Brain Biochemistry and Brain Disorders PDF Download

Author: Philip Gordon Strange
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 368

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Book Description
This textbook gives students of neuroscience, psychology, and related subjects a thorough introduction to this important topic and a foundation for future study. Key concepts are explained clearly and, by bridging the gap between basic and clinical sciences, the book provides a new perspective on brain function and brain disorders. Its unique approach means that it will give researchers new insights into their subject, as well as acting as a concise review and reference text.

Author: Sudhir Kumar
Publisher: Elsevier
ISBN: 1483153592
Category : Medical
Languages : en
Pages : 634

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Book Description
Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids. This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents. This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.

Author: H. S. Bachelard
Publisher: Springer
ISBN: 1489933921
Category : Medical
Languages : en
Pages : 72

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Book Description
The brain is the most complex and highly of semi-permeable excitable membranes which specialised of all mammalian organs. Under can be caused, rapidly and transiently, to under standing the complexity of its function remains go changes in permeability to small chemical man's greatest challenge. The functional unit is molecules and to cations. The highly specialised the neurone, or excitable nerve cell, making ana nature of the constituent cells, with their unique tomical and chemical connections with other function and specificity, is c10sely related to units in the system. Many of the essential bio the structure of the whole tissue. The underlying chemical connections of the nerve cell are de chemical processes cannot be discussed or seen pendent upon special morphological features: in perspective without constant awareness of synaptic contact is mediated by chemical mol related aspects of physiology and morphology. ecules, 'neuro-transmitters' which ensure the The hrain is structurally extraordinarily com continued propagation of electrical impulses plex in its distinct anatomical regions, each of through sequential units of the system. Also which is heterogeneous in the types and struc c10sely related to the morphology of the ner tures of the constituent cells. vous system is the chemical energy expended in One aspect of the biochemical function of maintaining distribution gradients of cations the brain can be seen in its efficient production across cellular membranes. Chemical neuro of the energy required to support the unique pro transmission results in an alteration in cation cesses referred to above.

Author: National Academy of Sciences
Publisher: National Academies Press
ISBN: 0309045290
Category : Medical
Languages : en
Pages : 195

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Book Description
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Author: William Walsh
Publisher: Skyhorse Publishing, Inc.
ISBN: 1626361282
Category : Health & Fitness
Languages : en
Pages : 225

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Book Description
A veteran research scientist who has spent decades establishing biochemical treatment protocols for patients with ADHD, Alzheimer's disease and various mental disorders challenges popular opinions about psychiatric drugs to make recommendations for drug-free nutrient therapies that normalize the brain without producing serious side effects. 15,000 first printing.

Author: Herman S. Bachelard
Publisher: Springer Science & Business Media
ISBN: 9400959419
Category : Science
Languages : en
Pages : 79

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Book Description
The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the frontiers of his discipline. New research work is published in a perplexing diversity of publications and is inevitably concerned with the minutiae of the subject. The sheer number of research journals and papers also causes confusion and difficulties of assimilation. Review articles usually presuppose a back ground knowledge of the field and are inevitably rather restricted in scope. There is thus a need for short but authoritative introductions to those areas of modern biological research which are either not dealt with in standard introductory textbooks or are not dealt with in suffi cient detail to enable the student to go on from them to read scholarly reviews with profit. This series of books is designed to satisfy this need. The authors have been asked to produce a brief outline of their subject assuming that their readers will have read and remembered much of a standard introductory textbook on biology. This outline then sets out to provide by building on this basis, the conceptual framework within which modern research work is progressing and aims to give the reader an indication of the problems, both conceptual and practical, which must be overcome if progress is to be maintained.

Author: A.N. Davison
Publisher: Elsevier
ISBN: 0323154255
Category : Science
Languages : en
Pages : 360

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Book Description
Biochemical Correlates of Brain Structure and Function deals with the biochemical correlates of brain structure and function, providing some examples of contemporary work interrelating structure with function of the nervous system. The developing brain provides a system for this kind of study, but broad correlates are also drawn between changing biochemistry and increasing physiological activity. This book is organized into nine chapters and begins with an overview of biochemical, morphological, and functional changes in the developing brain, as well as the underlying molecular basis of nerve differentiation and growth of the developing brain. An account of the concept of the cell cycle and its control is also given. The reader is methodically introduced to the properties of the developing retina and its functional biochemistry, with specific reference to the cyclic nucleotides; the use of selective lesioning to delineate GABA-ergic and cholinergic tracts as well as the catecholamine pathways; and cerebral blood flow alteration in concert with mental activity. The remaining chapters explore regions of the brain with altered glucose utilization in response to changes in local functional activity; the physiologically important factors regulating the supply of oxygen and glucose and the relation of metabolic rate to the metabolic state of the brain; and varying aspects of behavioral neurochemistry. This book is intended for chemists and biologists as well as students of biochemistry.

Author: Robert E. Bowman
Publisher: Springer Science & Business Media
ISBN: 1468490486
Category : Psychology
Languages : en
Pages : 376

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Book Description
ment of mental retardation as in the young human. These two facts together suggest that the disrup tion of brain protein synthesis by high phenylala mine levels in infants may account for the mental retardation observed later in these children. Much work remains to be done to confi~m this possibility. However, it is clear from the review and research described by Waisman that neurochemis try has the tools that will lead to an understand ing of - and therefore perhaps control of - these inborn errors of metabolism which otherwise can lead to lifetimes of personal tragedy for the af fected persons and their families. The final section of these Proceedings deals with neurochemical processes which occur during brief behavioral experiences, particularly learn ing. The reported research has been motivated by the search for processes which underlie the encoding of memory, although the identification of these processes is not yet certain in the various studies. Geller and Jarvik begin with a discussion of short term and long term memory storage processes, and describe the induction of retrograde amnesia by various agents as evidence for these processes.

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309069882
Category : Social Science
Languages : en
Pages : 610

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Book Description
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Author: Harun K M Yusuf
Publisher: World Scientific Publishing Company
ISBN: 9813103779
Category : Science
Languages : en
Pages : 407

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Book Description
The understanding of brain functions at the molecular level has been one of the greatest challenges for man. Up to now, the basis of its most important functions, including the development of consciousness and personality, and the mechanism of learning and memory, remains unknown. However, the pace of discovery at the morphological, cellular, neurophysiological and molecular levels of brain functions has been quite rapid in the past decades. Neuroscience has therefore been an over-advancing and extremely fascinating field of research which has made a significant contribution to our understanding of brain structure, chemistry and function. This book gives a concise synopsis of our present day knowledge of the basic chemical principles of how the brain works and how the brain develops. It is quite an intelligible approach to ordering the tremendous amount of knowledge accumulated so far in various research fields, particularly neurochemistry. Special emphasis has been given to the chemical language of many aspects of brain development as related to morphology and function. The final part is devoted to the plasticity of the brain and the impact of malnutrition and environment in early life on the development of mental functions. Particularly valuable are the many references to original literature, especially when controversial issues are discussed.The book is well written in an easily understandable manner and would be of great help to all students and scientists interested in the extensive and demanding field of neuroscience.