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Bridging the COVID-19 Data and the Epidemiological Model Using Time Varying Parameter SIRD Model

Bridging the COVID-19 Data and the Epidemiological Model Using Time Varying Parameter SIRD Model PDF Author: Cem Çakmaklı
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description
This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized autoregressive score modelling structure designed for the typically daily count data related to pandemic. The resulting specification permits a flexible yet parsimonious model structure with a very low computational cost. This is especially crucial at the onset of the pandemic when the data is scarce and the uncertainty is abundant. Full sample results show that countries including US, Brazil and Russia are still not able to contain the pandemic with the US having the worst performance. Furthermore, Iran and South Korea are likely to experience the second wave of the pandemic. A real-time exercise show that the proposed structure delivers timely and precise information on the current stance of the pandemic ahead of the competitors that use rolling window. This, in turn, transforms into accurate short-term predictions of the active cases. We further modify the model to allow for unreported cases. Results suggest that the effects of the presence of these cases on the estimation results diminish towards the end of sample with the increasing number of testing.

Bridging the COVID-19 Data and the Epidemiological Model Using Time Varying Parameter SIRD Model

Bridging the COVID-19 Data and the Epidemiological Model Using Time Varying Parameter SIRD Model PDF Author: Cem Çakmaklı
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description
This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized autoregressive score modelling structure designed for the typically daily count data related to pandemic. The resulting specification permits a flexible yet parsimonious model structure with a very low computational cost. This is especially crucial at the onset of the pandemic when the data is scarce and the uncertainty is abundant. Full sample results show that countries including US, Brazil and Russia are still not able to contain the pandemic with the US having the worst performance. Furthermore, Iran and South Korea are likely to experience the second wave of the pandemic. A real-time exercise show that the proposed structure delivers timely and precise information on the current stance of the pandemic ahead of the competitors that use rolling window. This, in turn, transforms into accurate short-term predictions of the active cases. We further modify the model to allow for unreported cases. Results suggest that the effects of the presence of these cases on the estimation results diminish towards the end of sample with the increasing number of testing.

Estimating and Simulating a SIRD Model of COVID-19 for Many Countries, States, and Cities

Estimating and Simulating a SIRD Model of COVID-19 for Many Countries, States, and Cities PDF Author: Jesús Fernández-Villaverde
Publisher:
ISBN:
Category : COVID-19 (Disease)
Languages : en
Pages : 43

Book Description
We use data on deaths in New York City, Madrid, Stockholm, and other world cities as well as in various U.S. states and various countries and regions to estimate a standard epidemiological model of COVID-19. We allow for a time-varying contact rate in order to capture behavioral and policy-induced changes associated with social distancing. We simulate the model forward to consider possible futures for various countries, states, and cities, including the potential impact of herd immunity on re-opening. Our current baselinemortality rate (IFR) is assumed to be 1.0% but we recognize there is substantial uncertainty about this number. Our model fits the death data equally well with alternative mortality rates of 0.5% or 1.2%, so this parameter is unidentified in our data. However, its value matters enormously for the extent to which various places can relax social distancing without spurring a resurgence of deaths.

Bayesian Estimation of Epidemiological Models

Bayesian Estimation of Epidemiological Models PDF Author: Jonas Arias
Publisher:
ISBN:
Category : COVID-19 (Disease)
Languages : en
Pages : 5

Book Description
We present a general framework for Bayesian estimation and causality assessment in epidemiological models. The key to our approach is the use of sequential Monte Carlo methods to evaluate the likelihood of a generic epidemiological model. Once we have the likelihood, we specify priors and rely on a Markov chain Monte Carlo to sample from the posterior distribution. We show how to use the posterior simulation outputs as inputs for exercises in causality assessment. We apply our approach to Belgian data for the COVID-19 epidemic during 2020. Our estimated time-varying-parameters SIRD model captures the data dynamics very well, including the three waves of infections. We use the estimated (true) number of new cases and the time-varying effective reproduction number from the epidemiological model as information for structural vector autoregressions and local projections. We document how additional government-mandated mobility curtailments would have reduced deaths at zero cost or a very small cost in terms of output.

COVID Transmission Modeling

COVID Transmission Modeling PDF Author: DM Basavarajaiah
Publisher: CRC Press
ISBN: 1000593215
Category : Mathematics
Languages : en
Pages : 458

Book Description
COVID Transmission Modeling: An Insight into Infectious Diseases Mechanism provides an interdisciplinary overview of the COVID-19 pandemic crisis and covers various aspects of newer modeling techniques and practical solutions for health emergencies. This book aims to formulate various innovative and pragmatic mathematical, statistical, and epidemiological models using COVID-19 real data sets. It emphasizes interdisciplinary theoretical postulates derived from practical insights and knowledge of public health. Each of the book’s 12 chapters provides invaluable and exploratory tools to enable explicit assumptions, highlights key health indicators, and determines the geometric progression and control measures of the disease. The present developed models will allow readers to extrapolate the exact reason for the outbreak and pave the way for scientific information on vaccine trials and socioeconomic, psychological, and disease burden worldwide. These advanced techniques of modeling and their applications are in greater need than ever for effective connection between mathematicians, statisticians, epidemiologists, researchers, clinicians, and policymakers for making appropriate decisions at the right time. With the advent of emerging health science, all models are demonstrated with real-life data sets and provided with illustrations and eye-catching graphs and diagrams so that the readers can easily understand the concept of COVID-19 pandemic interventions and their control measures, and their impact. Features Addresses all aspects of mitigation/control measures, estimation of transmission rate, economic impact assessment, genetic complexity of COVID-19, herd immunity, and various methods, including newer mathematical, statistical, and epidemiological models in the analysis of COVID-19 pandemic outbreak Covers the application of innovative, advanced statistical and epidemiological models and demonstrates possible solutions toward supportive treatment aspects of COVID-19 and its control measures Includes models that can easily be followed in formulating the mathematical derivations and key points Supplemented with ample illustrations, images, diagrams, and figures This book is aimed at postgraduate students studying medicine and healthcare, mathematics, and statistical information. Researchers will also find this book very helpful.

