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Author: Miriam Zelditch Publisher: Wiley-Liss ISBN: Category : Medical Languages : en Pages : 400
Book Description
Heterochrony has been a dominant theme in the explosion of interest of evolution and development. This book explores beyond heterochrony for the links between evolutionary and developmental processes, as well as the origins of morphological diversity.
Author: Miriam Zelditch Publisher: Wiley-Liss ISBN: Category : Medical Languages : en Pages : 400
Book Description
Heterochrony has been a dominant theme in the explosion of interest of evolution and development. This book explores beyond heterochrony for the links between evolutionary and developmental processes, as well as the origins of morphological diversity.
Author: Michael L. McKinney Publisher: Springer Science & Business Media ISBN: 1475707738 Category : Science Languages : en Pages : 452
Book Description
The authors outline evolutionary thought from pre-Darwinian biology to current research on the subject. They broadly label the factors of evolution as intrinsic and extrinsic, with Darwin favoring the latter by emphasizing the process of natural selection and later followers of Darwin carrying t
Author: George E. Billman Publisher: Frontiers Media SA ISBN: 2889711668 Category : Science Languages : en Pages : 96
Book Description
This Research Topic eBook includes articles from Volume I and II of The Future of Physiology: 2020 and Beyond series: Research Topic “The Future of Physiology: 2020 and Beyond, Volume I” Research Topic “The Future of Physiology: 2020 and Beyond, Volume II” The term Physiology was introduced in the 16th century by Jean Francois Fernel to describe the study of the normal function of the body as opposed to pathology, the study of disease. Over the ensuing centuries, the concept of physiology has evolved and a central tenet that unites all the various sub-disciplines of physiology has emerged: the quest to understand how the various components of an organism from the sub-cellular and cellular domain to tissue and organ levels work together to maintain a steady state in the face of constantly changing and often hostile environmental conditions. It is only by understanding normal bodily function that the disruptions that leads to disease can be identified and corrected to restore the healthy state. During the summer of 2009, I was invited by Dr. Henry Markram, one of the founders of the “Frontiers In” series of academic journals, to serve as the Field Chief Editor and to launch a new Open-access physiology journal that would provide a forum for the free exchange of ideas and would also meet the challenge of integrating function from molecules to the intact organism. In considering the position, I needed to answer two questions: 1) What exactly is Open-access publishing?; and 2) What could Frontiers in Physiology add to the already crowded group of physiology related journals? As a reminder, the traditional model of academic publishing “is a process by which academic scholars provide material, reviewing, and editing expertise for publication, free of charge, then pay to publish their work” and, to add insult to injury, they and their colleagues must pay the publisher a fee (either directly or via an institutional subscription) to read their published work [slightly modified from the “The Devil’s Dictionary of Publishing” Physiology News (the quarterly newsletter of the Physiological Society) Spring 2019: Issue 114, page 8]. In the traditional model, the publisher, not the authors, owns the copyright such that the author must seek permission and may even be required to pay a fee to re-use their own material (such as figures) in other scholarly articles (reviews, book chapters, etc.). In contrast, individuals are never charged a fee to read articles published in open-access journals. Thus, scholars and interested laymen can freely access research results (that their tax dollars paid for!) even if their home institution does not have the resources to pay the often exorbitant subscription fees. Frontiers takes the open-access model one step further by allowing authors (rather than the publisher) to retain ownership (i.e., the copyright) of their intellectual property. Having satisfied the first question, I then considered whether a new physiology journal was necessary. At that point in time there were no open-access physiology journals, and further, many aspects of physiology were not covered in the existing journals. Frontiers afforded the unique opportunity to provide a home for more specialized sections under the general field journal, Frontiers in Physiology, with each section having an independent editor and editorial board. I therefore agreed to assume the duties of Field Chief Editor in November 2009. Frontiers in Physiology was launched in early 2010 and the first articles were published in April 2010. Since these initial publications, we have published over 10,000 articles and have become the most cited physiology journal. Clearly we must be fulfilling a critical need. Now that it has been over a decade since Frontiers in Physiology was launched, it is time to reflect upon what has been accomplished in the last decade and what questions and issues remain to be addressed. Therefore, it is the goal of this book to evaluate the progress made during the past decade and to look forward to the next. In particular, the major issues and expected developments in many of the physiology sub-disciplines will be explored in order to inspire and to inform readers and researchers in the field of physiology for the year 2020 and beyond. A brief summary of each chapter follows: In chapter 1, Billman provides a historical overview of the evolution of the concept of homeostasis. Homeostasis has become the central unifying concept of physiology and is defined as a self-regulating process by which a living organism can maintain internal stability while adjusting to changing external conditions. He emphasizes that homeostasis is not static and unvarying but, rather, it is a dynamic process that can change internal conditions as required to survive external challenges