Bioprocess Intensification PDF Download

Author: Dirk Holtmann
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110760371
Category : Science
Languages : en
Pages : 553

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Book Description
Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.

Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
ISBN: 3527347690
Category : Technology & Engineering
Languages : en
Pages : 404

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Book Description
Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.

Author: Andrzej Górak
Publisher: Royal Society of Chemistry
ISBN: 178801457X
Category : Technology & Engineering
Languages : en
Pages : 456

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Book Description
In recent years bioprocessing has increased in popularity and importance, however, bioprocessing still poses various important techno-economic and environmental challenges, such as product yields, excessive energy consumption for separations in highly watery systems, batch operation or the downstream processing bottlenecks in the production of biopharmaceutical products. Many of those challenges can be addressed by application of different process intensification technologies discussed in the present book. The first book dedicated entirely to this area, Intensification of Biobased Processes provides a comprehensive overview of modern process intensification technologies used in bioprocessing. The book focusses on four different categories of biobased products: bio-fuels and platform chemicals; cosmeceuticals; food products; and polymers and advanced materials. It will cover various intensification aspects of the processes concerned, including (bio)reactor intensification; intensification of separation, recovery and formulation operations; and process integration. This is an invaluable source of information for researchers and industrialists working in chemical engineering, biotechnology and process engineering.

Author: Fernando Israel Gómez-Castro
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110592797
Category : Technology & Engineering
Languages : en
Pages : 389

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Book Description
Intensified processes have found widespread application in the chemical and petrochemical industries. The use of intensified systems allows for a reduction of operating costs and supports the "greening" of chemical processes. However, the design of intensified equipment requires special methodologies. This book describes the fundamentals and applications of these design methods, making it a valuable resource for use in both industry and academia.

Author: Juan Gabriel Segovia-Hernandez
Publisher: Elsevier
ISBN: 0323886329
Category : Technology & Engineering
Languages : en
Pages : 252

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Book Description
Improvements in Bio-Based Building Blocks Production Through Process Intensification and Sustainability Concepts discusses new information on the production and cost of bio-based building blocks. From a technical point-of-view, almost all industrial materials made from fossil resources can be substituted using bio-based counterparts. However, the cost of bio-based production in many cases exceeds the cost of petrochemical production. In addition, new products must be proven to perform at least as good as their petrochemical equivalents, have a lower environmental impact, meet consumer demand for environmentally-friendly products, factor in population growth, and account for limited supplies of non-renewables. This book outlines the application of process intensification techniques which allow for the generation of clean, efficient and economical processes for bio-based chemical blocks production. Includes synthesis and process design strategies for intensified processes Describes multi-objective optimization applied to the production of bio-based building blocks Presents the controllability of processes where the production of bio-based building blocks is involved Provides examples using aspen and MATLAB Introduces several sustainable indexes to evaluate production processes Presents process intensification techniques to improve performance in productive processes

Author: Juan Gabriel Segovia-Hernández
Publisher: Springer
ISBN: 3319283928
Category : Science
Languages : en
Pages : 341

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Book Description
This book will provide researchers and graduate students with an overview of the recent developments and applications of process intensification in chemical engineering. It will also allow the readers to apply the available intensification techniques to their processes and specific problems. The content of this book can be readily adopted as part of special courses on process control, design, optimization and modelling aimed at senior undergraduate and graduate students. This book will be a useful resource for researchers in process system engineering as well as for practitioners interested in applying process intensification approaches to real-life problems in chemical engineering and related areas.

Author: Ravindra Pogaku
Publisher: Springer Science & Business Media
ISBN: 1461462088
Category : Science
Languages : en
Pages : 405

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Book Description
Environmental sustainability and development is of critical importance. Technological advances in the production of new energy sources are making their way into our lives in more and more depth every day. However, there is an urgent need to address the technological challenges and advancement of the various chemical and bio-processes to maintain the dynamic sustainability of our energy needs. Toward that end, an attempt is being made to look at recent advances, key issues still faced and where possible, offer suggestions on alternative technologies to optimize sustainable processes. Still considered a new area of science, energy sources themselves are still being 'discovered'...meaning, what is financially viable in the current marketplace is changing. For example, energy from plants has not been financially viable in the past because of the high cost of growing, harvesting, breaking down cell walls, disposal of waste products, etc. Materials used to derive energy from sustainable resources is changing, making previously high-cost processes more efficient. It is crucial that the industry as a while works in tandem to develop crops that new technological advances make financially feasible. This book will cover recent advances in the chemicals, bioprocesses and other materials used in growing and extracting energy from sustainable products. Membrane/cell wall digestion issues will also be covered as well as recovering mamixal amounts of energy from sources to limit waste. Finally a section on safety and control will be presented with has been poorly covered in other publications. ​

Author: Sudhir P. Singh
Publisher: John Wiley & Sons
ISBN: 1119717264
Category : Science
Languages : en
Pages : 452

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Book Description
Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance. The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader’s knowledge of the applications of different microbial diversity and reveal new avenues of research investigation. Readers will also benefit from: A thorough introduction to microbial biodiversity and bioprospecting An exploration of anti-ageing and skin lightening microbial products and microbial production of anti-cancerous biomolecules A treatment of UV protective compounds from algal biodiversity and polysaccharides from marine microalgal sources Discussions of microbial sources of insect toxic proteins and the role of microbes in bio-surfactants production Perfect for academics, scientists, researchers, graduate and post-graduate students working and studying in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology, Bioprospecting of Microorganism-Based Industrial Molecules is an indispensable guide for anyone looking for a comprehensive overview of the subject.

Author: Clemens Posten
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 311077335X
Category : Science
Languages : en
Pages : 392

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Book Description
Bioprocess engineering employs microorganisms to produce biological products for medical and industrial applications. The book covers engineering tasks around- the cultivation process in bioreactors including media design, feeding strategies, or cell harvesting. All aspects are described from the conceptual considerations to technical realization and provide insight by detailed explanations, drawings, formulas, and example processes.

Author: Ramkrishna Sen
Publisher: CRC Press
ISBN: 1000044408
Category : Medical
Languages : en
Pages : 453

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Book Description
The application of Biotechnology dates back to the early era of civilization, when people first started to cultivate food crops. While the early applications are certainly still relevant, modern biotechnology is primarily associated with molecular biology, cloning and genetic engineering not only to increase the yield and to improve the quality of the crop but also its potential impact has touched upon virtually all domains of human interactions. Within the last 50 years, several key scientific discoveries revolutionized the biological sciences that facilitated the rapid growth of the biotechnology industry. 'Biotechnology and Biological Sciences III' contains the contributions presented at the 3rd International Conference on Biotechnology and Biological Sciences (BIOSPECTRUM 2019, Kolkata, India, 8-10 August 2019). The papers discuss various aspects of Biotechnology such as: microbial biotechnology, bioinformatics and drug designing, innovations in pharmaceutical industries and food processing industries, bioremediation, nano-biotechnology, and molecular-genetics, and will be of interest to academics and professionals involved or interested in these subject areas.