Brain Activity in People with Spinal Cord Injury, with Applications to Brain-computer Interfaces for Neuroprosthetic Control PDF Download

Author: Peter R. Boord
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 0

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Author: Gernot Müller-Putz
Publisher: Springer Nature
ISBN: 3030685454
Category : Medical
Languages : en
Pages : 377

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Book Description
This book provides a comprehensive overview of the current state of the art of practical applications of neuroprosthesis based on functional electrical stimulation for restoration of motor functions lost by spinal cord injury and discusses the use of brain-computer interfaces for their control. The book covers numerous topics starting with basics about spinal cord injury, electrical stimulation, electrical brain signals and brain-computer interfaces. It continues with an overview of neuroprosthetic solutions for different purposes and non-invasive and invasive brain-computer interface implementations and presents clinical use cases and practical applications of BCIs. Finally, the authors give an outlook on cutting edge research with a high potential for clinical translation in the near future. All authors committed themselves to use easy-to-understand language and to avoid very specific information, focusing instead on the essential aspects. This makes this book an ideal choice not only for researchers and clinicians at all stages of their education interested in the topic of brain-computer interface-controlled neuroprostheses, but also for end users and their caregivers who want to inform themselves about the current technological possibilities to improve paralyzed motor functions.

Author: Cesar Marquez-Chin
Publisher: Springer Nature
ISBN: 3031016084
Category : Science
Languages : en
Pages : 133

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Book Description
Stroke and spinal cord injury often result in paralysis with serious negative consequences to the independence and quality of life of those who sustain them. For these individuals, rehabilitation provides the means to regain lost function. Rehabilitation following neurological injuries has undergone revolutionary changes, enriched by neuroplasticity. Neuroplastic-based interventions enhance the efficacy and continue to guide the development of new rehabilitation strategies. This book presents three important technology-based rehabilitation interventions that follow the concepts of neuroplasticity. The book also discusses clinical results related to their efficacy. These interventions are: functional electrical stimulation therapy, which produces coordinated muscle contractions allowing people with paralysis to perform functional movements with rich sensory feedback; robot-assisted therapy, which uses robots to assist, resist, and guide movements with increased intensity while also reducing the physical burden on therapists; and brain–computer interfaces, which make it possible to verify the presence of motor-related brain activity during rehabilitation. Further, the book presents the combined use of these three technologies to illustrate some of the emerging approaches to the neurorehabilitation of voluntary movement. The authors share their practical experiences obtained during the development and clinical testing of functional electrical stimulation therapy controlled by a brain–computer interface as an intervention to restore reaching and grasping.

Author: Jonathan Wolpaw
Publisher: Oxford University Press
ISBN: 0199921482
Category : Medical
Languages : en
Pages : 419

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Book Description
A recognizable surge in the field of Brain Computer Interface (BCI) research and development has emerged in the past two decades. This book is intended to provide an introduction to and summary of essentially all major aspects of BCI research and development. Its goal is to be a comprehensive, balanced, and coordinated presentation of the field's key principles, current practice, and future prospects.

Author:
Publisher: Elsevier
ISBN: 0444639330
Category : Medical
Languages : en
Pages : 392

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Book Description
Brain-Computer Interfacing, Volume 168, not only gives readers a clear understanding of what BCI science is currently offering, but also describes future expectations for restoring lost brain function in patients. In-depth technological chapters are aimed at those interested in BCI technologies and the nature of brain signals, while more comprehensive summaries are provided in the more applied chapters. Readers will be able to grasp BCI concepts, understand what needs the technologies can meet, and provide an informed opinion on BCI science. - Explores how many different causes of disability have similar functional consequences (loss of mobility, communication etc.) - Addresses how BCI can be of use - Presents a multidisciplinary review of BCI technologies and the opportunities they provide for people in need of a new kind of prosthetic - Offers a comprehensive, multidisciplinary review of BCI for researchers in neuroscience and traumatic brain injury that is also ideal for clinicians in neurology and neurosurgery

Author: Jens Schouenborg
Publisher: Elsevier
ISBN: 0444538151
Category : Medical
Languages : en
Pages : 297

