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Author: Nuno Vale Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110468751 Category : Science Languages : en Pages : 361
Book Description
Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.
Author: Nuno Vale Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110468751 Category : Science Languages : en Pages : 361
Book Description
Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.
Author: Paul F. Torrence Publisher: John Wiley & Sons ISBN: 9780471326335 Category : Science Languages : en Pages : 438
Book Description
How basic chemical ideas help advance the understanding and treatment of disease Biomedical Chemistry presents clear, concise coverage of the application of chemistry to drug discovery and determination of disease etiology, highlighting its role in the explosive growth of biotechnology and molecular biology. Through expert contributions from leading researchers in diverse fields, the book provides readers with an understanding of how fundamental chemical concepts are used in the development of novel approaches to the major problems in medicine today. The authors explain both the science and reasoning underlying each experimental approach, exploring cutting-edge developments in AIDS, cancer, alcoholism, Parkinson's disease, trypanosomiasis, emphysema, and malaria. Contemporary research problems discussed include: * Mechanism-based drug discovery * Design of new antitumor and antiviral agents * Targeting tumors using magnetic drug delivery * Antisense and antigene agents Easily accessible to anyone with a solid undergraduate background in chemistry, Biomedical Chemistry is an excellent resource for researchers in health-related fields as well as anyone seeking an overview of frontier topics in medicinal chemistry, organic chemistry, and biochemistry.
Author: Peter J. Cragg Publisher: Springer Science & Business Media ISBN: 9048125820 Category : Science Languages : en Pages : 267
Book Description
The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field. Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application of supramolecular principles to molecular diagnostics with a particular emphasis on the ‘receptor-relayreporter’ motif. Many of the examples chosen have clinical importance. The third section takes the clinical diagnostic theme further and demonstrates the therapeutic applications of supramolecular chemistry through photodynamic therapy, drug delivery, and the potential for synthetic peptides to form antibiotic tubes. The short epilogue considers the potential for supramolecular solutions to be found for further challenges in biomimetic and therapeutic chemistry.
Author: Martin Braddock Publisher: Royal Society of Chemistry ISBN: 1849732914 Category : Medical Languages : en Pages : 553
Book Description
The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. Medicinal chemists need to know the critical issues involved in using such chemical agents with regard to the biological applications - for instance - what properties are needed chemically and why? The topics covered in the book are: PET, SPECT, contrast agents, radioimaging/radionuclide conjugates, receptor mapping, small animal imaging (eg. WBAR - whole body autoradiography); photoinduced labelling, as well as chapters on the physical techniques used including: NMR, mass spectrometry and Xray. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.
Author: Hans-Jorg Schneider Publisher: Royal Society of Chemistry ISBN: 1849737827 Category : Science Languages : en Pages : 549
Book Description
Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications. Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes. This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.
Author: Gareth Thomas Publisher: Ellis Horwood Limited ISBN: 9780131316997 Category : Law Languages : en Pages : 631
Book Description
Using a straightforward and broad approach this book incorporates inorganic and organic chemistry at degree level. It covers fundamental vocabulary and philosophy of chemistry, basic organic chemistry and selected inorganic topics of interest to the natura
Author: Alan Schechter Publisher: Elsevier ISBN: 0323149898 Category : Science Languages : en Pages : 448
Book Description
The Impact of Protein Chemistry on the Biomedical Sciences focuses on the structure, function, and synthesis of proteins. This book examines the various approaches on how amino acids are polymerized in vitro, which involves the physical, chemical, immunological, enzymologic, biosynthetic, and organic synthetic techniques. Comprised of five parts encompassing 27 chapters, this book starts with an overview of Christian B. Anfinsen's role in the development of protein chemistry and the training of scientists who have advanced their experiences in his laboratory to pioneer in the field of biological and medical sciences. This text then examines the synthesis of albumin molecule in the bloodstream as it carries cystine, hematin, bilirubin, fatty acids, and aromatic compounds. Other chapters discuss the kinetic experiments of hydrogen exchange in aqueous solution between peptide molecules and solvent water. This text also introduces the reader to the lipoprotein–atherosclerosis connection by studying the metabolism of plasma lipoproteins. This book is a valuable source of information for biologists, chemical biologists, scientists, and students.
