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Author: Tiantian Xu Publisher: ISBN: 9781267542731 Category : Blood flow Languages : en Pages : 150
Book Description
Cardiovascular disease is the leading cause death in the United States. Although emergency surgery and medicine can be used for cardiovascular disease treatment, the survivors will suffer for it afterwards. Ultrasound blood flow measurement provides a noninvasive way for cardiovascular diseases diagnosis. In this dissertation, three algorithms for blood flow velocity measurements were investigated and optimized. Feature tracking has been previously proposed for vector velocity measurement. In Chapter 3, the optimal amplitude and time thresholds for feature extraction were investigated to minimize flow estimate variance while providing sufficient spatial and temporal coverage of flow area. A new method of lateral blood flow velocity measurement was investigated in Chapter 4 using the observation that the speckle pattern corresponding to blood reflectors stretches if the blood is moving in the same direction as the electronically-controlled transducer line selection in a 2-D image. The results demonstrated that there is a linear relationship between the speckle size and blood flow velocity, which can be used for ultrasound blood flow velocity measurement. To improve the lateral blood flow estimation performance using speckle size estimation, the relationship between blood flow velocity estimation for flow purely lateral to the ultrasound beam and flow gradient, random scatterer movement and ROI size was investigated and quantitatively assessed in Chapter 5. By changing the ROI sizes, the results showed that different optimal ROI sizes exist in different flow profile regarding the flow gradient and random scatterer movement. The method of blood flow velocity estimation using speckle size estimation was further tested in vivo with jugular vein blood flow from human subjects in Chapter 6. The results showed that speckle size estimation has a comparable estimation performance to spectral Doppler with potential time savings. Finally, a two-dimensional blood flow velocity estimation algorithm using apparent speckle pattern angle was proposed in Chapter 7. The apparent angle of speckle pattern changes with different scan velocities due to mis-registration between the ultrasound beam and scatterers. Results showed that this algorithm can resolve the amplitude and angle of the blood flow simultaneously.
Author: Josef F. Bille Publisher: Springer ISBN: 3030166384 Category : Medical Languages : en Pages : 407
Book Description
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Author: Jørgen Arendt Jensen
Author: Jørgen Arendt Jensen
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Author: 
Author: Peter Munk
Author: Katherine Whittaker Ferrara
Author: Tiantian Xu
Author: Mario Basic
Author: Elena Štúriková
Author: Hideyuki Hasegawa
Author: Josef F. Bille