Author: Alfonso Calvo González
Publisher: Elsevier Health Sciences
ISBN: 8413823404
Category : Medical
Languages : es
Pages : 624
Book Description
- Nueva edición del texto de Biología celular dirigido por el Dr. Alfonso Calvo y que cuenta con un gran número de colaboradores. EL Dr. Alfonso Calvo tiene una amplia carrera tanto como docente (profesor de Biología celular e Histología. Facultad de Medicina y Ciencias de la Salud de Navarra) como investigador. Su área de interés son los tumores sólidos y los biomarcadores y desempeña su labor en el CIMA (Navarra) y en la Facultad de Medicina de la Universidad de Navarra. - El texto se posiciona como un texto que cubre la asignatura de Biología celular tanto para el grado de Medicina como de Biomedicina y Ciencias biomédicas. En la nueva edición se sigue con la misma filosofía ya que se hace especial énfasis en el funcionamiento de los orgánulos celulares y de cómo cuando estos están alterados dan lugar a las diferentes patologías - Su enfoque claramente biomédico incluye también aspectos de patología celular y sus consecuencias en el origen de las enfermedades. - La obra cuenta con un total de 18 capítulos (cap 18 disponible solo en formato online); todos ellos se han renovado y actualizado en su totalidad si bien, los relativos a cáncer y terapias con células madre son los que han sufrido mayores cambios por ser un tema en constante estudio. - Incluye un extenso material online disponible a través de la plataforma de SC.es en el que se incluyen preguntas de autoevaluación, casos clínicos, problemas, presentaciones ppt y un grupo de 4 videos.
Biología celular biomédica
Author: Alfonso Calvo González
Publisher: Elsevier Health Sciences
ISBN: 8413823404
Category : Medical
Languages : es
Pages : 624
Book Description
- Nueva edición del texto de Biología celular dirigido por el Dr. Alfonso Calvo y que cuenta con un gran número de colaboradores. EL Dr. Alfonso Calvo tiene una amplia carrera tanto como docente (profesor de Biología celular e Histología. Facultad de Medicina y Ciencias de la Salud de Navarra) como investigador. Su área de interés son los tumores sólidos y los biomarcadores y desempeña su labor en el CIMA (Navarra) y en la Facultad de Medicina de la Universidad de Navarra. - El texto se posiciona como un texto que cubre la asignatura de Biología celular tanto para el grado de Medicina como de Biomedicina y Ciencias biomédicas. En la nueva edición se sigue con la misma filosofía ya que se hace especial énfasis en el funcionamiento de los orgánulos celulares y de cómo cuando estos están alterados dan lugar a las diferentes patologías - Su enfoque claramente biomédico incluye también aspectos de patología celular y sus consecuencias en el origen de las enfermedades. - La obra cuenta con un total de 18 capítulos (cap 18 disponible solo en formato online); todos ellos se han renovado y actualizado en su totalidad si bien, los relativos a cáncer y terapias con células madre son los que han sufrido mayores cambios por ser un tema en constante estudio. - Incluye un extenso material online disponible a través de la plataforma de SC.es en el que se incluyen preguntas de autoevaluación, casos clínicos, problemas, presentaciones ppt y un grupo de 4 videos.
Publisher: Elsevier Health Sciences
ISBN: 8413823404
Category : Medical
Languages : es
Pages : 624
Book Description
- Nueva edición del texto de Biología celular dirigido por el Dr. Alfonso Calvo y que cuenta con un gran número de colaboradores. EL Dr. Alfonso Calvo tiene una amplia carrera tanto como docente (profesor de Biología celular e Histología. Facultad de Medicina y Ciencias de la Salud de Navarra) como investigador. Su área de interés son los tumores sólidos y los biomarcadores y desempeña su labor en el CIMA (Navarra) y en la Facultad de Medicina de la Universidad de Navarra. - El texto se posiciona como un texto que cubre la asignatura de Biología celular tanto para el grado de Medicina como de Biomedicina y Ciencias biomédicas. En la nueva edición se sigue con la misma filosofía ya que se hace especial énfasis en el funcionamiento de los orgánulos celulares y de cómo cuando estos están alterados dan lugar a las diferentes patologías - Su enfoque claramente biomédico incluye también aspectos de patología celular y sus consecuencias en el origen de las enfermedades. - La obra cuenta con un total de 18 capítulos (cap 18 disponible solo en formato online); todos ellos se han renovado y actualizado en su totalidad si bien, los relativos a cáncer y terapias con células madre son los que han sufrido mayores cambios por ser un tema en constante estudio. - Incluye un extenso material online disponible a través de la plataforma de SC.es en el que se incluyen preguntas de autoevaluación, casos clínicos, problemas, presentaciones ppt y un grupo de 4 videos.
Three Dimensional Human Organotypic Models for Biomedical Research
Author: Fabio Bagnoli
Publisher: Springer Nature
ISBN: 3030624528
Category : Medical
Languages : en
Pages : 265
Book Description
This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
Publisher: Springer Nature
ISBN: 3030624528
Category : Medical
Languages : en
Pages : 265
Book Description
This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
Natural Products and Neuroprotection
Author: Cristina Angeloni
Publisher: MDPI
ISBN: 303936216X
Category : Science
Languages : en
Pages : 338
Book Description
Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.