Computational Epidemiology

Computational Epidemiology PDF Author: Ellen Kuhl
Publisher: Springer Nature
ISBN: 3030828905
Category : Technology & Engineering
Languages : en
Pages : 312

Book Description
This innovative textbook brings together modern concepts in mathematical epidemiology, computational modeling, physics-based simulation, data science, and machine learning to understand one of the most significant problems of our current time, the outbreak dynamics and outbreak control of COVID-19. It teaches the relevant tools to model and simulate nonlinear dynamic systems in view of a global pandemic that is acutely relevant to human health. If you are a student, educator, basic scientist, or medical researcher in the natural or social sciences, or someone passionate about big data and human health: This book is for you! It serves as a textbook for undergraduates and graduate students, and a monograph for researchers and scientists. It can be used in the mathematical life sciences suitable for courses in applied mathematics, biomedical engineering, biostatistics, computer science, data science, epidemiology, health sciences, machine learning, mathematical biology, numerical methods, and probabilistic programming. This book is a personal reflection on the role of data-driven modeling during the COVID-19 pandemic, motivated by the curiosity to understand it.

SIR - Model Supported by a New Density

SIR - Model Supported by a New Density PDF Author: Marcus Hellwig
Publisher: Springer Nature
ISBN: 3031052730
Category : Mathematics
Languages : en
Pages : 73

Book Description
The SIR - model supported by a new density and its derivatives receive a statistical data background from frequency distributions, from whose parameter values over the new density distribution a quality-oriented probability of the respective infection process and its future can be concluded. Thus the COVID - management receives a functionally model basis for the preventive control of the components time planning, cost development, quality management and personnel and material employment.

Predictive Models for Decision Support in the COVID-19 Crisis

Predictive Models for Decision Support in the COVID-19 Crisis PDF Author: Joao Alexandre Lobo Marques
Publisher: Springer Nature
ISBN: 3030619133
Category : Technology & Engineering
Languages : en
Pages : 103

Book Description
COVID-19 has hit the world unprepared, as the deadliest pandemic of the century. Governments and authorities, as leaders and decision makers fighting the virus, enormously tap into the power of artificial intelligence and its predictive models for urgent decision support. This book showcases a collection of important predictive models that used during the pandemic, and discusses and compares their efficacy and limitations. Readers from both healthcare industries and academia can gain unique insights on how predictive models were designed and applied on epidemic data. Taking COVID19 as a case study and showcasing the lessons learnt, this book will enable readers to be better prepared in the event of virus epidemics or pandemics in the future.

COVID-19 Epidemiology and Virus Dynamics

COVID-19 Epidemiology and Virus Dynamics PDF Author: Till D. Frank
Publisher: Springer Nature
ISBN: 3030971783
Category : Science
Languages : en
Pages : 367

Book Description
This book addresses the COVID-19 pandemic from a quantitative perspective based on mathematical models and methods largely used in nonlinear physics. It aims to study COVID-19 epidemics in countries and SARS-CoV-2 infections in individuals from the nonlinear physics perspective and to model explicitly COVID-19 data observed in countries and virus load data observed in COVID-19 patients. The first part of this book provides a short technical introduction into amplitude spaces given by eigenvalues, eigenvectors, and amplitudes.In the second part of the book, mathematical models of epidemiology are introduced such as the SIR and SEIR models and applied to describe COVID-19 epidemics in various countries around the world. In the third part of the book, virus dynamics models are considered and applied to infections in COVID-19 patients. This book is written for researchers, modellers, and graduate students in physics and medicine, epidemiology and virology, biology, applied mathematics, and computer sciences. This book identifies the relevant mechanisms behind past COVID-19 outbreaks and in doing so can help efforts to stop future COVID-19 outbreaks and other epidemic outbreaks. Likewise, this book points out the physics underlying SARS-CoV-2 infections in patients and in doing so supports a physics perspective to address human immune reactions to SARS-CoV-2 infections and similar virus infections.

COVID Transmission Modelling

COVID Transmission Modelling PDF Author: D. M. Basavarajaiah
Publisher: CRC Press
ISBN: 9781032069708
Category : COVID-19 (Disease)
Languages : en
Pages : 408

Book Description
"This book will explore and formulate new mathematical/statistical and epidemiological modelling based on the research findings. It covers all the aspects of mitigation, estimation of transmission rate, control measures, economic impact assessment, genetic complexity of COVID and herd immunity"--

How to Go Viral: a COVID-19 Model with Endogenously Time-varying Parameters

How to Go Viral: a COVID-19 Model with Endogenously Time-varying Parameters PDF Author: Paul Ho
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description