and can be said to be the very basis of life. He further discusses how the concept of homeostasis has important implications with regards to how best to understand physiology in intact organisms: the need for more holistic approaches to integrate and to translate this deluge of information obtained in vitro into a coherent understanding of function in vivo. In chapter 2, Aldana and Robeva explore the emerging concept of the holobiont: the idea that every individual is a complex ecosystem consisting of the host organism and its microbiota. They stress the need for multidisciplinary approaches both to investigate the symbiotic interactions between microbes and multicellular organisms and to understand how disruptions in this relationship contributes to disease. This concept is amplified in chapter 3 in which Pandol addresses the future of gastrointestinal physiology ,emphasizing advances that have been made by understanding the role that the gut microbiome plays in both health and in disease. Professor Head, in chapter 4, describes areas in the field of integrative physiology that remain to be examined, as well as the potential for genetic techniques to reveal physiological processes. The significant challenges of developmental physiology are enumerated by Burggren in chapter 5. In particular, he analyzes the effects of climate change (environmentally induced epigenetic modification) on phenotype expression. In chapter 6, Ivell and Annad-Ivell highlight the major differences between the reproductive system and other organ systems. They conclude that the current focus on molecular detail is impeding our understanding of the processes responsible for the function of the reproductive organs, echoing and amplifying the concepts raised in chapter 1. In chapter 7, Costa describes the role of both circadian and non-circadian biological “clocks” in health and disease, thereby providing additional examples of integrated physiological regulation. Coronel, in chapter 8, provides a brief history of the development of cardiac electrophysiology and then describes areas that require further investigation and includes tables that list specific questions that remain to be answered. In a similar manner, Reiser and Janssen (chapter 9) summarize some of the advancements made in striated muscle physiology during the last decade and then discuss likely trends for future research; to name a few examples, the contribution of gender differences in striated muscle function, the mechanisms responsible of age-related declines in muscle mass, and role of exosome-released extracellular vesicles in pathophysiology. Meininger and Hill describe the recent advances in vascular physiology (chapter 10) and highlight approaches that should facilitate our understanding of the vascular processes that maintain health (our old friend homeostasis) and how disruptions in these regulatory mechanisms lead to disease. They also stress the need for investigators to exercise ethical vigilance when they select journals to publish in and meetings to attend. They note that the proliferation of profit driven journals of dubious quality threatens the integrity of not only physiology but science in general. The pathophysiological consequences of diabetes mellitus are discussed in chapters 11 and 12. In chapter 11, Ecelbarger addresses the problem of diabetic nephropathy and indicates several areas that require additional research. In chapter 12, Sharma evaluates the role of oxidative damage in diabetic retinopathy, and then proposes that the interleukin-6-transsignaling pathway is a promising therapeutic target for the prevention of blindness in diabetic pateints. Bernardi, in chapter 13, after briefly reviewing the considerable progress that has been achieved in understanding mitochondrial function, lists the many questions that remain to be answered. In particular, he notes several areas for future investigation including (but not limited to) a more complete understanding of inner membrane permeability changes, the physiology of various cation channels, and the role of mitochondrial DNA in disease. In chapter 14, using Douglas Adam’s “The Hitchhikers Guide to the Universe” as a model, Bogdanova and Kaestner address the question why a young person should study red blood cell physiology and provide advice for early career scientists as they establish independent laboratories. They the, describe a few areas that merit further attention, not only related to red blood cell function, but also to understanding the basis for blood related disease, and the ways to increase blood supplies that are not dependent on blood donors. Finally, the last two chapters specifically focus on non-mammalian physiology. In chapter 15, Scanes asks the question, are birds simply feathered mammals, and then reviews several of the significant differences between birds and mammals, placing particular emphasis on differences in gastrointestinal, immune, and female reproductive systems. In the final chapter (chapter 16) Anton and co-workers stress that since some 95% of living animals species are invertebrates, invertebrate physiology can provide insights into the basic principles of animal physiology as well as how bodily function adapts to environmental changes. The future of Physiology is bright; there are many important and interesting unanswered questions that will require further investigation. All that is lacking is sufficient funding and a cadre of young scientists trained to integrate function from molecules to the intact organism. George E. Billman, Ph.D, FAHA, FHRS, FTPS Department of Physiology and Cell Biology The Ohio State University Columbus OH, United States
Author: Massimo Pigliucci Publisher: Oxford University Press, USA ISBN: 0195160436 Category : Developmental biology Languages : en Pages : 460
Book Description
The interface of evolution and development has attracted the attention of evolutionary and developmental biologists, geneticists, and organismal biologists. Pigliucci (ecology, evolutionary biology, University of Tennessee) and Preston (botany, Standford University) bring together work by experts in the field of phenotype integration, shedding ligh.