Publisher: MDPI
ISBN: 303936216X
Category : Science
Languages : en
Pages : 338
Book Description
Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.
Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches
Author: Claudia Duran-Aniotz
Publisher: Frontiers Media SA
ISBN: 2889746070
Category : Science
Languages : en
Pages : 265
Book Description
Publisher: Frontiers Media SA
ISBN: 2889746070
Category : Science
Languages : en
Pages : 265
Book Description
Mitochondrial Communication in Physiology, Disease and Aging
Author: Nuno Raimundo
Publisher: Frontiers Media SA
ISBN: 2889459632
Category :
Languages : en
Pages : 135
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Publisher: Frontiers Media SA
ISBN: 2889459632
Category :
Languages : en
Pages : 135
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Cellular Respiration and Carcinogenesis
Author: Shireesh Apte
Publisher: Springer Science & Business Media
ISBN: 1597454354
Category : Science
Languages : en
Pages : 206
Book Description
Cellular Respiration and Carcinogenesis presents leading experts in the field as it informs the reader about both basic and recent research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This masterfully compiled text offers the reader a fundamental understanding about how oxygen sensing and/or availability, programmed cell death, immune recognition and response and glucose metabolism are intimately linked with the two major mechanism or pathways of cellular respiration; oxidative phosphorylation and glycolysis. The editors and contributing authors proficiently and unequivocally address the effects of dysfunction of the mitochondrial oxidative phosphorylation/glycolysis (cellular respiration) mechanisms and pathways on the development of cancer. While it remains true that there are no universal truths in cancer, Cellular Respiration and Carcinogenesis opens the dialogue that the etiology of cancer can usually be associated with, and significantly attributed to the failure of one or multiple pathways of oxidative phosphorylation (cellular respiration) to normally burn fuel to generate energy, vis-à-vis the Warburg hypothesis. Keeping with its cutting-edge nature, Cellular Respiration and Carcinogenesis provides the first glimpse to a cautionary evidence based counterbalance to the recent and rapidly proliferating notion that utilization of fuel primarily via glycolysis is a hallmark of cancer development.
Publisher: Springer Science & Business Media
ISBN: 1597454354
Category : Science
Languages : en
Pages : 206
Book Description
Cellular Respiration and Carcinogenesis presents leading experts in the field as it informs the reader about both basic and recent research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This masterfully compiled text offers the reader a fundamental understanding about how oxygen sensing and/or availability, programmed cell death, immune recognition and response and glucose metabolism are intimately linked with the two major mechanism or pathways of cellular respiration; oxidative phosphorylation and glycolysis. The editors and contributing authors proficiently and unequivocally address the effects of dysfunction of the mitochondrial oxidative phosphorylation/glycolysis (cellular respiration) mechanisms and pathways on the development of cancer. While it remains true that there are no universal truths in cancer, Cellular Respiration and Carcinogenesis opens the dialogue that the etiology of cancer can usually be associated with, and significantly attributed to the failure of one or multiple pathways of oxidative phosphorylation (cellular respiration) to normally burn fuel to generate energy, vis-à-vis the Warburg hypothesis. Keeping with its cutting-edge nature, Cellular Respiration and Carcinogenesis provides the first glimpse to a cautionary evidence based counterbalance to the recent and rapidly proliferating notion that utilization of fuel primarily via glycolysis is a hallmark of cancer development.
Archives of Medical Research
Assessments, Treatments and Modeling in Aging and Neurological Disease
Author: Colin R Martin
Publisher: Academic Press
ISBN: 0128180013
Category : Medical
Languages : en
Pages : 608
Book Description
Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. The book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain, including Alzheimer's, stroke and multiple sclerosis. - Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging - Features sections on diagnosis and biomarkers of neurological aging, Alzheimer's and stroke - Contains an abstract, key facts, a mini dictionary of terms, and summary points in each chapter - Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations - Includes more than 500 illustrations and tables
Publisher: Academic Press
ISBN: 0128180013
Category : Medical
Languages : en
Pages : 608
Book Description
Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. The book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain, including Alzheimer's, stroke and multiple sclerosis. - Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging - Features sections on diagnosis and biomarkers of neurological aging, Alzheimer's and stroke - Contains an abstract, key facts, a mini dictionary of terms, and summary points in each chapter - Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations - Includes more than 500 illustrations and tables
Biología celular biomédica
The Role of Glia in Alzheimer's Disease
Author: Beatriz G. Perez-Nievas
Publisher: Frontiers Media SA
ISBN: 2889457648
Category :
Languages : en
Pages : 128
Book Description
We believe that the role of glia is the next frontier to be explored in Alzheimer’s disease research. This eBook is an update on both the current knowledge of astrocytes and microglia involvement in Alzheimer’s disease pathophysiology, and some of the techniques available to study them.
Publisher: Frontiers Media SA
ISBN: 2889457648
Category :
Languages : en
Pages : 128
Book Description
We believe that the role of glia is the next frontier to be explored in Alzheimer’s disease research. This eBook is an update on both the current knowledge of astrocytes and microglia involvement in Alzheimer’s disease pathophysiology, and some of the techniques available to study them.