Bacterial Vaccines

Bacterial Vaccines PDF Author: Fadil Bidmos
Publisher: Humana
ISBN: 9781071619025
Category : Science
Languages : en
Pages : 0

Book Description
The importance of vaccines to combat bacterial diseases cannot be overstated. Methods used in the development and testing of these vaccines are evolving rapidly as a direct consequence of the availability of advanced technologies. This volume will cover methods developed in the last decade, the usage of which are enabling the development of cheaper, cost-effective and structurally stable vaccines for global use. Chapters cover in silico analytical methods such as reverse vaccinology and machine learning; low-energy electron irradiation for the generation of inactivated bacterial vaccines; methods for assessment of OMV/GMMA quality and stability; and controlled human infection models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Bacterial Vaccines: Methods and Protocols is a valuable resource for novice and expert researchers interested in learning more about this important and constantly evolving field.

Bacterial Vaccines

Bacterial Vaccines PDF Author: René Germanier
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 464

Book Description
Bacterial Vaccines provides information dealing with vaccination of man against bacterial diseases. This book emphasizes the description, composition, production, and control of the vaccines, as well as vaccine benefits and drawbacks. Organized into 14 chapters, this book contains a description of the etiological agent, particularly with respect to its antigenic composition, and also of the pathogenesis of the disease and the immune mechanisms acting against it. The chapters are separated according to the disease they describe, which include diphtheria, tetanus, pertussis, cholera, typhoid fev ...

New Bacterial Vaccines

New Bacterial Vaccines PDF Author: Ronald W. Ellis
Publisher: Springer Science & Business Media
ISBN: 1461500532
Category : Medical
Languages : en
Pages : 379

Book Description
New Bacterial Vaccines focuses upon unfulfilled needs for bacterial vaccines. The increase in drug resistance among many bacterial species has increased the need for new bacterial vaccines. This book serves as a comprehensive reference on the major aspects of developing new bacterial vaccines. The distinctive feature of this book is that it focuses upon new vaccines now under development by reviewing key issues for each vaccine target and new technologies being applied to developing new vaccines. This book should prove useful for students in the life sciences, scientists, developers of vaccines and biotechnology products, clinicians, regulators, and health-care practitioners.

CDC Yellow Book 2018: Health Information for International Travel

CDC Yellow Book 2018: Health Information for International Travel PDF Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
ISBN: 0190628634
Category : Medical
Languages : en
Pages : 705

Book Description
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Adverse Effects of Vaccines

Adverse Effects of Vaccines PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309214351
Category : Medical
Languages : en
Pages : 894

Book Description
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

Vaccine Analysis: Strategies, Principles, and Control

Vaccine Analysis: Strategies, Principles, and Control PDF Author: Brian K. Nunnally
Publisher: Springer
ISBN: 3662450240
Category : Medical
Languages : en
Pages : 669

Book Description
This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.

Vaccine Safety Forum

Vaccine Safety Forum PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309057914
Category : Medical
Languages : en
Pages : 71

Book Description
On November 6, 1995, the Institute of Medicine's Vaccine Safety Forum convened a workshop on detecting and responding to adverse events following vaccination. Workshop speakers and participants discussed the difficulties in detecting adverse events, current adverse events detection and response methods and procedures, suggestions for improving the means of detecting and responding to adverse events following vaccination, and future areas of research. This document represents a summary of that workshop.

Red Book

Red Book PDF Author: Larry K. Pickering
Publisher:
ISBN: 9781581107036
Category : Medical
Languages : en
Pages : 0

Book Description
Developed by the AAP (American Academy of Pediatrics) Committee on Infectious Diseases in conjunction with the CDC (Centers for disease control), the FDA (Food and drug administration), and other leading institutions with contributions from hundreds of physicians nationwide, the newly revised and updated 2012 Red Book continues the tradition of excellence with the latest findings and clinical recommendations on the manifestations, etiology, epidemiology, diagnosis, and treatment of more than 200 childhood conditions. [Ed.].

Bacterial Vaccines

Bacterial Vaccines PDF Author: Rene Germanier
Publisher: Academic Press
ISBN: 0323140211
Category : Medical
Languages : en
Pages : 456

Book Description
Bacterial Vaccines provides information dealing with vaccination of man against bacterial diseases. This book emphasizes the description, composition, production, and control of the vaccines, as well as vaccine benefits and drawbacks. Organized into 14 chapters, this book contains a description of the etiological agent, particularly with respect to its antigenic composition, and also of the pathogenesis of the disease and the immune mechanisms acting against it. The chapters are separated according to the disease they describe, which include diphtheria, tetanus, pertussis, cholera, typhoid fever, shigellosis, Escherichia coli infections, meningococcal meningitis, pneumococcal infections, Haemophilus influenzae type b infections, Pseudomonas aeruginosa infections, gonorrhea, tuberculosis, and leprosy. This book will provide the reader with a comprehensive survey of vaccination of man against bacterial diseases. It is intended for those involved in vaccine development, production, and control.

Disease Control Priorities, Third Edition (Volume 2)

Disease Control Priorities, Third Edition (Volume 2) PDF Author: Robert Black
Publisher: World Bank Publications
ISBN: 1464803684
Category : Medical
Languages : en
Pages : 419

Book Description
The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.