malignancies PDF Author: Manorama Bhargava
Publisher: Springer Nature
ISBN: 9813347996
Category : Medical
Languages : en
Pages : 246

Book Description
This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.

Case Studies in Hematologic Malignancies

Case Studies in Hematologic Malignancies PDF Author: Ronan Allen
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Book Description
Hematologic malignancies, also known as blood cancers, refer to a wide range of cancers that originate in the bone marrow or the lymphatic system. These cancers can affect the production and function of blood cells, including white blood cells, red blood cells and platelets. Hematologic malignancies include leukemia, lymphoma, and multiple myeloma. The treatment of hematologic malignancies depends on the specific type and stage of the cancer, as well as individual patient factors. These malignancies can be treated through radiation therapy, chemotherapy, immunotherapy, targeted therapy and stem cell transplantation. Radiation therapy uses high-energy radiation to target and kill cancer cells. Chemotherapy makes use of powerful medications to destroy cancer cells or prevent their growth. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of hematological malignancies. It will serve as a valuable source of reference for graduate and postgraduate students.

Williams Hematology, 10th Edition

Williams Hematology, 10th Edition PDF Author: Kenneth Kaushansky
Publisher: McGraw Hill Professional
ISBN: 126046413X
Category : Medical
Languages : en
Pages : 2705

Book Description
The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of basic science and translational pathophysiology for optimal, lifelong learning. Experts in research and clinical hematology, the editors are known worldwide for their contributions to the field. This new edition contains everything that has made Williams Hematology the go-to resource for decades and has been updated with new chapters and critical new research into the molecular mechanisms responsible for hematological disorders and the impact on diagnosis and treatment. And the new format enables you to access each chapter via content modules covering key topics, with summaries, infographics, and cases―all linked to review questions for self-assessment. The full-color presentation integrates images of blood and tissue findings where they are cited in the text. NEW TO THIS EDITION: Updated and revised content reflecting the latest research and developments Convenient format that streamlines the learning process and improves retention Additional chapters added on: Immune Checkpoint Inhibitors Immune Cell Therapy: Chimeric Antigen Receptor T Cell Therapy Immune Cell Therapy Dendritic Cell and Natural Killer Cell Therapy The processes of cell death and survival Application of Big Data and Deep Learning in Hematology Williams Hematology Cases with multiple-choice questions including detailed explanations—perfect preparation for the boards Continuously updated online content with comprehensive drug therapy database and other resources

Haematology Case Studies with Blood Cell Morphology and Pathophysiology

Haematology Case Studies with Blood Cell Morphology and Pathophysiology PDF Author: Indu Singh
Publisher: Academic Press
ISBN: 0128119489
Category : Medical
Languages : en
Pages : 276

Book Description
Hematology Case Studies with Blood Cell Morphology and Pathophysiology compiles specialized case studies with specific information on various hematological disorders with Full Blood Examination (FBE or CBC), blood film images and pathophysiology of each condition. In addition, it provides basic information on how to recognize and diagnose hematological conditions that are frequently observed in the laboratory. Technicians and scientists working in core laboratories such as biochemistry labs or blood banks will find this book to be extremely thorough. Moreover, it can be used as a reference book by technicians, scientists and hematologists in every level of expertise in diagnosing hematological disorders. Includes morphology of red cells, white cells and platelets Provides images of actual blood slides under the microscope, showing the most important diagnostic features observed in each condition Presents details that are considered difficult for beginners or non- hematologists, such as specific tests and techniques Covers case studies that finish with the pathophysiology of the condition

Hematology and Oncology Through Case Studies

Hematology and Oncology Through Case Studies PDF Author: Cairo Clarke
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Book Description
Hematology and oncology are closely related medical specialties that deal with the diagnosis, treatment, and management of blood disorders and cancer respectively. They are separate specialties, and they are combined for the treatment of hematologic malignancies. These malignancies refer to the cancers which originate in the blood forming tissue. Hematological malignancies are classified into three types, namely, multiple myeloma, leukemia and lymphoma. The cancer which develops in the bone marrow and affects plasma cells is known as multiple myeloma. Leukemia refers to a cancer that begins in the bone marrow or blood. On the other hand, lymphoma is a type of hematological malignancy which begins in a part of the immune system known as the lymphatic system. This book includes some of the vital pieces of works being conducted across the world, on various topics related to hematology and oncology. It presents researches and studies performed by experts across the globe. The book is appropriate for students seeking detailed information in this area of medicine as well as for experts.

Childhood Cancer and Functional Impacts Across the Care Continuum

Childhood Cancer and Functional Impacts Across the Care Continuum PDF Author: National Academies of Sciences Engineering and Medicine
Publisher:
ISBN: 9780309683494
Category :
Languages : en
Pages :

Book Description
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Case Studies in Hematology and Coagulation: A New Ascp Caseset

Case Studies in Hematology and Coagulation: A New Ascp Caseset PDF Author: Gene Ed Gulati
Publisher:
ISBN: 9780891895855
Category : Blood
Languages : en
Pages : 527

Book Description


Hematology Case Review

Hematology Case Review PDF Author: Donald C. Doll
Publisher: Lippincott Williams & Wilkins
ISBN: 1469852705
Category : Medical
Languages : en
Pages : 326

Book Description
Hematology Case Review is a comprehensive text that covers the expansive knowledge about the study of blood cells. After collecting blood smears and bone marrow aspirates for over 40 years, Dr. Doll has created the most up to date and comprehensive compilation of hematology case studies. These samples form the core of the case studies featured in this book, including benign disorders, such as hereditary spherocytosis, to neoplastic neoplasms like acute leukemia. Within the text, both rare and common conditions are discussed, with the presenting symptoms, blood counts, and pertinent images. The book is formatted in an interactive problem-based layout in order to enhance the question and answer features of the book. It is a widely applicable text that has been utilized for its practicality for over 15 years, and is becoming particularly important for general internists, family practice physicians, and hospitalists. Additionally, Hematology Case Review continues to be a vital tool and asset for medical students, medical residents, hematology-oncology fellows, and pathology residents.

Hematology Case Review

Hematology Case Review PDF Author: Donald C. Doll
Publisher: LWW
ISBN: 9781451191431
Category : Blood
Languages : en
Pages : 0

Book Description
Hematology Case Review is a comprehensive text that covers the expansive knowledge about the study of blood cells. After collecting blood smears and bone marrow aspirates for over 40 years, Dr. Doll has created the most up to date and comprehensive compilation of hematology case studies. These samples form the core of the case studies featured in this book, including benign disorders, such as hereditary spherocytosis, to neoplastic neoplasms like acute leukemia. Within the text, both rare and common conditions are discussed, with the presenting symptoms, blood counts, and pertinent images. The book is formatted in an interactive problem-based layout in order to enhance the question and answer features of the book. It is a widely applicable text that has been utilized for its practicality for over 15 years, and is becoming particularly important for general internists, family practice physicians, and hospitalists. Additionally, Hematology Case Review continues to be a vital tool and asset for medical students, medical residents, hematology-oncology fellows, and pathology residents. FEATURES: - 95 comprehensive case studies - 227 full-color images - Up-to-date information from hands-on clinical practice

Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease

Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309157277
Category : Medical
Languages : en
Pages : 335

Book Description
Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.