Cardiovascular Pharmacology of the Prostaglandins PDF Download

Author: A. G. Herman
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 480

View

Book Description

Author: Ryszard Gryglewski
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 344

View

Book Description
Ten years after the discovery of prostacyclin, our knowledge of its biochemical mode of action, pharmacological properties, pathophysiological significance and therapeutic applications is ever expanding. Prostacyclin is both complex and unique as demonstrated by its unusual feature of being chemically and meta bolically unstable when compared to other prostanoids and known amine or peptide mediators. Although physiologically essential, the chemical instability of prostacyclin poses a serious drawback in laboratory and clinical studies. It is one of the genuine objectives of pharmaceutical research to supply synthetic compounds which overcome the inherent drawbacks - considering investigational and therapeutic use - of endogenous compounds. Whereas metabolic instability in certain cases could be of advantage, chemical instability definitely is not. With Iloprost, a molecule has been designed which - according to all data so far available - pertains high receptor affinity, metabolic instability (clinically this equates with a fine control of Iloprost's effects) while chemical stability has been achieved. By virtue of these characteristics Iloprost can be considered as one step towards specific interaction within the arachidonic acid cascade, namely the prostacyclin receptor. The aim of the symposium was to provide a critical experimental appraisal concerning the biochemical mode of action and pharmacological properties of prostacyclin and Iloprost.

Author: Karsten Schrör
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 596

View

Book Description

Author: M. F. Cuthbert
Publisher: Elsevier
ISBN: 1483192806
Category : Medical
Languages : en
Pages : 345

View

Book Description
The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application. Chapters I to IV of this book deal with the chemistry and classification, distribution and metabolism, general pharmacology, and mechanism of action. The rest of the chapters discuss the relationship of the prostaglandins to the reproductive, cardiovascular, respiratory, and gastro-intestinal systems with an emphasis on the human pharmacology and potential therapeutic applications. This text also includes the speculations and suggestions of contributors regarding the possible and further use of the prostaglandins. This publication is a good reference for biochemists and medical students concerned with the potential of prostaglandins.

Author: Helmut Sinzinger
Publisher: Birkhauser
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 402

View

Book Description

Author: A. Scriabine
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 530

View

Book Description

Author: Stan Greenberg
Publisher: Marcel Dekker
ISBN:
Category : Medical
Languages : en
Pages : 488

View

Book Description

Author: Takayuki Ozawa
Publisher: Taylor & Francis Group
ISBN:
Category : Medical
Languages : en
Pages : 236

View

Book Description

Author: Colin Pinnock
Publisher: Cambridge University Press
ISBN: 9780521690799
Category : Medical
Languages : en
Pages : 990

View

Book Description
The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.

Author: John A. Oates
Publisher:
ISBN: 9780890045800
Category : Appareil cardiovasculaire
Languages : en
Pages : 388

View

Book Description