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Behavioral Clinical Trials for Chronic Diseases

Behavioral Clinical Trials for Chronic Diseases PDF Author: Lynda H. Powell
Publisher: Springer Nature
ISBN: 3030393305
Category : Psychology
Languages : en
Pages : 324

Book Description
This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.

Behavioral Clinical Trials for Chronic Diseases

Behavioral Clinical Trials for Chronic Diseases PDF Author: Lynda H. Powell
Publisher: Springer Nature
ISBN: 3030393305
Category : Psychology
Languages : en
Pages : 324

Book Description
This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.

Quality of Life in Behavioral Medicine Research

Quality of Life in Behavioral Medicine Research PDF Author: Joel E. Dimsdale
Publisher: Psychology Press
ISBN: 131784386X
Category : Psychology
Languages : en
Pages : 307

Book Description
The number of, and interest in, quality of life studies has grown dramatically in the last decade. On an ever increasing basis, patients, clinicians, researchers, and health policy regulators are considering quality of life in assessing treatment alternatives. Unfortunately, most discussions of quality of life are narrow in scope -- applying to only one disease group. This unique book represents the concerted effort of experts in academia, federal government health care regulators, and pharmaceutical industry representatives to define the promise and the problems associated with quality of life studies. The issues covered range from cross cutting ones to those that are specific to particular illnesses. Because quality of life takes into consideration such domains as mood, vocation, family, sexual functioning, social participation, and costs, this book will serve as an invaluable companion to readers with an interest in behavioral medicine research.

New Research Frontiers in Behavioral Medicine

New Research Frontiers in Behavioral Medicine PDF Author: Susan J. Blumenthal
Publisher: National Institutes of Health National
ISBN:
Category : Behavioral Medicine
Languages : en
Pages : 288

Book Description


Chronic Physical Disorders

Chronic Physical Disorders PDF Author: Alan Christensen
Publisher: John Wiley & Sons
ISBN: 0470692782
Category : Psychology
Languages : en
Pages : 312

Book Description
In Chronic Physical Disorders, the most prominent figures in the field of behavioral medicine argue why a biopsychosocial perspective is crucial to reducing the tremendous personal and societal burden of chronic disease.

Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease

Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309462568
Category : Medical
Languages : en
Pages : 335

Book Description
Since 1938 and 1941, nutrient intake recommendations have been issued to the public in Canada and the United States, respectively. Currently defined as the Dietary Reference Intakes (DRIs), these values are a set of standards established by consensus committees under the National Academies of Sciences, Engineering, and Medicine and used for planning and assessing diets of apparently healthy individuals and groups. In 2015, a multidisciplinary working group sponsored by the Canadian and U.S. government DRI steering committees convened to identify key scientific challenges encountered in the use of chronic disease endpoints to establish DRI values. Their report, Options for Basing Dietary Reference Intakes (DRIs) on Chronic Disease: Report from a Joint US-/Canadian-Sponsored Working Group, outlined and proposed ways to address conceptual and methodological challenges related to the work of future DRI Committees. This report assesses the options presented in the previous report and determines guiding principles for including chronic disease endpoints for food substances that will be used by future National Academies committees in establishing DRIs.

Sensory Science and Chronic Diseases

Sensory Science and Chronic Diseases PDF Author: Paule Valery Joseph
Publisher: Springer Nature
ISBN: 3030862828
Category : Medical
Languages : en
Pages : 259

Book Description
The textbook provides an overview of the sensory science field in the context of diseases such as obesity and Coronavirus disease 2019 (COVID-19). This book brings a summary of the state of the science in key areas and provides examples of translational science from using cellular and rodent models to human clinical trials and community health. The volume structure leads the reader through the physiology of taste and smell into how sensory testing for taste and smell is studied, basic mechanisms, various protocols that are used throughout the field along with the pros/cons of the current methods used. This resource is intended for classroom teaching, for novice researchers in sensory research as well as students and postdoctoral fellows. Example of courses are nutrition, basic nursing, interdisciplinary health courses, sensory perception (psychology), neuroscience, and medical courses, dentistry, food science and others.

Self-management of Chronic Disease

Self-management of Chronic Disease PDF Author: Kenneth A. Holroyd
Publisher:
ISBN:
Category : Chronic diseases
Languages : en
Pages : 648

Book Description


Promoting Adherence to Medical Treatment in Chronic Childhood Illness

Promoting Adherence to Medical Treatment in Chronic Childhood Illness PDF Author: Dennis Drotar
Publisher: Psychology Press
ISBN: 1135666415
Category : Psychology
Languages : en
Pages : 567

Book Description
Based on a conference that assembled experts in the field of pediatric compliance in chronic illness, this book presents the latest data and conceptual models of adherence to treatment and recommendations for new directions in the field. Interdisciplinary in approach, the contributors represent a broad array of disciplines, including anthropology, pediatrics, psychology, and sociology. Designed to address critical gaps in the understanding of adherence/compliance to treatment regiments for children with chronic health conditions, this book reviews: *conceptual models used to define adherence treatment and conduct research; *the influences on treatment adherence to chronic illness in children; *the impact of adherence to treatment on children's health and psychological development; *strategies of interventions to promote adherence and reduce noncompliance rates; *methodological and measurement problems in the assessment of treatment adherence; and *recommended research priorities for the measurement of adherence and applications of interventions and training in the treatment of pediatric chronic illness.

The Role of Purchasers and Payers in the Clinical Research Enterprise

The Role of Purchasers and Payers in the Clinical Research Enterprise PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309182905
Category : Medical
Languages : en
Pages : 120

Book Description
In a workshop organized by the Clinical Research roundtable, representatives from purchaser organizations (employers), payer organizations (health plans and insurance companies), and other stakeholder organizations (voluntary health associations, clinical researchers, research organizations, and the technology community) came together to explore: What do purchasers and payers need from the Clinical Research Enterprise? How have current efforts in clinical research met their needs? What are purchasers, payers, and other stakeholders willing to contribute to the enterprise? This book documents these discussions and summarizes what employers and insurers need from and are willing to contribute to clinical research from both a business and a national health care perspective.

Virtual Clinical Trials

Virtual Clinical Trials PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309494885
Category : Medical
Languages : en
Pages : 127

Book Description
Successful drug development relies on accurate and efficient clinical trials to deliver the best and most effective pharmaceuticals and clinical care to patients. However, the current model for clinical trials is outdated, inefficient and costly. Clinical trials are limited by small sample sizes that do not reflect variations among patients in the real world, financial burdens on participants, and slow processes, and these factors contribute to the disconnect between clinical research and clinical practice. On November 28-29, the National Academies of Sciences, Engineering, and Medicine convened a workshop to investigate the current clinical trials system and explore the potential benefits and challenges of implementing virtual clinical trials as an enhanced alternative for the future. This publication summarizes the presentations and discussions from the workshop.