Cadmium-113 and Carbon-13 Nuclear Magnetic Resonance Study of Metalloproteins PDF Download

Author: Allen R. Palmer
Publisher:
ISBN:
Category : Organometallic compounds
Languages : en
Pages : 246

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Author:
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 1370

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Lists citations with abstracts for aerospace related reports obtained from world wide sources and announces documents that have recently been entered into the NASA Scientific and Technical Information Database.

Author: G A Webb
Publisher: Royal Society of Chemistry
ISBN: 1847553702
Category : Science
Languages : en
Pages : 436

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As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Acids" and "NMR of Carbohydrates, Lipids and Membranes". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an in valuable source of current methods and applications. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Author: Lawrence J. Berliner
Publisher: Springer Science & Business Media
ISBN: 1461565405
Category : Science
Languages : en
Pages : 356

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We take great pleasure in presenting Vol. IV of Biological Magnetic Resonance, a series that continues to give us pride. In this volume, we are pleased to have our first chapter on the applications of ESR to problems in medicine, written by Butterfield. Armitage and Otvos describe their extensive Cd-l13 NMR study in a chapter that should delight the spectroscopists as well as the biochemists, since the systems investigated have not yet been modeled. Kaptein presents an eloquent exposition of the principles and applications to biological systems of the photo-CIDNP technique, to which he has made pioneering contributions. Perkins tells everything one always wanted to know about the applications of ring current calculations in structural studies of biological macromolecules. Our philosophy has been, and continues to be, to present topics of current interest by authors who are active in their field, while maintaining the inter national flavor of the series. Ideally, the coverage of each topic should approach that found both in a textbook and in a reference book, rather than being a mere literature review. We are grateful to the authors for their cooperation in this respect. We continue to solicit the comments and suggestions of our readers and our colleagues, and thank those who have already responded, including the reviewers in the periodicals. Lawrence J. Berliner Jacques Reuben ix Contents Chapter 1 Spin Labeling in Disease D. Allan Butterfield 1. Introduction ...................................... . 2. Membrane Structure . . . . . . . . . . . . . . . . . . . . . . . . . . 2 . . . . . . . 2.1. General Principles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.2. The Erythrocyte Membrane. . . . . . . . . . . . . . . . . . . 4 . . . . .

Author:
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 1756

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Author: Hans J. Vogel
Publisher: Springer Science & Business Media
ISBN: 1592591841
Category : Science
Languages : en
Pages : 415

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Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so it modifies their biological activity or their stability. Because of its distinct che- cal properties calcium is uniquely suited to act as an on–off switch or as a light dimmer of biological activities. The two books entitled Calcium-Binding Protein Protocols (Volumes I and II) focus on modern experimental analyses and methodologies for the study of calcium-binding proteins. Both extracel- lar and intracellular calcium-binding proteins are discussed in detail. H- ever, proteins involved in calcium handling (e. g. , calcium pumps and calcium channels), fall outside of the scope of these two volumes. Also, calcium-bi- ing proteins involved in bone deposition will not be discussed, as this specific topic has been addressed previously. The focus of these two books is on studies of the calcium-binding proteins and their behavior in vitro and in vivo. The primary emphasis is on protein chemistry and biophysical methods. Many of the methods described will also be applicable to proteins that do not bind calcium. Calcium-Binding Protein Protocols is divided into three main sections. The section entitled Introduction and Reviews provides information on the role of calcium in intracellular secondary messenger activation mechanisms. Mo- over, unique aspects of calcium chemistry and the utilization of calcium in dairy proteins, as well as calcium-binding proteins involved in blood clotting, are addressed.

Author:
Publisher:
ISBN:
Category : Nuclear magnetic resonance
Languages : en
Pages : 576

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Author: J.B. Lambert
Publisher: Springer Science & Business Media
ISBN: 9789027715821
Category : Mathematics
Languages : en
Pages : 574

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The field of nuclear magnetic resonance has experienced a number of spectacular developments during the last decade. Fourier transform methodology revolutionized signal acquisition capabilities. Superconducting magnets enhanced sensitivity and produced considerable improvement in spectral dispersion. In areas of new applicat ions, the life sciences particularly bene fited from these developments and probably saw the largest increase in usage. NMR imaging promises to offer a noninvasive alternative to X rays. High resolution is now achievable with solids, through magic angle spinning and cross polarization, so that the powers of NMR are applicable to previously intractable materials such as polymers, coal, and other geochemicals. The ease of obtaining relaxation times brought an important fourth variable, after the chemical shift, the coupling constant, and the rate constant, to the examination of structural and kinetic problems i~ all fields. Software development, particularly in the area of pulse sequences, created a host of useful tech niques, including difference decoupling and difference nuclear Overhauser effect spectra, multidimensional displays, signal enhancement (INEPT), coupling constant analysis for connectivity (INADEQUATE), and observation of specific structural classes such as only quaternary carbons. Finally, hardware development gave us access to the entire Periodic Table, to the particular advan tage of the inorganic and organometallic chemist. At the NATO Advanced Study Institute at Stirling, Scotland, the participants endeavored to examine all these advances, except imaging, from a multidisciplinary point of view.

Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 826

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Author:
Publisher: Academic Press
ISBN: 0080922171
Category : Science
Languages : en
Pages : 7207

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The Second Edition of the Encyclopedia of Spectroscopy and Spectrometry pulls key information into a single source for quick access to answers and/or in-depth examination of topics. "SPEC-2" covers theory, methods, and applications for researchers, students, and professionals—combining proven techniques and new insights for comprehensive coverage of the field. The content is available in print and online via ScienceDirect, the latter of which offers optimal flexibility, accessibility, and usability through anytime, anywhere access for multiple users and superior search functionality. No other work gives analytical and physical (bio)chemists such unprecedented access to the literature. With 30% new content, SPEC-2 maintains the "authoritative, balanced coverage" of the original work while also breaking new ground in spectroscopic research. Incorporates more than 150 color figures, 5,000 references, and 300 articles (30% of which are new), for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Features a new co-editor: David Koppenaal of Pacific Northwest National Laboratory, Washington, USA, whose work in atomic mass spectrometry has been recognized internationally