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Few examples of the contribution of animal research for clinical application of Deep Brain Stimulation, Christelle Baunez 13. Deep Brain Stimulation- challenges and opportunities, Andres M. Lozano 14. Cochlear and retinal prostheses: an overview of safety and efficacy, neural rescue and brain plasticity studies, Rob Shepherd 15. Cochlear implants: Matching the prosthesis to the brain and facilitating desired plastic changes in brain function, Blake Wilson 16. Neural microstimulation parameters and interfacial quality effects, Kevin Otto 17. The Feasibility of a Cortically Based Visual Prosthesis: Stimulation and Recording in Monkey Visual Cortex with Chronically Implanted Microelectrode Arrays, Dick Normann 18. Physical and chemical factors influencing the biocompatibility of an implant, Lars Magnus Bjursten 19. A Biologically-based Design Strategy for Reducing the Foreign Body Response to Chronically Implanted Neural Interfaces, Patrick Tresco 20. Biocompatibility and CNS: need for standardization? Cecilia Eriksson Linsmeier 21. Reviving the CPG after spinal cord injury, Serge Rossignol 22. What does the brain control? Gerald E. Loeb 23. Advanced use of electrical stimulation for recovery of function, Dejan B. Popovic 24. Restoring Standing and Walking by the Reactivation of Central Neural Networks, Vivian Mushahwar 25. Reanimating the arm and hand with intraspinal stimulation, Andrew Jackson 26. Ethics of Control and Consent in Brain Stimulation for Parkinson Disease, Paul J. Ford 27. Neuroprosthetics and Neuromarkers, Apostolos P. Georgopoulos 28. Neural Signal Processing: At the Interface Between Basic and Clinical Neuroscience, Partha P. Mitra 29. Inference of hand movements from population activity in monkey and human sensorimotor cortex: Towards Brain-Machine Interfaces, Ad Aertsen 30. Semiconductor Chips with Ion Channels, Nerve Cells and Brain Tissue, Peter Fromherz 31. Interfacing Neurons with Carbon Nanotubes: (re)engineering single-neuron excitability and network connectivity in Cultured Brain Circuits 32. Nanomodified surfaces and neurite outgrowth, Martin Kanje 33. Nanochannels for cell biology and DNA analysis, Jonas Tegenfeldt 34. Establishing Reliable Communication Across the Glial Scar: In-Situ Polymerization of Conjugated Polymers in Living Cortex, David C. Martin.

Author: Jonathan Carl Landes
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 203