Author: Stephen Faulkner Publisher: Royal Society of Chemistry ISBN: 183916137X Category : Technology & Engineering Languages : en Pages : 310
Book Description
There have been many great advances in the field of biomedical imaging in recent years, with supramolecular chemistry playing a key role in the evolution of modern imaging techniques. Non-covalent supramolecular interactions are fundamental to countless biological processes, from host–guest binding to the stabilisation of complex structures. Supramolecular chemistry techniques can be employed to create probes that can be targeted to either exploit or disrupt these interactions, giving the potential for both diagnostic and therapeutic effects. Furthermore, in techniques such as contrast enhanced MRI, controlling the interactions between solvent molecules and the imaging agent is crucial to the development of the technique. With rapid growth in the synthesis and study of molecular imaging agents, the understanding of their associated techniques has sometimes lagged behind. Supramolecular Chemistry in Biomedical Imaging will fill this gap by clarifying the state of current understanding and the nature of the underlying problems inherent to addressing problems in biology. It will cover both the techniques used in imaging and the molecular and supramolecular systems used to exploit them. This publication targets academics coming to the field from mainstream supramolecular chemistry, research graduates and undergraduates interested in supramolecular chemistry, synthesis or imaging agents and imaging techniques for biomedical applications.
Author: Giorgia Pastorin Publisher: Pan Stanford Publishing ISBN: 9789814241687 Category : Medical Languages : en Pages : 0
Book Description
This book represents a critical evaluation of the most recent discoveries about carbon nanotubes and includes a cautious description of their impact on personal health and environmental pollution. It also offers an overview of the main research groups around the world which have been focusing their efforts on the exploitation of this intriguing material, with the purpose of inspiring young scientists to follow their pathway.
Author: Ravin Narain Publisher: John Wiley & Sons ISBN: 1118776372 Category : Science Languages : en Pages : 934
Book Description
Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. With its emphasis on synthesis, properties and applications, this book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials. Its detailed descriptions of methods make it possible for researchers to fabricate and take full advantage of bioconjugates for a broad range of applications. Moreover, the book sets the foundation for the development of new applications, including assays, imaging, biosensors, drug delivery, and diagnostics. Chemistry of Bioconjugates features contributions from an international team of leading experts and pioneers in the field. These contributions reflect the authors’ firsthand laboratory experience as well as a thorough review of the current literature. The book’s six sections examine: General methods of bioconjugation Polymer bioconjugates Organic nanoparticle-based bioconjugates Inorganic nanomaterial bioconjugates, including metals and metal oxides Cell-based, hydrogel/microgel, and glyco-bioconjugates Characterization, physico-(bio)chemical properties, and applications of bioconjugates This comprehensive exploration of bioconjugates includes discussions of polymers, dendrimers, lipids, nanoparticles, and nanotubes. References at the end of each chapter serve as a gateway to the most important original research findings and reviews in the field. By drawing together and analyzing all the latest chemical methods and research findings on the physico-chemical and biochemical properties of bioconjugates, Chemistry of Bioconjugates sheds new light on the significance and potential of bioconjugation. The book is recommended for organic and polymer chemists, biochemists, biomaterial scientists, carbohydrate chemists, biophysicists, bioengineers, and drug and gene delivery scientists.
Author: Nuno Vale
Author: Nuno Vale
Author: Paul F. Torrence
Author: Peter J. Cragg
Author: Martin Braddock
Author: Hans-Jorg Schneider
Author: Gareth Thomas
Author: Alan Schechter
Author: Stephen Faulkner
Author: Giorgia Pastorin
Author: Ravin Narain