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Author: Gerald Litwack Publisher: Elsevier ISBN: 0323146163 Category : Technology & Engineering Languages : en Pages : 557
Book Description
Biochemical Actions of Hormones, Volume II is a 12-chapter text that surveys the significant developments toward understanding the primary effects of hormones in cellular receptors at the molecular level. This book starts with an overview of the genetic regulation by hormones and the role of cyclic adenosine monophosphate in hormonal response. These topics are followed by discussions on the hormone-dependent molecular mechanisms, which appear to participate in the regulation of cell proliferation and differentiation in this model system, as well as how multiple hormonal signals may serve to integrate a large number of complex regulatory mechanisms. A chapter deals with the comparative aspects of the physiology and biochemistry of insulin, with an emphasis on the molecular mode of action of insulin on metabolic processes. The remaining chapters deal with the physiology, mechanism of action, and biological effects of various hormones, including catecholamines, glucocorticoids, estrogens, progestins, gonadotropins, prolactin, adrenocorticotropic hormone, 25-hydroxycholecalciferol, and insect hormones. Endocrinologists will find this book invaluable.
Author: Gerald Litwack Publisher: Elsevier ISBN: 0323146163 Category : Technology & Engineering Languages : en Pages : 557
Book Description
Biochemical Actions of Hormones, Volume II is a 12-chapter text that surveys the significant developments toward understanding the primary effects of hormones in cellular receptors at the molecular level. This book starts with an overview of the genetic regulation by hormones and the role of cyclic adenosine monophosphate in hormonal response. These topics are followed by discussions on the hormone-dependent molecular mechanisms, which appear to participate in the regulation of cell proliferation and differentiation in this model system, as well as how multiple hormonal signals may serve to integrate a large number of complex regulatory mechanisms. A chapter deals with the comparative aspects of the physiology and biochemistry of insulin, with an emphasis on the molecular mode of action of insulin on metabolic processes. The remaining chapters deal with the physiology, mechanism of action, and biological effects of various hormones, including catecholamines, glucocorticoids, estrogens, progestins, gonadotropins, prolactin, adrenocorticotropic hormone, 25-hydroxycholecalciferol, and insect hormones. Endocrinologists will find this book invaluable.
Author: Gerald Litwack Publisher: Elsevier ISBN: 0323150268 Category : Science Languages : en Pages : 441
Book Description
Biochemical Actions of Hormones, Volume VII is a nine-chapter text that covers a broad range of subjects representing research efforts on hormone action. This book deals first with the developments on hormones of the thymus and the evidence on the regulation of liver steroid and drug metabolism by the hypothalamus and anterior pituitary. These topics are followed by discussions on the regulation by neurotransmitters in the hypothalamus of LHRH and somatostatin; the hormonal regulation of protein degradation in liver and in isolated cells; and the hormonal regulation of lipid mobilization from adipose tissue. Considerable chapters are devoted to steroid hormone mechanisms and the cell genetics of glucocorticoid responsiveness. The remaining chapters explore the mero-receptor and androgenic regulation in male accessory tissue. These chapters also highlight the molecular biological aspects of thyroid hormone action. This volume is an ideal source for biologists, biochemists, and researchers working in the subject and in related fields.
Author: Gerald Litwack Publisher: Elsevier ISBN: 0323146341 Category : Science Languages : en Pages : 550
Book Description
Biochemical Actions of Hormones, Volume XII is a compendium of papers discussing aspects of molecular biology with regard to hormone action and to certain hormone receptors. One paper discusses the different approaches and strategies that are used in determining the amino acid sequence. The paper also describes the structural organization of polyprotein precursors such as the peptide chemistry approach or the nucleic acid approach. Another paper investigates the regulation of prolactin biosynthesis by peptide hormones as a model for peptidergic regulation of gene expression. The paper defines in detail which components of the biosynthetic machinery are being regulated by the polypeptide hormones. One paper also analyzes the molecular biology of the metallothioneins, focusing on the glucocorticoid regulation of metallothioneins genes. Experiments show that when the mouse MT-I gene is activated in lymphoid cells, or transferred to other cells, it still retains information needed in metal-regulated expression, though glucocorticoids can no longer regulate the same gene. Other papers discuss the purification and properties of the nerve growth factor receptor, and the thyrotropin receptor. Micro-biologists, biochemists, molecular biologists, cellular biologists, endocrinologists, and scientists involved in cell research will find this collection valuable.
Author: Anthony W. Norman Publisher: Academic Press ISBN: 1483258106 Category : Science Languages : en Pages : 823
Book Description
Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.