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Book Description
Paralysis, due to spinal cord injury, amyotrophic lateral sclerosis (ALS), or stroke, is the result of severed communication between the brain and the motor periphery. Brain computer interfaces (BCIs) are neuroprosthetic devices that create novel communication pathways by measuring and transforming neural activity into operational commands. State of the art BCI systems measure brain activity using penetrating electrode arrays able to record from hundreds of individual cortical neurons simultaneously. Unfortunately, these systems are highly susceptible to signal degradation which limits their efficacy to 1-2 years. However, electrocorticography (ECoG) signals recorded from the surface of the brain deliver a more competitive balance between surgical risk, long-term stability, signal bandwidth, and signal-to-noise ratio when compared to both the aforementioned intracortical systems and the more common non-invasive electroencephalography (EEG) technologies.Historically, neural signals for controlling a computer cursor or robotic arm have been mapped to extrinsic, kinematic (i.e. position or velocity) variables. Although this strategy is adequate for use in simple environments, it may not be ideal for control of real-world prosthetic devices that are subject to external and unexpected forces. When reaching for an object, the trajectory of the hand through space can be defined in either extrinsic (e.g. Cartesian) or intrinsic (e.g. joint angles, muscle forces) frames of reference. During this movement, the brain has to perform a series of sensorimotor transformations that involve solving a complex, 2nd order differential equation (i.e. musculoskeletal biomechanics) in order to determine the appropriate muscle activations. Functional neuromuscular stimulation (FNS) is a desirable BCI application because it attempts to restore motor function to paralyzed limbs through electrical excitation of muscles. Rather than applying the conventional extrinsic kinematic control signals to such a system, it may be more appropriate to map neural activity to muscle activation directly and allow the brain to develop its own transfer function.This dissertation examines the application of intrinsic decoding schemes to control an upper limb using ECoG in non-human primates. ECoG electrode arrays were chronically implanted in rhesus monkeys over sensorimotor cortex. A novel multi-joint reaching task was developed to train the subjects to control a virtual arm simulating muscle and inertial forces. Utilizing a co-adaptive algorithm (where both the brain adapts via biofeedback and the decoding algorithm adapts to improve performance), new decoding models were initially built over the course of the first 3-5 minutes of each daily experimental session and then continually adapted throughout the day. Three subjects performed the task using neural control signals mapped to 1) joint angular velocity, 2) joint torque, and 3) muscle forces of the virtual arm. Performance exceeded 97%, 93%, and 89% accuracy for the three control paradigms respectively. Neural control features in the upper gamma frequency bands (70-115 and 130-175 Hz) were found to be directionally tuned in an ordered fashion, with preferred directions varying topographically in the mediolateral direction without distinction between motor and sensory areas. Long-term stability was demonstrated by all three monkeys, which maintained performance at 42, 55, and 57 months post-implantation. These results provide insights into the capabilities of sensorimotor cortex for control of non-linear multi-joint reaching dynamics and present a first step toward design of intrinsic, force-based BCI systems suitable for long-term FNS applications.

Author: Enrique Hortal
Publisher: Springer
ISBN: 3319957058
Category : Technology & Engineering
Languages : en
Pages : 118

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Book Description
This book reports on the development of different control tools for Brain-machine interface-based assistance and rehabilitation. Brain activity is analyzed with the purpose of classify mental tasks and detecting movement intentions in patients with impaired motility. Event-Related Desynchronization (ERD) and Event-Related Synchronization (ERS) are detected. Throughout this book, different control systems are presented and validated. This thesis, examined at the Miguel Hernández University of Elche, Spain, in 2016, received the award for best thesis in bioengineering from the Bioengineering group of the Spanish Committee of Automatic Control (CEA) in 2017.

Author: Christoph Guger
Publisher: Springer Nature
ISBN: 3031494571
Category : Technology & Engineering
Languages : en
Pages : 149

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Book Description
This book showcases recent trends in brain-computer interface development. It highlights fascinating results in areas such as language decoding, spinal cord stimulation to enable gait and to restore hand functions. The contributions are based on the 12 nominated brain-computer interface projects of the BCI Award 2022. Every year an international jury selects the most innovate BCI projects and nominates 12 projects before selecting the 1st, 2nd and 3rd place winners. In the book, each project is described in detail by the team of scientists behind it, and the editors provide a concluding discussion of the highlights and overall progress in the field.

Author: Jonathan Wolpaw
Publisher: OUP USA
ISBN: 0195388852
Category : Computers
Languages : en
Pages : 420

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Book Description
In the last 15 years, a recognizable surge in the field of Brain Computer Interface (BCI) research and development has emerged. This emergence has sprung from a variety of factors. For one, inexpensive computer hardware and software is now available and can support the complex high-speed analyses of brain activity that is essential is BCI. Another factor is the greater understanding of the central nervous system including the abundance of new information on the nature and functional correlates of brain signals and improved methods for recording these signals in both the short-term and long-term. And the third, and perhaps most significant factor, is the new recognition of the needs and abilities of people disabled by disorders such as cerebral palsy, spinal cord injury, stroke, amyotrophic lateral sclerosis (ALS), multiple sclerosis, and muscular dystrophies. The severely disabled are now able to live for many years and even those with severely limited voluntary muscle control can now be given the most basic means of communication and control because of the recent advances in the technology, research, and applications of BCI. This book is intended to provide an introduction to and summary of essentially all major aspects of BCI research and development. Its goal is to be a comprehensive, balanced, and coordinated presentation of the field's key principles, current practice, and future prospects.