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Benzodiazepines and GHB

Benzodiazepines and GHB PDF Author: Salvatore J. Salamone
Publisher: Springer Science & Business Media
ISBN: 1592591094
Category : Medical
Languages : en
Pages : 157

Book Description
Prominent experts explain the pharmacology and metabolism of benzodiazepines (LDB) and g-hydroxybutyric acid (GHB) and offer powerful and effective methodologies that will enable better detection of these drugs in various body fluids, as well as in hair. The techniques include highly sensitive immunoassay detection of LDBs, the detection of Rohypnol® and other LDBs by mass spectrometry, and the ultrasensitive detection of GHB. State-of-the-art and highly practical, Benzodiazepines and GHB: Detection and Pharmacology offers toxicologists, forensic scientists, and clinical chemists today's most effective methods for detecting these widely abused drugs that are sometimes found associated with criminal acts.

Benzodiazepines and GHB

Benzodiazepines and GHB PDF Author: Salvatore J. Salamone
Publisher: Springer Science & Business Media
ISBN: 1592591094
Category : Medical
Languages : en
Pages : 157

Book Description
Prominent experts explain the pharmacology and metabolism of benzodiazepines (LDB) and g-hydroxybutyric acid (GHB) and offer powerful and effective methodologies that will enable better detection of these drugs in various body fluids, as well as in hair. The techniques include highly sensitive immunoassay detection of LDBs, the detection of Rohypnol® and other LDBs by mass spectrometry, and the ultrasensitive detection of GHB. State-of-the-art and highly practical, Benzodiazepines and GHB: Detection and Pharmacology offers toxicologists, forensic scientists, and clinical chemists today's most effective methods for detecting these widely abused drugs that are sometimes found associated with criminal acts.

Benzodiazepines and Ghb

Benzodiazepines and Ghb PDF Author: Salvatore J. Salamone
Publisher:
ISBN: 9781468496475
Category :
Languages : en
Pages : 164

Book Description


Review of

Review of PDF Author: BK. Logan
Publisher:
ISBN:
Category : Benzodiazepines
Languages : en
Pages : 1

Book Description
As the publisher's cover notes on this volume point out, the low dose benzodiazepines and gamma hydroxybutyrate (GHB) escape detection in many laboratories because of their low effective doses and rapid metabolism. This is an important shortcoming because of the forensic consequences of the use and misuse of these drugs. Edited by Dr. Salvatore Salamone, the book is a collection of seven papers, any of which would be at home in the pages of this Journal, and it will be a useful addition to the library of any laboratory looking to improve its performance in the areas discussed. Its focus, however, is on a few of the low dose benzodiazepines, (a fact not clear from the title), and includes only a single chapter on GHB.

Seminars in Addiction Psychiatry

Seminars in Addiction Psychiatry PDF Author: Ed Day
Publisher: Cambridge University Press
ISBN: 1911623184
Category : Medical
Languages : en
Pages : 311

Book Description
Comprehensive coverage of the theory, practical understanding and management of the psychiatric aspects of drug and alcohol use and dependence.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Addiction

Addiction PDF Author: David Nutt
Publisher: Oxford University Press, USA
ISBN: 0199685703
Category : Medical
Languages : en
Pages : 102

Book Description
An essential reference for psychiatrists, clinical psychologists, trainees, and specialist nurses, as well as primary care physicians/GPs with a special interest in mental health conditions and other healthcare professionals.

Absolute Addiction Psychiatry Review

Absolute Addiction Psychiatry Review PDF Author: Carla Marienfeld
Publisher: Springer Nature
ISBN: 303033404X
Category : Medical
Languages : en
Pages : 376

Book Description
This book serves as a tool for general psychiatrists, medical students, residents, and fellows looking for a clinically relevant and high-yield overview of addiction psychiatry in preparation for their board exams – or for everyday clinical practice. Written by expert educators in addiction psychiatry, the text is organized by substances misused and populations affected. This book serves as both a primary learning tool for those new to the field, as well as a reference for those working in addiction treatment. Each chapter begins with summaries of high yield clinical pearls, followed by general information including treatment, and then ends with accompanying board-style review questions. The scope includes understanding substances of misuse and substance use disorders (SUDs), how to evaluate, diagnose, and monitor SUDs, how to treat SUDs both pharmacologically and behaviorally, and critical information for specific populations of patients. Absolute Addiction Psychiatry for Clinical Practice and Review is an excellent resource for all medical students, residents, fellows, and professionals taking certification exams in addiction, including those in psychiatry, addiction medicine, emergency medicine, internal medicine, pain medicine, and others. The chapter "Laboratory Testing for Substance Use Disorders" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Toxicological Aspects of Drug-Facilitated Crimes

Toxicological Aspects of Drug-Facilitated Crimes PDF Author: Pascal Kintz
Publisher: Elsevier
ISBN: 0124169694
Category : Social Science
Languages : en
Pages : 307

Book Description
Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology. Brings together the latest research on the toxicological analysis of drug-facilitated crimes (DFC), with real-life case studies Provides up-to-date analytical techniques for determining toxicity levels in blood, urine, and hair Covers all types of toxicants involved in DFC, including alcohol, cannabis, MDMA, and a wide variety of pharmaceuticals

Club Drugs and Novel Psychoactive Substances

Club Drugs and Novel Psychoactive Substances PDF Author: Owen Bowden-Jones
Publisher: Cambridge University Press
ISBN: 1911623095
Category : Medical
Languages : en
Pages : 141

Book Description
Emerging illicit drugs pose a significant clinical challenge. This handbook offers an engaging, concise guide to managing these challenges.

The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology

The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology PDF Author: Simona Pichini
Publisher: Frontiers Media SA
ISBN: 2889459721
Category :
Languages : en
Pages : 107

Book Description
New Synthetic Opioids (NSOs), most of which are illegally produced and sold for recreational use, are posing a serious threat to the health of consumers. Due to the low cost of materials and equipment required for clandestine laboratories production with respect to the production cost of heroin, NSOs are climbing the illegal street and web drug market. Several of these drugs have been involved in a recent rise in acute intoxications and overdose deaths. Since NSOs offer enormous profit potential, and there is strong demand for their use, these drugs are being trafficked by organized crime and present major challenges for medical professionals facing intoxications and fatalities, law enforcement agencies fighting against their diffusion and policymakers trying to restrain the use and abuse of NSOs. This Research Topic aimed to fill the gap on current knowledge on pharmacology and toxicology, health risks for adult and newborns of NSOs covering both basic scientific as well as epidemiological and clinical aspects. 3 reviews, 3 mini-reviews, 1 original article, 2 case reports and 1 opinion are here presented.