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Author: Ian Hindmarch Publisher: Springer Science & Business Media ISBN: 3642732887 Category : Medical Languages : en Pages : 322
Book Description
The following papers were presented at an international workshop on benzo diazepine receptor ligands, memory and information processing, held during the 15th CINP meeting in Puerto Rico in December 1986 and organised by the editors and T. Roth. This workshop was aimed at reviewing and reflecting on past experience with benzodiazepines, evaluating the current state of knowledge of the actions of psychotropic orugs (particularly benzodiazepines, fJ-carbolines and benzodiazepine antagonists), and laying a basis of interest and speculation for future research into the potential use of these drugs in disorders of memory and information processing. There is much published material regarding the theoretical underpinnings of what psychologists call "memory", and doubtless there will be several more libraries filled with theses on the topic before a consensus is reached as regards basic definitions or even meaningful distinctions between for example, "short" and "long"-term memory - everyone has his own particular theory. The qualitative and quantitative diversity of the different approaches might seem to present an insurmountable problem for the psychologist seeking a unified conceptual framework. In practice the various theories produce a plethora of pragmatic and experimental techniques for psychopharmacologists and clinicians to use when investigating drugs with putative amnestic or promnestic properties.
Author: Ian Hindmarch Publisher: Springer Science & Business Media ISBN: 3642732887 Category : Medical Languages : en Pages : 322
Book Description
The following papers were presented at an international workshop on benzo diazepine receptor ligands, memory and information processing, held during the 15th CINP meeting in Puerto Rico in December 1986 and organised by the editors and T. Roth. This workshop was aimed at reviewing and reflecting on past experience with benzodiazepines, evaluating the current state of knowledge of the actions of psychotropic orugs (particularly benzodiazepines, fJ-carbolines and benzodiazepine antagonists), and laying a basis of interest and speculation for future research into the potential use of these drugs in disorders of memory and information processing. There is much published material regarding the theoretical underpinnings of what psychologists call "memory", and doubtless there will be several more libraries filled with theses on the topic before a consensus is reached as regards basic definitions or even meaningful distinctions between for example, "short" and "long"-term memory - everyone has his own particular theory. The qualitative and quantitative diversity of the different approaches might seem to present an insurmountable problem for the psychologist seeking a unified conceptual framework. In practice the various theories produce a plethora of pragmatic and experimental techniques for psychopharmacologists and clinicians to use when investigating drugs with putative amnestic or promnestic properties.
Author: Paul Willner Publisher: Cambridge University Press ISBN: 9780521391924 Category : Medical Languages : en Pages : 564
Book Description
Behavioural models in psychopharmacology are used for different purposes. The main concern of industrial psychopharmacologists is specifically to develop new and improved drugs for the treatment of mental disorders, while basic scientists use animal models to investigate the underlying nature of such conditions. The important distinction between these different perspectives is made explicit for the first time in this book. By considering such conditions as anxiety, depression, mania and schizophrenia, feeding disorders, dementia, and drug dependence, this book provides a comprehensive and critical review of the adequacy of the behavioural procedures used by psychopharmacologists to model psychiatric disorders. Graduate students and research workers in pscyhopharmacology, from both academic and industrial spheres, as well as clinicians, will find this book of considerable interest.
Author: Michel Hamon Publisher: John Libbey Eurotext ISBN: 9782742000180 Category : Medical Languages : en Pages : 244
Book Description
Although everybody had and will experience anxiety, its intensity, frequency and characteristics may vary from what can be considered as "normal" to pathological. The development of benzodiazepine as anxiolytics has been a major step firstly in therapeutics and secondly in the understanding of the associated biological mechanisms. Recently, new drugs without secondary effects of benzodiazepines have been developed. The purpose of the book was to take stock of the present knowledge: clinical aspects of pathological anxiety, neurobiological mechanisms associated with stress and anxiety, molecular targets of potent anxiolytic drugs, new issues and directions.
