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Author: Eugenio Muller Publisher: Elsevier ISBN: 0323142923 Category : Science Languages : en Pages : 730
Book Description
Brain Messengers and the Pituitary discusses the significant advances in neurotransmission and in understanding the physiology and pathophysiology of neuroendocrine control. This book is organized into seven chapters and begins with a discussion on the main biochemical and electrophysiological mechanisms underlying synaptic communication and the cotransmission and receptor plasticity. The following chapters describe the topographical localization and function of classical neurotransmitter and neuropeptide neurons. This book then presents the evidence on pituitary function control by the brain through specific hypophysiotropic regulatory hormones in relation to the secretion of adrenocorticotropic hormone and pro-opiomelanocortin-derived peptides, growth hormone, gonadotropins, prolactin, and thyroid-stimulating hormone. A chapter focuses on the neuroendocrine effects of an increasing number of neuropeptides. This text further deals with the role of pituitary gland as the target of central nervous system-derived and peripheral hormonal influences. The concluding chapters look into the experimental evidence linking brain neurotransmitters to the secretion of hypothalamic hormones and to anterior pituitary hormones or to neuroendocrine feedback regulation. These chapters also explore the evidence for neurotransmitter-neuropeptide dysfunction as an etiology for specific neuroendocrine disorders and the potential of the neuropharmacologic approach to the diagnosis and therapy. Clinical neuroendocrinologists and researchers and students in neuroendocrinology, neurobiology, neuropharmacology, neurophysiology, and psychiatry will find this book invaluable.
Author: Eugenio Muller Publisher: Elsevier ISBN: 0323142923 Category : Science Languages : en Pages : 730
Book Description
Brain Messengers and the Pituitary discusses the significant advances in neurotransmission and in understanding the physiology and pathophysiology of neuroendocrine control. This book is organized into seven chapters and begins with a discussion on the main biochemical and electrophysiological mechanisms underlying synaptic communication and the cotransmission and receptor plasticity. The following chapters describe the topographical localization and function of classical neurotransmitter and neuropeptide neurons. This book then presents the evidence on pituitary function control by the brain through specific hypophysiotropic regulatory hormones in relation to the secretion of adrenocorticotropic hormone and pro-opiomelanocortin-derived peptides, growth hormone, gonadotropins, prolactin, and thyroid-stimulating hormone. A chapter focuses on the neuroendocrine effects of an increasing number of neuropeptides. This text further deals with the role of pituitary gland as the target of central nervous system-derived and peripheral hormonal influences. The concluding chapters look into the experimental evidence linking brain neurotransmitters to the secretion of hypothalamic hormones and to anterior pituitary hormones or to neuroendocrine feedback regulation. These chapters also explore the evidence for neurotransmitter-neuropeptide dysfunction as an etiology for specific neuroendocrine disorders and the potential of the neuropharmacologic approach to the diagnosis and therapy. Clinical neuroendocrinologists and researchers and students in neuroendocrinology, neurobiology, neuropharmacology, neurophysiology, and psychiatry will find this book invaluable.
Author: Richard E. Brown Publisher: Cambridge University Press ISBN: 9780521426657 Category : Medical Languages : en Pages : 434
Book Description
This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Author: National Academy of Sciences Publisher: National Academies Press ISBN: 0309045290 Category : Medical Languages : en Pages : 195
Book Description
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Author: National Research Council Publisher: National Academies Press ISBN: 0309069882 Category : Social Science Languages : en Pages : 610
Book Description
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Author: Constantine A. Stratakis Publisher: Academic Press ISBN: 0128145382 Category : Science Languages : en Pages : 312
Book Description
Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. - Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism - Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics - Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Author: Stephen H. Koslow Publisher: Cambridge University Press ISBN: 1107033233 Category : Medical Languages : en Pages : 409
Book Description
A concise review of current research into suicide providing a guide to understanding this disease and its increasing incidence globally.
Author: Robert Vink Publisher: University of Adelaide Press ISBN: 0987073052 Category : Medical Languages : en Pages : 354
Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author: National Research Council Publisher: National Academies Press ISBN: 0309045312 Category : Science Languages : en Pages : 167
Book Description
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Author: Antonino Belfiore Publisher: Springer ISBN: 9783319446745 Category : Medical Languages : en Pages : 0
Book Description
This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Author: Michael Wilkinson Publisher: Cambridge University Press ISBN: 1316645193 Category : Medical Languages : en Pages : 207
Book Description
A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Author: Eugenio Muller
Author: Eugenio Muller
Author: Richard E. Brown
Author: National Academy of Sciences
Author: National Research Council
Author: Constantine A. Stratakis
Author: Stephen H. Koslow
Author: Robert Vink
Author: National Research Council
Author: Antonino Belfiore
Author: Michael Wilkinson