Author: J. L. Thompson Publisher: Cambridge University Press ISBN: 9781139442084 Category : Social Science Languages : en Pages : 474
Book Description
It is generally accepted that the earliest human ancestors grew more like apes than like humans today. If they did so, and we are now different, when, how and why did our modern growth patterns evolve? This book focuses on species within the genus Homo to investigate the evolutionary origins of characteristic human patterns and rates of craniofacial and postcranial growth and development, and to explore unique ontogenetic patterns within each fossil species. Experts examine growth patterns found within available Plio-Pleistocene hominid samples, and analyse variation in ontogenetic patterns and rates of development in recent modern humans in order to provide a comparative context for fossil hominid studies. Presenting studies of some of the newer juvenile fossil specimens and information on Homo antecessor, this book will provide a rich data source with which anthropologists and evolutionary biologists can address the questions posed above.
Author: Michael L. McKinney Publisher: Springer Science & Business Media ISBN: 1489907955 Category : Science Languages : en Pages : 353
Book Description
... an adult poet is simply an individual in a state of arrested development-in brief, a sort of moron. Just as all of us, in utero, pass through a stage in which we are tadpoles, ... so all of us pass through a state, in our nonage, when we are poets. A youth of seventeen who is not a poet is simply a donkey: his development has been arrested even anterior to that of the tadpole. But a man of fifty who still writes poetry is either an unfortunate who has never developed, intellectually, beyond his teens, or a conscious buffoon who pretends to be something he isn't-something far younger and juicier than he actually is. -H. 1. Mencken, High and Ghostly Matters, Prejudices: Fourth Series (1924) Where would evolution be, Without this thing, heterochrony? -M. L. McKinney (1987) One of the joys of working in a renascent field is that it is actually possible to keep up with the literature. So it is with mixed emotions that we heterochronists (even larval forms like myself) view the recent "veritable explosion of interest in heterochrony" (in Gould's words in this volume). On the positive side, it is ob viously necessary and desirable to extend and expand the inquiry; but one regrets that already we are beginning to talk past, lose track of, and even ignore each other as we carve out individual interests.
Author: Alan C. Love Publisher: Springer ISBN: 940179412X Category : Science Languages : en Pages : 492
Book Description
This volume explores questions about conceptual change from both scientific and philosophical viewpoints by analyzing the recent history of evolutionary developmental biology. It features revised papers that originated from the workshop "Conceptual Change in Biological Science: Evolutionary Developmental Biology, 1981-2011" held at the Max Planck Institute for the History of Science in Berlin in July 2010. The Preface has been written by Ron Amundson. In these papers, philosophers and biologists compare and contrast key concepts in evolutionary developmental biology and their development since the original, seminal Dahlem conference on evolution and development held in Berlin in 1981. Many of the original scientific participants from the 1981 conference are also contributors to this new volume and, in conjunction with other expert biologists and philosophers specializing on these topics, provide an authoritative, comprehensive view on the subject. Taken together, the papers supply novel perspectives on how and why the conceptual landscape has shifted and stabilized in particular ways, yielding insights into the dynamic epistemic changes that have occurred over the past three decades. This volume will appeal to philosophers of biology studying conceptual change, evolutionary developmental biologists focused on comprehending the genesis of their field and evaluating its future directions, and historians of biology examining this period when the intersection of ev olution and development rose again to prominence in biological science.
Author: Bruce H. Weber Publisher: MIT Press ISBN: 9780262232296 Category : Education Languages : en Pages : 360
Book Description
Essays on the contributions to historical and contemporary evolutionary theory of the Baldwin effect, which postulates the effects of learned behaviors on evolutionary change.
Author: Miriam Zelditch
Author: Miriam Zelditch
Author: Michael L. McKinney
Author: George E. Billman
Author: Glenn Seward Jaecks
Author: Massimo Pigliucci
Author: J. L. Thompson
Author: Isabel Rábano
Author: Michael L. McKinney
Author: Alan C. Love
Author: Bruce H. Weber