BIOCOMPATIBLE SUPERPARAMAGNETIC FERRITE NANOPARTICLES FOR TREATMENT OF CANCER BY HYPERTHERMIA PDF Download
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Author: Sarbjit Singh Publisher: Sarbjit Singh ISBN: 9785343743012 Category : Languages : en Pages : 0
Book Description
Biocompatible superparamagnetic ferrite nanoparticles are a type of nanotechnology that has shown great promise in the treatment of cancer by hyperthermia. These nanoparticles are typically composed of iron oxide and are superparamagnetic, meaning that they exhibit strong magnetic properties only when exposed to an external magnetic field. One of the key advantages of these nanoparticles is their biocompatibility, which means that they are non-toxic and do not harm healthy cells in the body. In cancer treatment, these nanoparticles can be designed to specifically target tumor cells, allowing for a more targeted and effective therapy. Hyperthermia treatment involves heating the tumor cells to temperatures above normal body temperature, which causes the cancer cells to die. The superparamagnetic properties of these nanoparticles make them particularly effective for this purpose, as they can be easily heated by exposure to an alternating magnetic field, thereby selectively killing cancer cells while sparing healthy cells. Furthermore, these nanoparticles can also be used for drug delivery, allowing for targeted delivery of chemotherapy agents directly to tumor cells. Overall, biocompatible superparamagnetic ferrite nanoparticles show great potential in the development of new and innovative cancer therapies. The word "nanomaterials" consists of two words i.e. nano and material. The size of materials whose dimensions are equal or less than 100 nm is said to be nanomaterial. These materials have been the subject of numerous investigations in the past two decades due to their unique properties and have a technological impact on future generation devices. It has been known that materials exhibit some remarkable properties at nanoscale those are different from its macro-scale size. There is a drastic change in physical, chemical, magnetic, electrical, optical, electronic, and mechanical properties which are further size-dependent. This happens due to unusual properties at nanoscale viz., large surface to volume ratio of atoms, quantum confinement, high chemical reactivity, presence of dangling bonds.
Author: Sarbjit Singh Publisher: Sarbjit Singh ISBN: 9785343743012 Category : Languages : en Pages : 0
Book Description
Biocompatible superparamagnetic ferrite nanoparticles are a type of nanotechnology that has shown great promise in the treatment of cancer by hyperthermia. These nanoparticles are typically composed of iron oxide and are superparamagnetic, meaning that they exhibit strong magnetic properties only when exposed to an external magnetic field. One of the key advantages of these nanoparticles is their biocompatibility, which means that they are non-toxic and do not harm healthy cells in the body. In cancer treatment, these nanoparticles can be designed to specifically target tumor cells, allowing for a more targeted and effective therapy. Hyperthermia treatment involves heating the tumor cells to temperatures above normal body temperature, which causes the cancer cells to die. The superparamagnetic properties of these nanoparticles make them particularly effective for this purpose, as they can be easily heated by exposure to an alternating magnetic field, thereby selectively killing cancer cells while sparing healthy cells. Furthermore, these nanoparticles can also be used for drug delivery, allowing for targeted delivery of chemotherapy agents directly to tumor cells. Overall, biocompatible superparamagnetic ferrite nanoparticles show great potential in the development of new and innovative cancer therapies. The word "nanomaterials" consists of two words i.e. nano and material. The size of materials whose dimensions are equal or less than 100 nm is said to be nanomaterial. These materials have been the subject of numerous investigations in the past two decades due to their unique properties and have a technological impact on future generation devices. It has been known that materials exhibit some remarkable properties at nanoscale those are different from its macro-scale size. There is a drastic change in physical, chemical, magnetic, electrical, optical, electronic, and mechanical properties which are further size-dependent. This happens due to unusual properties at nanoscale viz., large surface to volume ratio of atoms, quantum confinement, high chemical reactivity, presence of dangling bonds.
Author: Nanasaheb Thorat Publisher: Springer Nature ISBN: 3031372875 Category : Technology & Engineering Languages : en Pages : 274
Book Description
This book delves into the methods of synthesis and functionalization of superparamagnetic materials, offering a deep understanding of their properties and applications. It explores the behavioral study of these materials and provides valuable insights into their diverse applications across various fields. A dedicated section focuses on in vitro and in vivo assessment, toxicology considerations, and post-application aspects. Furthermore, the book summarizes the current development of superparamagnetic materials, including an overview of ongoing clinical trials.
