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Author: Ilona Swiatkowska Publisher: Academic Press ISBN: 0128217421 Category : Science Languages : en Pages : 294
Book Description
Nearly all orthopaedic surgeons have implanted a cobalt-chromium hip, and most general practitioners have at least one patient with a cobalt-chromium prosthesis on their books. The recent worldwide controversy surrounding metal-on-metal bearings – and increasing concern over the use of metallic biomaterials in general – means that advice on how to manage patients with metal implants is of great interest to these professionals. Specifically, they want to know if there are any diagnostic tests that could be performed to gain clues about implant performance and the risk of local or systemic toxicity. Biomarkers of Hip Implant Function aims to bring together all established and promising new biomarkers and critically evaluate their clinical usefulness. Researchers will benefit from an updated, comprehensive view of the topic to identify underexplored areas. Orthopaedic surgeons and general practitioners will use the book to monitor implant performance and manage their patients. The work may also benefit engineers and joint implant manufacturers by guiding improvements in implant design, and be of interest to regulators and policymakers to inform guidelines on the follow-up of hip implant recipients. - Covers all established and candidate biomarkers of hip implant wear, periprosthetic infection, and toxicity - Summarises recent research into blood titanium levels associated with well-functioning and malfunctioning hip implants to aid implant revision decisions - Reviews over 50 cases of suspected systemic cobalt toxicity to raise awareness of its symptoms and clinical presentation, and guide investigations and treatment decisions
Author: Ilona Swiatkowska Publisher: Academic Press ISBN: 0128217421 Category : Science Languages : en Pages : 294
Book Description
Nearly all orthopaedic surgeons have implanted a cobalt-chromium hip, and most general practitioners have at least one patient with a cobalt-chromium prosthesis on their books. The recent worldwide controversy surrounding metal-on-metal bearings – and increasing concern over the use of metallic biomaterials in general – means that advice on how to manage patients with metal implants is of great interest to these professionals. Specifically, they want to know if there are any diagnostic tests that could be performed to gain clues about implant performance and the risk of local or systemic toxicity. Biomarkers of Hip Implant Function aims to bring together all established and promising new biomarkers and critically evaluate their clinical usefulness. Researchers will benefit from an updated, comprehensive view of the topic to identify underexplored areas. Orthopaedic surgeons and general practitioners will use the book to monitor implant performance and manage their patients. The work may also benefit engineers and joint implant manufacturers by guiding improvements in implant design, and be of interest to regulators and policymakers to inform guidelines on the follow-up of hip implant recipients. - Covers all established and candidate biomarkers of hip implant wear, periprosthetic infection, and toxicity - Summarises recent research into blood titanium levels associated with well-functioning and malfunctioning hip implants to aid implant revision decisions - Reviews over 50 cases of suspected systemic cobalt toxicity to raise awareness of its symptoms and clinical presentation, and guide investigations and treatment decisions
Author: Jawahar Paulraj Publisher: CRC Press ISBN: 1040106102 Category : Medical Languages : en Pages : 265
Book Description
Tribo-Behaviors of Biomaterials and Their Applications enables the reader to make an informed choice in the selection of biomaterials that aid the creation of safe and long-lasting surgical devices. Looking at metals, ceramics, and polymers with craniofacial, cardiovascular, spinal, dentistry, and orthopedic applications, this book is an essential guide to tribology in biomaterials. Handling wear within biodevices is a pressing issue due to the continuous friction and corrosion within the body. It is further complicated by the involvement of body fluids, which can lead to revision surgery to relieve pain. In order to lessen this, engineers can choose a biomaterial better suited to the application. Including detailed discussion of the properties of each biomaterial, this book covers the behaviors of implants, along with the methods and standards applied to devices. It has chapters on metals, ceramics, and polymers. It also covers body fluid lubrication and the physiological effects they have on implants, along with their tribo-corrosion behaviors. This book will be of interest to engineers and researchers in the field of biomechanical engineering, biomedical engineering, materials science, and manufacturing engineering, alongside all those researching tribology and nanocomposites.
Author: Ramesh C Gupta Publisher: Academic Press ISBN: 0128146567 Category : Medical Languages : en Pages : 1248
Book Description
Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. - Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers - Includes completely revised chapters, along with additional chapters on the newest developments in the field - Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure - Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more
Author: Peter A. Revell Publisher: Woodhead Publishing ISBN: 0128210834 Category : Technology & Engineering Languages : en Pages : 726
Book Description
The third edition of Joint Replacement Technology provides a thoroughly updated review of recent developments in joint replacement technology. Joint replacement is a standard treatment for joint degradation and has improved the quality of life of millions of patients. Collaboration between clinicians and researchers is critical to its continued success and to meet the rising expectations of patients and surgeons.This edition covers a range of updated and new content, ranging from chapters on materials analysis and selection, to methodologies and techniques used for joint replacement and clinical challenges of replacing specific joints. Key topics include tribological considerations and experiments; challenges in joint bearing surfaces; cementless fixation techniques; healing responses to implants. Clinical challenges and perspectives are covered with the aid of case studies.Thanks to its widespread collaboration and international contributors, Joint Replacement Technology, Third Edition is useful for materials scientists and engineers in both academia and the biomedical industry. Chemists, clinicians, and other researchers in this area will also find this text invaluable. - This third edition provides an updated comprehensive review of recent developments in joint replacement technology - Reviews a range of specific joints, biological and mechanical issues and fixation techniques - Includes revised and new content, such as sections on regulatory affairs, AI techniques and 3D printing
Author: James V. Bono Publisher: Springer Science & Business Media ISBN: 1461214068 Category : Medical Languages : en Pages : 660
Book Description
An in-depth understanding of a comprehensive approach to the management of radius fractures and their complications. The authors -- world renowned experts in the field -- present practical, clinical information from their extensive experience in the treatment of these fractures. Topics include the authors' classification as well as decision- making and tactics in the conservative and operative management of all types of radius fractures. Topics covered include: bending fractures of the metaphysis, shearing and compression fractures of the joint surface, avulsion fractures, radio-carpal fracture and dislocation, combined fractures, high velocity injury and malunions. In addition, chapters deal with surgical techniques and approach as well as with complications. With over 500 illustrations, this is the definitive volume on these challenging fractures, their complete treatment, and the management of complications.
Author: Phuc Van Pham Publisher: Springer ISBN: 3319401440 Category : Science Languages : en Pages : 316
Book Description
This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
Author: Trisha Peel Publisher: Springer ISBN: 3319652508 Category : Medical Languages : en Pages : 270
Book Description
This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.
Author: Asif M. Ilyas Publisher: Elsevier Health Sciences ISBN: 0323414613 Category : Medical Languages : en Pages : 345
Book Description
Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot & ankle, and sports medicine.
Author: Ilona Swiatkowska
Author: Ilona Swiatkowska
Author: Jawahar Paulraj
Author: Ramesh C Gupta
Author: Paul A. Banaszkiewicz
Author: Peter A. Revell
Author: James V. Bono
Author: Phuc Van Pham
Author: Javad Parvizi
Author: Trisha Peel
Author: Asif M. Ilyas