Author: David N. Stephens Publisher: Springer Science & Business Media ISBN: 3642784518 Category : Medical Languages : en Pages : 223
Book Description
Since the discovery some 15 years ago of benzodiazepine modulatory sites associated with GABA A receptors, great effort has gone into understanding their molecular pharmacology and into developing new anxiolytic drugs that interact selectively with them. Prominent in this research has beenthe discovery that ~-carbolines, a different chemical class from benzodiazepines, also act at these receptors but that their effects are sometimes quite different from those of the benzodiazepines.This book documents the latest discoveries in the molecular biology of the GABA A receptor and reveals how an integration of the results of research inmolecular biology, synthetic chemistry, biochemical and behavioral pharmacology, and clinical pharmacology has paved the way forthe development of ~-carbolines from substances inducing anxiety and convulsions to a novel therapy for anxiety states, achieving a behavioral selectivity through selective actions at subtypes of receptors.
Author: Alan D. Baddeley Publisher: Psychology Press ISBN: 9780863774317 Category : Psychology Languages : en Pages : 496
Book Description
The models of how human memory works and developments in our understanding of the subject are explained and examined in this textbook for students and professionals. The author has tried to keep the style accessible for the general reader too
Author: BUTCHER Publisher: Springer Science & Business Media ISBN: 1461598435 Category : Medical Languages : en Pages : 375
Book Description
JAMES L. MCGAUGH Understanding of the nature and functions of neurotransmitter systems in the brain has increased enormously in recent decades. Lack of knowledge required us, not too long ago, to use the adjective "putative" when discussing transmitters. Such caution is no longer essential (at least for a number of transmitters). Impressive progress has been achieved in understanding the pharmacology, biochemistry and anatomy of transmitter systems. There has, however, been relatively less progress in understanding the functioning of brain transmitters in regulating and mediating behavior. A simple and certainly correct explanation for this is, of course, that understanding of neurotransmitter functions requires prior detailed knowledge of basic pharmacology, biochemistry and anatomy. Beyond that, it now seems likely that progress in understanding the functions of brain neurotransmitters will proceed only as we examine the interactions of neurotransmitter systems in regulating behavioral functions. This premise is, of course, suggested by the findings of studies of the chemical neuroanatomy of the brain: Neurotransmitter systems are influenced by other neurotransmitter systems and, in tum, influence the same as well as other systems. No system works alone. The chapters in this book explicitly examine the interactions of neurotransmitter systems involved in the regulation of cognitive processes. The facts and interpretations offered provide compelling support for the premise that cognitive processes are orchestrated by interactions among neurotransmitter systems. And, they offer promise that understanding of such interactions will be of critical importance in the develop ment of treatments for brain diseases affecting cognitive functioning.
Author: K. Meier-Ewert Publisher: Springer Science & Business Media ISBN: 1489902457 Category : Medical Languages : en Pages : 208
Book Description
Sleep-wake disorders frequently give rise to severe ailments and varied distresses in a great number of people in the world, disturbing their physical and mental activities and their social function. Sleep-wake disorders are now classified into a great number of cate gories according to their clinical features and etiological factors. Patients with sleep-wake disorders are taken care of not only by specialists for such disorders but also by general physicians and specialists of different physical and mental disorders. In the recent years, the nature of sleep and sleep-wake disorders have been intensively studied by investiga tors belonging to different fields of science including medicine, biology, and psychology in many countries. It is very important for the progress of research that investigators work ing in the related fields in different countries meet together and exchange their findings and ideas. The Japanese-German International Symposium on Sleep-Wake Disorders was held on October 9-10th, 1996 in the old, beautiful city of Erfurt (Germany). This symposium was organized by Professor Karlheinz Meier-Ewert (Schwalmstadt, Germany) and Dr. Masako Okawa (Ichikawa, Japan), with support of the German Society of Sleep Research (President at that time, Professor J. H. Peter) and of the Japanese Society of Sleep Research (President at that time, Professor Y. Hishikawa).
Author: Ian Hindmarch
Author: Ian Hindmarch
Author: Ian Hindmarch
Author: Paul Willner
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Author: Michel Hamon
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Author: David N. Stephens
Author: Alan D. Baddeley
Author: BUTCHER
Author: K. Meier-Ewert