Author:
Publisher:
ISBN:
Category : Court calendars
Languages : en
Pages : 2790
Book Description
The Martindale-Hubbell Law Directory
Monthly Checklist of State Publications
Author: Library of Congress. Exchange and Gift Division
Publisher:
ISBN:
Category : State government publications
Languages : en
Pages : 1152
Book Description
June and Dec. issues contain listings of periodicals.
Publisher:
ISBN:
Category : State government publications
Languages : en
Pages : 1152
Book Description
June and Dec. issues contain listings of periodicals.
Membership Directory
Author: Federation of Genealogical Societies (U.S.)
Publisher:
ISBN:
Category : Genealogy
Languages : en
Pages : 262
Book Description
Publisher:
ISBN:
Category : Genealogy
Languages : en
Pages : 262
Book Description
Constitution and List of Members
Author: American Society of Civil Engineers
Publisher:
ISBN:
Category : Civil engineering
Languages : en
Pages : 394
Book Description
Publisher:
ISBN:
Category : Civil engineering
Languages : en
Pages : 394
Book Description
The American Catalogue
Fiftieth anniversary yearbook and list of active members of the National Educational Association
Author: National Education Association of the United States
Publisher:
ISBN:
Category : Education
Languages : en
Pages : 536
Book Description
Publisher:
ISBN:
Category : Education
Languages : en
Pages : 536
Book Description
Directory of Corporate Counsel
Author:
Publisher:
ISBN:
Category : Corporate legal departments
Languages : en
Pages : 1566
Book Description
Publisher:
ISBN:
Category : Corporate legal departments
Languages : en
Pages : 1566
Book Description
Decennial Digest of Indian Cases, 1901-10
Quinolone Antibacterials
Author: Jochen Kuhlmann
Publisher: Springer Science & Business Media
ISBN: 3642803644
Category : Medical
Languages : en
Pages : 505
Book Description
It has been over 30 years since the first clinically important member of the quinolone class, nalidixic acid, was introduced into medical practice. The modification produced in the quinolone nucleus by introducing a fluorine at the 6-position led to the discovery of the newer fluoroquinolones with enhanced antibacterial activities as compared to nalidixic acid. By now a great deal of preclinical and clinical experience has been obtained with these agents. The intense interest in this class of antibacterial agents by chemists, micro biologists, toxicologists, pharmacologists, clinical pharmacologists, and clini cians in various disciplines encouraged us to summarize the information on the history, chemistry, mode of action and in vitro properties, kinetics and efficacy in animals, mechanisms of resistance, toxicity, clinical pharmacology, clinical experience, and future prospects in one volume of the Handbook of Experimental Pharmacology. As this series deals predominantly with "experimental" characteristics of drugs, our volume is dedicated specifically to quinolones and emphasizes principally their preclinical and clinical phar macological characteristics, despite the existence of several summaries on quinolones. The chemistry of the quinolones is described in detail. The chapter on the mode of action of quinolones reports the conclusive evidence that gyrase is the intracellular target of the quinolones; however, another enzyme, topoisomerase IV, may also be a target for quinolones, and the exact mechanisms by which quinolones act bactericidally are far from being understood.
Publisher: Springer Science & Business Media
ISBN: 3642803644
Category : Medical
Languages : en
Pages : 505
Book Description
It has been over 30 years since the first clinically important member of the quinolone class, nalidixic acid, was introduced into medical practice. The modification produced in the quinolone nucleus by introducing a fluorine at the 6-position led to the discovery of the newer fluoroquinolones with enhanced antibacterial activities as compared to nalidixic acid. By now a great deal of preclinical and clinical experience has been obtained with these agents. The intense interest in this class of antibacterial agents by chemists, micro biologists, toxicologists, pharmacologists, clinical pharmacologists, and clini cians in various disciplines encouraged us to summarize the information on the history, chemistry, mode of action and in vitro properties, kinetics and efficacy in animals, mechanisms of resistance, toxicity, clinical pharmacology, clinical experience, and future prospects in one volume of the Handbook of Experimental Pharmacology. As this series deals predominantly with "experimental" characteristics of drugs, our volume is dedicated specifically to quinolones and emphasizes principally their preclinical and clinical phar macological characteristics, despite the existence of several summaries on quinolones. The chemistry of the quinolones is described in detail. The chapter on the mode of action of quinolones reports the conclusive evidence that gyrase is the intracellular target of the quinolones; however, another enzyme, topoisomerase IV, may also be a target for quinolones, and the exact mechanisms by which quinolones act bactericidally are far from being understood.
The Oxford Handbook of Philosophy of Emotion
Author: Peter Goldie
Publisher: Oxford University Press
ISBN: 0191572632
Category : Philosophy
Languages : en
Pages : 722
Book Description
This volume contains thirty-one state-of-the-art contributions from leading figures in the study of emotion today. The volume addresses all the central philosophical issues in current emotion research, including: the nature of emotion and of emotional life; the history of emotion from Plato to Sartre; emotion and practical reason; emotion and the self; emotion, value, and morality; and emotion, art and aesthetics. Anyone interested in the philosophy of emotion, and its wide-ranging implications in other related fields such as morality and aesthetics, will want to consult this book. It will be a vital resource not only for scholars and graduate students but also for undergraduates who are finding their way into this fascinating topic.
Publisher: Oxford University Press
ISBN: 0191572632
Category : Philosophy
Languages : en
Pages : 722
Book Description
This volume contains thirty-one state-of-the-art contributions from leading figures in the study of emotion today. The volume addresses all the central philosophical issues in current emotion research, including: the nature of emotion and of emotional life; the history of emotion from Plato to Sartre; emotion and practical reason; emotion and the self; emotion, value, and morality; and emotion, art and aesthetics. Anyone interested in the philosophy of emotion, and its wide-ranging implications in other related fields such as morality and aesthetics, will want to consult this book. It will be a vital resource not only for scholars and graduate students but also for undergraduates who are finding their way into this fascinating topic.