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Author: Gerhard F. Fueger Publisher: Springer Science & Business Media ISBN: 9400960301 Category : Medical Languages : en Pages : 498
Book Description
G. F. FUEGER Among the many processes in Physiology few appear mo~e inviting to be studied by tracers and external imaging than the variety of the routes of migratory (blood) cells in health and disease. Much emphasis has been placed lately on the methods of labelling of the white blood cells. It is obviously quite important and necessary to refine the methods of leucocytic labelling, particularly to search for ways to label selectively a specific group of white blood cells, but there is also the need to review and keep abreast with the developing knowledge of the white blood cells themselves, especially their behaviour under pathological conditions, as seen by histology and scintigraphy, their biological properties, their immunological characteristics and the mechanisms of the control of leucocytic functions. Similarly, it appears desirable to analyze animal models of inflammation as well as to review the dosimetry and the biodistribution of labelled white blood cells in humans. This book is the result of a cooperative effort to review certain highlights of the physiology of leucocytes, labelled and unlabelled, as a corollary to the effort concerning the labelling of white blood cells. In preparing this book we aim for a better understanding and definition of the goals to be achieved by the successful labelling of the migratory cells of the body. XI CONTRIBUTORS Becker, H. Medizinische Universitaetsklinik der Uni versitaet Graz, Graz, Landeskrankenhaus, haus, Austria Bjurman, B. Department of Radiation Physics, General Hospital, Malmoe, Sweden Chiles, C.
Author: Gerhard F. Fueger Publisher: Springer Science & Business Media ISBN: 9400960301 Category : Medical Languages : en Pages : 498
Book Description
G. F. FUEGER Among the many processes in Physiology few appear mo~e inviting to be studied by tracers and external imaging than the variety of the routes of migratory (blood) cells in health and disease. Much emphasis has been placed lately on the methods of labelling of the white blood cells. It is obviously quite important and necessary to refine the methods of leucocytic labelling, particularly to search for ways to label selectively a specific group of white blood cells, but there is also the need to review and keep abreast with the developing knowledge of the white blood cells themselves, especially their behaviour under pathological conditions, as seen by histology and scintigraphy, their biological properties, their immunological characteristics and the mechanisms of the control of leucocytic functions. Similarly, it appears desirable to analyze animal models of inflammation as well as to review the dosimetry and the biodistribution of labelled white blood cells in humans. This book is the result of a cooperative effort to review certain highlights of the physiology of leucocytes, labelled and unlabelled, as a corollary to the effort concerning the labelling of white blood cells. In preparing this book we aim for a better understanding and definition of the goals to be achieved by the successful labelling of the migratory cells of the body. XI CONTRIBUTORS Becker, H. Medizinische Universitaetsklinik der Uni versitaet Graz, Graz, Landeskrankenhaus, haus, Austria Bjurman, B. Department of Radiation Physics, General Hospital, Malmoe, Sweden Chiles, C.
Author: National Research Council Publisher: National Academies Press ISBN: 0309134153 Category : Medical Languages : en Pages : 173
Book Description
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Author: Tod W. Speer Publisher: Lippincott Williams & Wilkins ISBN: 1451153260 Category : Medical Languages : en Pages : 564
Book Description
Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.
Author: E. Gordon DePuey Publisher: Lippincott Williams & Wilkins ISBN: 9780781720076 Category : Medical Languages : en Pages : 366
Book Description
Cardiac SPECT Imaging, Second Edition offers the best of all possible worlds--a critical topic, internationally recognized authors and cutting-edge coverage. It guides you through all aspects of the modality--from basic principles (acquiring and processing images, quality control)...and clinical applications (evaluating myocardial infarction and coronary artery disease)...to the very latest equipment. It even compares SPECT with other modalities (PET, CT, MRI, and echocardiography) to ensure smart, cost-effective decisions by both the cardiologist and nuclear medicine physician.Look for new chapters on attenuation correction, gated perfusion SPECT, radiopharmaceuticals, and myocardial perfusion SPECT, as well as the very latest on myocardial perfusion SPECT in conjunction with exercise and pharmacologic stress, assessment of perfusion/viability with Tc-99m agents, how SPECT compares with other advanced cardiac imaging modalities, and more!
