Biología molecular y genética humana PDF Download

Author: Juan Pelegrín Sánchez Marín
Publisher:
ISBN: 9788418763731
Category :
Languages : es
Pages : 77

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Author: Carlos María Romeo Casabona
Publisher: Universidad de Deusto
ISBN: 8498307430
Category : Science
Languages : es
Pages : 380

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Book Description
Este libro pretende ofrecer una visión de conjunto sobre los aspectos más significativos relacionados con la biología molecular, desde la perspectiva de las investigaciones sobre el genoma humano y de las aplicaciones clínicas y médico-legales a que están dando lugar aquéllas. Se abordan por diversos y cualificados especialistas españoles materias capitales como el desarrollo embrionario y las técnicas de reproducción asistida, los diagnósticos genéticos (preconcepcional, preimplantatorio y prenatal), el consejo genético y la terapia génica, así como los mecanismos de la herencia, las pruebas genéticas de la paternidad y la huella genética. Precede a estos capítulos una introducción a la biología molecular y un desarrollo de los objetivos del Proyecto Genoma Humano. Con dos glosarios se desea facilitar el acercamiento terminológico al profano. La obra va dirigida no sólo a especialistas en biología molecular y genética, sino también a médicos y a no iniciados interesados en otros aspectos de la materia (educadores, informadores, filósofos, moralistas, sociólogos, juristas, etc) con el fin de favorecer desde el rigor científico y una muy cuidada claridad expositiva las reflexiones que pueden suscitar los efectos sociales de las investigaciones sobre el genoma humano, algunos de los cuales son pincelados en la presentación de la obra.

Author: Carlos María Romeo Casabona
Publisher:
ISBN: 9788474853391
Category : Science
Languages : es
Pages : 357

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Book Description
Este libro pretende ofrecer una visión de conjunto sobre los aspectos más significativos relacionados con la biología molecular, desde la perspectiva de las investigaciones sobre el genoma humano y de las aplicaciones clínicas y médico-legales a que están dando lugar aquéllas. Se abordan por diversos y cualificados especialistas españoles materias capitales como el desarrollo embrionario y las técnicas de reproducción asistida, los diagnósticos genéticos (preconcepcional, preimplantatorio y prenatal), el consejo genético y la terapia génica, así como los mecanismos de la herencia, las pruebas genéticas de la paternidad y la huella genética. Precede a estos capítulos una introducción a la biología molecular y un desarrollo de los objetivos del Proyecto Genoma Humano. Con dos glosarios se desea facilitar el acercamiento terminológico al profano. La obra va dirigida no sólo a especialistas en biología molecular y genética, sino también a médicos y a no iniciados interesados en otros aspectos de la materia (educadores, informadores, filósofos, moralistas, sociólogos, juristas, etc) con el fin de favorecer desde el rigor científico y una muy cuidada claridad expositiva las reflexiones que pueden suscitar los efectos sociales de las investigaciones sobre el genoma humano, algunos de los cuales son pincelados en la presentación de la obra.

Author: Leonardo Héctor Rioja Peregrina
Publisher:
ISBN:
Category : Human genetics
Languages : es
Pages : 288

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Author:
Publisher: Academic Press
ISBN: 0080536417
Category : Science
Languages : en
Pages : 521

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Book Description
Human Molecular Genetics is a practical guide to the applications of molecular biology and genetics techniques to human cells. A wide range of experimental procedures for investigating human genes and genomes are presented.* * Mutation Detection in Human Genes - chemical mismatch cleavage, DNA mini-sequencing, SSCP method, RT-PCR, electrophoretic mobility shift assay (EMSA), protein truncation test, chromosome deletion analysis.* Gene Mapping, Cloning, Sequencing - gene linkage determination, large-capacity cloning system, cDNA isolation, differential display method, primer-based DNA sequencing.* Transcription: Promoters, Transcription Factors, mRNA, - promotor mutation analysis, transcription factor identification, mRNA-protein interaction characterization.* RNA Editing, Ribozymes, Antisense RNA-mammalian RNA editing assays, ribozymes as genetic tools, antisense RNA technology.* Genome Recombination, Amplification - recombination assays for mammalian cells, gene amplification measurement.* Receptors, Signal Transduction - intra-cellular receptor characterization, analysis of signal transduction genes.* The Mouse as a Model System for Human Molecular Genetics - mouse genome methods (mouse crosses, somatic cell hybrids, YACs), mouse model for cardiovascular disease.

Author: I. Rasko
Publisher: Springer Science & Business Media
ISBN: 9780412373404
Category : Medical
Languages : en
Pages : 436

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Book Description
This stimulating book bridges the gap between molecular biology and human genetics. Specifically written for medical students and human geneticists, it is a valuable guide to a rapidly moving field.

Author: A.R. Peacocke
Publisher: Springer
ISBN: 1489963170
Category : Medical
Languages : en
Pages : 194

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Book Description

Author: Liang Cheng
Publisher: Springer Science & Business Media
ISBN: 1597454052
Category : Medical
Languages : en
Pages : 784

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Book Description
This volume presents a useful and up-to-date handbook containing information relevant to the clinical practice of molecular genetic pathology. It features organized, detailed text on specific molecular genetic techniques. The volume provides a unique reference for the practicing pathologist and medical geneticist, as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.

Author: Edward J. Murray
Publisher: Humana Press
ISBN: 9780896032163
Category : Medical
Languages : en
Pages : 439

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Book Description
Biology is the study of living things. The classical approach might be described as holistic and descriptive, whereas the modern molecular - proach aims to be investigative, reductionist, and mechanistic . Genes contain all the information for the structure of all living things ; thus, the understanding of how genes are regulated is an important step toward understanding the nature of living things. The study of gene regulation has been made more tractable by the design of simple expe- mental models in which a single gene can be isolated from the milieu of the organism. The new science of molecular biology has introduced techniques that permit the design of such experimental models. In - sence, the genome of the organism is dissected in such a manner that specific genes may now be introduced into an appropriate cell line . Subsequent analysis of the proteins expressed from the genes under study results in the identification of the regulatory DNA sequences .

Author: Morris Goodman
Publisher: Springer
ISBN: 9781461587859
Category : Science
Languages : en
Pages : 466

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Book Description
In 1962 at the Burg Wartenstein Symposium on "Classification and Human Evolution," Emile Zuckerkandl used the term "molecular anthropology" to characterize the study of primate phylogeny and human evolution through the genetic information contained in proteins and polynucleotides. Since that time, our knowledge of molecular evolution in primates and other organisms has grown considerably. The present volume examines this knowledge especially as it relates to the phyletic position of Homo sapiens in the order Primates and to the trends which shaped the direction of human evolution. Participants from the disciplines of protein and nucleotide chemistry, genetics, statistics, paleon tology, and physical anthropology held cross-disciplinary discussions and argued some of the major issues of molecular anthropology and the data upon which these arguments rest. Chief among these were the molecular clock controversy in hominoid evolution; the molecular evidence on phylogenetic relationships among primates; the evolution of gene expression regulation in primates; the relationship of fossil and molecular data in the Anthropoidea and other pri mates; the interpretation of the adaptive significance of evolutionary changes; and, finally, the impact on mankind of studies in molecular anthropology. Most of the papers in this volume were presented in a preliminary form at Symposium No. 65 on "Progress in Molecular Anthropology" held at Burg Wartenstein, Austria, from July 25 to August 1, 1975. These papers were subsequently revised and some additional papers related to the theme of the symposium were also contributed to this volume.