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Author: Xiaohong Wang Publisher: Nova Science Publishers ISBN: 9781634829571 Category : Artificial organs Languages : en Pages : 0
Book Description
This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.
Author: Xiaohong Wang Publisher: Nova Science Publishers ISBN: 9781634829571 Category : Artificial organs Languages : en Pages : 0
Book Description
This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.
Author: Dimitrios Stamatialis Publisher: World Scientific ISBN: 9813223987 Category : Technology & Engineering Languages : en Pages : 346
Book Description
This book focusses on the development of biomedical membranes and their applications for (bio)artificial organs. It covers the state of art and main challenges for applying synthetic membranes in these organs. It also highlights the importance of accomplishing an integration of engineering with biology and medicine to understand and manage the scientific, industrial, clinical and ethical aspects of these organs.The compendium consists of 11 chapters, written by world renowned experts in the fields of membrane technology, biomaterials science and technology, cell biology, medicine and engineering. Every chapter describes the clinical needs and the materials, membranes, and concepts required for the successful development of the (bio)artificial organs.This text is suitable for undergraduate and graduate students in biomedical engineering, materials science and membrane science and technology, as well as, for professionals and researchers working in these fields.
Author: David Hunkeler Publisher: ISBN: Category : Medical Languages : en Pages : 440
Book Description
The presentations in this volume, resulting from the 2nd International Conference on Bioartificial Organs, are divided almost equally among medical practitioners and surgeons, materials scientists and engineers; presenters came from industry, academia and governmental organizations. Sections are dedicated to specific diseases and organ replacements, such as the bioartificial pancreas (diabetes). Clinical trials on the bioartificial liver and skin are presented as are new developments in the craniofacial and cartilage areas. There is discussion on tissue sourcing (xeno-and allografts) as well as on the suitability of the proposed xenotransplantation for immunoisolation devices. Advances in genetically modified cells are also highlighted. Sessions on the molecular aspects of rejection prevention, on new biomaterials, and on processing complement the plenary medical- and technology-oriented themes. A panel discussion on scale-up and commercial implementation rounds out the volume.
Author: Loredana De Bartolo Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110268019 Category : Medical Languages : en Pages : 274
Book Description
Membrane processes today play a signifi cant role in the replacement therapy for acute and chronic organ failure diseases. Current extracorporeal blood purifi cation and oxygenation devices employ membranes acting as selective barriers for the removal of endogeneous and exogeneous toxins and for gas exchange, respectively. Additionally, membrane technology offers new interesting opportunities for the design of bioartificial livers, pancreas, kidneys, lungs etc. This book reviews the latest developments in membrane systems for bioartificial organs and regenerative medicine, investigates how membrane technology can improve the quality and efficiency of biomedical devices, and highlights the design procedures for membrane materials covering the preparation, characterization, and sterilization steps as well as transport phenomena. The different strategies pursued for the development of membrane bioartifi cial organs, including crucial issues related to blood/cell-membrane interactions are described with the aim of opening new and exciting frontiers in the coming decades. The book is a valuable tool for tissue engineers, clinicians, biomaterials scientists, membranologists as well as biologists and biotechnologists. It is also a source of reference for students, academic and industrial researchers in the topic of biotechnology, biomedical engineering, materials science and medicine.
Author: Nihal Vrana Publisher: Woodhead Publishing ISBN: 0081029071 Category : Medical Languages : en Pages : 847
Book Description
Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations
Author: Anwarul Hasan Publisher: John Wiley & Sons ISBN: 3527338632 Category : Science Languages : en Pages : 762
Book Description
A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.
Author: L Hench Publisher: Elsevier ISBN: 1845690869 Category : Science Languages : en Pages : 298
Book Description
Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs. Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. Comprehensive introduction to living and man-made materials Looks at clinical applications of various biomaterials and devices Bioengineering principles, materials and designs used in artificial organs are summarised
Author: Giuseppe Orlando Publisher: Academic Press ISBN: 012398520X Category : Science Languages : en Pages : 1050
Book Description
Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions
Author: Xiaohong Wang
Author: Xiaohong Wang
Author: Dimitrios Stamatialis
Author: David Hunkeler
Author: Ales Prokop
Author: Loredana De Bartolo
Author: Nihal Vrana
Author: Loredana De Bartolo
Author: Anwarul Hasan
Author: L Hench
Author: Giuseppe Orlando