Author: Ilse Zolle Publisher: Springer Science & Business Media ISBN: 3540339906 Category : Medical Languages : en Pages : 354
Book Description
Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.
Author: J.C Baron Publisher: Springer Science & Business Media ISBN: 9401135282 Category : Medical Languages : en Pages : 206
Book Description
Imaging of the Dopaminergic system in the human brain with the in vivo use of Positron Emis sion Tomography has emerged in the late 1980s as a tool of major importance in Clinical Neuros ciences and Pharmacology. The last few years have witnessed the rapid development of new radiotracers specific to receptors, reuptake sites and enzymes of the dopamine system; the application of these radiotracers has led to major breakthroughs in the pathophysiology and therapy of movement disorders and schizophrenic-like psychoses. This book is the first to collect, in a single volume, state-of-the-art contributions to the various aspects of this research. Its contents address methodological issues related to the design, labelling, quantitative imaging and compartmental modelisation of radioligands of the post-synaptic, pre-synaptic and enzyme sites of the dopamine system and to their use in clinical research in the fields of Parkinson's disease as well as other movement disorders, psychoses and neuroleptic receptor occupancy. The chapters were written by leading European scientists in the field of Positron Emission Tomography, gathered together in Caen (France, November 1990) under the aegis of the EEC Concerted Action on "PET Investigations of Cellular Regeneration and Degeneration. This book provides a current and comprehensive overview on PET studies of the brain dopamine system which should aid and interest neurologists, psychiatrists, pharmacologists and medical imaging scientists. J.C. Baron D. Comar L. Farde J.L. Martinot B. Mazoyer August 1991 ix LIST OF CONTRffiUTORS Dr Yves Agid DrL.
Author: B.M. Mazoyer Publisher: Springer Science & Business Media ISBN: 9401116202 Category : Medical Languages : en Pages : 270
Book Description
Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations? These questions have been addressed for a long time and no satisfactory answer has yet been given. This book, which derives from an EEC workshop organized in the frame of the Concerted Action on `PET Investigation of Cellular Regeneration and Degeneration', held in Lyon in February 1992, gives the present state of knowledge in this field based on the most recent studies. Contributions from 24 leading European and American scientists are presented and discussed in the following four parts: biochemistry and animal studies; amino acids labelling with positron emittors, quality control and metabolites measurement; kinetic modelling of amino acids transport, metabolism, and protein incorporation; clinical use of amino acids. This book will aid and interest biochemists, radiochemists, pharmacologists, neurologists, oncologists and medical imaging scientists.
Author: Bital Savir-Baruch Publisher: Springer ISBN: 3319246364 Category : Medical Languages : en Pages : 253
Book Description
This book is a learning aid and reference tool that provides all the important information pertaining to radioactive tracers within a single, easy-to-read volume. It introduces a new learning methodology that will help the reader to recall key facts on each tracer, including production, physical and chemical characteristics, study protocols, mechanism of action, distribution, and clearance. In addition, normal and abnormal tracer distributions are graphically reproduced on an outline of the human body using multiple colors. The book will be of value for all radiologists and medical students seeking a reliable source of essential information on radioactive tracers that can be readily consulted during everyday practice and used in preparation for examinations.
Author: Gerhard F. Fueger
Author: Gerhard F. Fueger
Author: National Research Council
Author: Tod W. Speer
Author: National Library of Medicine (U.S.)
Author: National Library of Medicine (U.S.)
Author: E. Gordon DePuey
Author: Ilse Zolle
Author: J.C Baron
Author: B.M. Mazoyer
Author: Bital Savir-Baruch