Author: P Karlson Publisher: Elsevier ISBN: 1483267628 Category : Medical Languages : en Pages : 288
Book Description
Mechanisms of Hormone Action: A NATO Advanced Study Institute focuses on the action mechanisms of hormones, including regulation of proteins, hormone actions, and biosynthesis. The selection first offers information on hormone action at the cell membrane and a new approach to the structure of polypeptides and proteins in biological systems, such as the membranes of cells. Discussions focus on the cell membrane as a possible locus for the hormone receptor; gaps in understanding of the molecular organization of the cell membrane; and a possible model of hormone action at the membrane level. The text also ponders on insulin and regulation of protein biosynthesis, including insulin and protein biosynthesis, insulin and nucleic acid metabolism, and proposal as to the mode of action of insulin in stimulating protein synthesis. The publication elaborates on the action of a neurohypophysial hormone in an elasmobranch fish; the effect of ecdysone on gene activity patterns in giant chromosomes; and action of ecdysone on RNA and protein metabolism in the blowfly, Calliphora erythrocephala. Topics include nature of the enzyme induction, ecdysone and RNA metabolism, and nature of the epidermis nuclear RNA fractions isolated by the Georgiev method. The selection is a valuable reference for readers interested in the mechanisms of hormone action.
Author: Anthony Albanese Publisher: Elsevier ISBN: 0323145493 Category : Science Languages : en Pages : 575
Book Description
Newer Methods of Nutritional Biochemistry: With Applications and Interpretations, Volume II provides information pertinent to nutritional biochemistry, including the development in enzyme concepts and methodology. This book discusses the mechanisms of several inborn errors of metabolisms and explains the methods by which these errors may be detected. Organized into 11 chapters, this volume starts with an overview of the advantages of body compositional data that are useful in evaluating treatment effects associated with physiological or nutritional experiments. This text then delineates the detection of aberrations in the metabolism of tryptophan, which may be induced by pathological stress. Other chapters consider the impact of hormones on the utilization of several nutrients. This book discusses as well the utilization of the essential nutrients, including amino acids, biotin, folic acid, pantothenic acid, and fat-soluble vitamins. The final chapter deals with principles and methods of nutritional needs in humans. Biochemists, graduate students, and investigators in the life sciences will find this book useful.
Author: A.K. Roy Publisher: Springer Science & Business Media ISBN: 1461254825 Category : Science Languages : en Pages : 345
Book Description
Receptors and Gene Expression It is now more than three years since the last Meadow Brook Conference on Hormones, and a great deal has happened in the meantime. We have become comfortable with the totally unanticipated fact that the coding sequences of genes are in discontinuous arrangements and that the RNA transcribed from them must be extensively processed to form messenger RNA. We have also learned about the strategy of "mixing and matching" of genetic segments so that a small amount of DNA can go a long way in producing a huge variety of different proteins, as in the immunoglobulin system. The explosive effort directed toward DNA sequence analysis has led us to the conclusion that there are signals within the DNA that specify sites of transcription initiation and possibly sites for interacting with regulatory molecules such as hor mones and their receptors. The current intense interest in the structure of chromatin beyond the nucleosome-that is, the superstructural characteris tics of the genetic material-is finally yielding meaningful results that give promise for understanding the regulation of gene activity. ROBERT F. GOLDBERGER Preface Research on the molecular mechanism of steroid hormone action continues at an extraordinary pace and a great deal of progress has been made. Steroid hormones have been localized on target genes providing the long awaited evidence for the concept of a direct effect of the steroid-receptor complex on gene regulation. Purified steroid receptors have been dissected to identify different functional domains.
Author: P Karlson Publisher: Elsevier ISBN: 0323162193 Category : Science Languages : en Pages : 560
Book Description
Introduction to Modern Biochemistry, Fourth Edition provides a better understanding of the chemical background of biological phenomena. The book presents an introduction and a survey of the facts and concepts of biochemistry. The text is intended to be an instructional material. Topics of general importance, such as the generation and utilization of free energy, the role of genes in protein and enzyme synthesis, and the importance of the submicroscopic structure of the cell in biochemical reactions, are emphasized. No distinction between descriptive biochemistry and dynamic biochemistry are made, for the sake of simplicity and better comprehension of concepts presented in the book. Students, biochemists, biologists, pharmacists, and medical practitioners will find this book as a good reference.
Author: Gerald Litwack
Author: Gerald Litwack
Author: Gerald Litwack
Author: Gerald Litwack
Author: Anthony W. Norman
Author: P Karlson
Author: National Library of Medicine (U.S.)
Author: Gerald Litwack
Author: Anthony Albanese
Author: A.K. Roy
Author: P Karlson