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Author: W. E. Crusio Publisher: ISBN: Category : Behavior genetics Languages : en Pages : 0
Book Description
"The first volume in the new Cambridge Handbooks in Behavioral Genetics, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically-modified or pharmacologically-treated animals, and in the interpretation and analyses of the results obtained. Offering a comprehensive overview of the genetics of naturally-occurring variation in mouse behavior; from perception and spontaneous behaviors, such as exploration, aggression, social interactions and motor behaviors to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike"--
Author: W. E. Crusio Publisher: ISBN: Category : Behavior genetics Languages : en Pages : 0
Book Description
"The first volume in the new Cambridge Handbooks in Behavioral Genetics, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically-modified or pharmacologically-treated animals, and in the interpretation and analyses of the results obtained. Offering a comprehensive overview of the genetics of naturally-occurring variation in mouse behavior; from perception and spontaneous behaviors, such as exploration, aggression, social interactions and motor behaviors to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike"--
Author: Wim E. Crusio Publisher: Cambridge University Press ISBN: 1107355575 Category : Science Languages : en Pages : 361
Book Description
The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Author: Byron C. Jones Publisher: CRC Press ISBN: 9781420048384 Category : Science Languages : en Pages : 416
Book Description
Neurobehavioral Genetics: Methods and Applications covers classic and contemporary approaches to the study of the brain and behavior, including basic and clinical research. This book is designed as a reference for investigators wishing to incorporate genetic methods into neurobehavioral research. A broad spectrum of methods are integrated, unlike any other publication currently in print. Neurobehavioral Genetics: Methods and Applications presents different models, from invertebrates to genetically defined mammals. Introductory chapters demonstrate the scope and power of genetic methods that can be applied to neurobehavioral research from statistical methods and linkage analysis to contemporary molecular genetic approaches to search for candidate genes. The second half of the book covers the applications of quantitative and molecular genetics in basic and clinical research. Topics covered include animal behavior and neurobiology and human clinical problems including neurodegenerative diseases and psychiatric disorders.
Author: Valter Tucci Publisher: John Wiley & Sons ISBN: 1118540719 Category : Medical Languages : en Pages : 648
Book Description
The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.
Author: Jacqueline N. Crawley Publisher: John Wiley & Sons ISBN: 0470119047 Category : Science Languages : en Pages : 544
Book Description
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.
Author: Peter Driscoll Publisher: Birkhauser ISBN: Category : Medical Languages : en Pages : 338
Book Description
Provides information on the increasing use of animal models by both academic and commercial scientists to investigate human genetic conditions that affect behavior, such as narcolepsy, epilepsy, alcohol intoxication, nicotine reaction, aggression and violence in males, and endogenous depression. Other conditions discussed include Down syndrome, Krabbe disease, and myelin disorders. Most of the experiments reported were on mice or rats. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Gene S. Fisch Publisher: Springer Science & Business Media ISBN: 1592593534 Category : Medical Languages : en Pages : 428
Book Description
A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfunction. The authors review the current status of research in autosomal disorders that produce cognitive-behavioral dysfunction and syndromal and nonsyndromal disorders that produce mental retardation.
Author: Susanna Pietropaolo Publisher: Cambridge University Press ISBN: 131606140X Category : Science Languages : en Pages : 471
Book Description
The second volume of Behavioral Genetics of the Mouse provides a comprehensive overview of the major genetically modified mouse lines used to model human neurobehavioral disorders: from disorders of perception, of autonomous and motor functions to social and cognitive syndromes, drug abuse and dependence as well as neurodegenerative pathologies. Mouse models obtained with different types of genetic manipulations (i.e. transgenic, knockout/in mice) are described in their pathological phenotypes, with a special emphasis on behavioral abnormalities. The major results obtained with many of the existing models are discussed in depth highlighting their strengths and limitations. A lasting reference, the thorough reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Author: W. E. Crusio
Author: W. E. Crusio
Author: Wim E. Crusio
Author: Wim E. Crusio
Author: Byron C. Jones
Author: Valter Tucci
Author: Jacqueline N. Crawley
Author: Peter Driscoll
Author: Gene S. Fisch
Author: Dongnhu Thuy Truong
Author: Susanna Pietropaolo