Author: Costica Caizer Publisher: John Wiley & Sons ISBN: 1119754747 Category : Science Languages : en Pages : 512
Book Description
Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.
Author: Martin F. Desimone Publisher: Materials Research Forum LLC ISBN: 164490232X Category : Technology & Engineering Languages : en Pages : 322
Book Description
Magnetic nanoparticles (MNPs) have many applications in the biomedical field because of their non-toxicity, high chemical stability, and biocompatibility. They are used in DNA or protein separation, hyperthermia, tissue engineering, magnetic resonance imaging, cancer therapy, drug delivery, bone and dental repair, biosensors, etc. The book focuses on magnetic nanoparticles and coated nanoparticles (ferrites nanoparticles, bimetallic-magnetic nanoparticles, magnetic fluid); their synthesis, characterization, and in vivo or in vitro biomedical applications. Keywords: Iron Oxide Magnetic Nanomaterials, Magnetic Spinel Ferrite Nanoparticles, Magnetic Oxide Nanoparticles, Ferromagnetic Nickel Nanostructures, Cobalt Ferrite with Niobium Pentoxide, Hyperthermia, Oncologic Magnetic Thermotherapy, Cancer Therapy, Cancer Diagnosis, Drug Delivery. Immune System Related Diseases.
Author: Devashish Shrivastava Publisher: John Wiley & Sons ISBN: 1119127300 Category : Science Languages : en Pages : 897
Book Description
An authoritative guide to theory and applications of heat transfer in humans Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow. This important text is the vital resource that: Offers a reference book in the field of heating and cooling of tissue, and associated damage. Provides a comprehensive theoretical and experimental basis with biomedical applications Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures Includes simple examples and results so readers can use those results directly or adapt them for their applications Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.
Author: Piyush Kumar Publisher: Springer ISBN: 3319458264 Category : Technology & Engineering Languages : en Pages : 77
Book Description
This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chosen as the model system in this review. The authors give emphasis to multiple drug resistance (MDR) and its mechanism and how to overcome it using the nanoparticle approach.
Author: Pankaj Sharma Publisher: Springer Nature ISBN: 9819925835 Category : Ferrites (Magnetic materials) Languages : en Pages : 260
Book Description
This book edited by leading experts focuses on the foundation of ferrite materials since inception to its contemporary scenario including their vast applications. The contents range from the basic physics and chemistry of ferrites to its applications in telecommunication, SAR reduction, EMI shielding, hyperthermia treatment, and water decontamination. It also focuses on ferrite nanoparticles for sensing application, energy-storage applications, antimicrobial applications, corrosion protection applications, among others. This book is a useful reference to those in academia and industry.
Author: Gaurav Sharma Publisher: Materials Research Forum LLC ISBN: 1644901587 Category : Technology & Engineering Languages : en Pages : 378
Book Description
Ferrites are highly interesting high-tech materials. The book covers their classification, structure, synthesis, properties and applications. Emphasis is placed on biomedical applications, degradation of organic pollutants, high frequency applications, photocatalytic applications for wastewater remediation, solar cell applications, removal of organic dyes and drugs from aquatic systems, and the synthesis of hexagonal ferrites. Keywords: Ferrite, Spinel Ferrite Nanoparticles, Biomedical Applications, Ferrite Based Heterojunction, Photocatalytic Degradation of Organic Pollutants, Nickel-Zinc Ferrites, Spinel Ferrite Based Nanomaterials, Water Remediation, Magnetic Nano Particles, Wastewater Treatment, Piezo-Phototronic Effect, Ferrite Based Solar Cells, Aurivillius Based Ceramics, Hexagonal Ferrites.
Author: M.Heinrich Seegenschmiedt Publisher: Springer Science & Business Media ISBN: 3642578586 Category : Medical Languages : en Pages : 479
Book Description
Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.
Author: Sarbjit Singh
Author: Sarbjit Singh
Author: Nanasaheb Thorat
Author: Costica Caizer
Author: Martin F. Desimone
Author: Devashish Shrivastava
Author: Piyush Kumar
Author: Pankaj Sharma
Author: Gaurav Sharma
Author: M.Heinrich Seegenschmiedt
Author: Timothy Lee Kline