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Azoles

Azoles PDF Author: Aleksey Kuznetsov
Publisher: BoD – Books on Demand
ISBN: 1839681799
Category : Science
Languages : en
Pages : 148

Book Description
Azoles are a broad and promising class of five-membered heterocyclic compounds containing from one up to five nitrogen atom(s) that can also contain sulfur or oxygen atoms. Widely used as potent antifungal agents, various azole derivatives have also demonstrated many other promising biological properties. This book covers studies of several types of thiazole-based heterocyclic scaffolds, the development of 4-thiazolidinone and thiazole derivatives with heterocyclic fragments as potential candidates for new drugs against trypanosomiasis, numerous synthetic approaches for the synthesis of 1,2,3-triazoles, the application of N-azole, N,S-azole, and N,O-azole as well as their derivatives as retarders of metallic corrosion, and the integration of azoles in materials used for renewable energy processing and applications and wood treatment.

Azoles

Azoles PDF Author: Aleksey Kuznetsov
Publisher: BoD – Books on Demand
ISBN: 1839681799
Category : Science
Languages : en
Pages : 148

Book Description
Azoles are a broad and promising class of five-membered heterocyclic compounds containing from one up to five nitrogen atom(s) that can also contain sulfur or oxygen atoms. Widely used as potent antifungal agents, various azole derivatives have also demonstrated many other promising biological properties. This book covers studies of several types of thiazole-based heterocyclic scaffolds, the development of 4-thiazolidinone and thiazole derivatives with heterocyclic fragments as potential candidates for new drugs against trypanosomiasis, numerous synthetic approaches for the synthesis of 1,2,3-triazoles, the application of N-azole, N,S-azole, and N,O-azole as well as their derivatives as retarders of metallic corrosion, and the integration of azoles in materials used for renewable energy processing and applications and wood treatment.

Handbook of Antimicrobial Resistance

Handbook of Antimicrobial Resistance PDF Author: Matthias Gotte
Publisher: Springer
ISBN: 9781493906932
Category : Medical
Languages : en
Pages : 0

Book Description
While many volumes have been written about various aspects of antimicrobial resistance, this book is a comprehensive reference work. All manifestations of resistance are addressed: viral; bacterial, parasitical and fungal are given dedicated sections. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target), are highly diverse. This work discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.

Antifungal Therapy

Antifungal Therapy PDF Author: Mahmoud Ghannoum
Publisher: CRC Press
ISBN: 0849387868
Category : Medical
Languages : en
Pages : 484

Book Description
A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c

Heterocyclic Chemistry At A Glance

Heterocyclic Chemistry At A Glance PDF Author: John A. Joule
Publisher: John Wiley & Sons
ISBN: 1118380193
Category : Science
Languages : en
Pages : 332

Book Description
This expanded second edition provides a concise overview of the main principles and reactions of heterocyclic chemistry for undergraduate students studying chemistry and related courses. Using a successful and student-friendly "at a glance" approach, this book helps the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The chapters are thoroughly revised and updated with references to books and reviews; extra examples and student exercises with answers online; and color diagrams that emphasize exactly what is happening in the reaction chemistry depicted.

Nitroazoles: Synthesis, Structure and Applications

Nitroazoles: Synthesis, Structure and Applications PDF Author: Lyudmila Larina
Publisher: Springer Science & Business Media
ISBN: 0387980709
Category : Science
Languages : en
Pages : 454

Book Description
This volume is devoted to the synthesis, application, structure, and physicochemical properties of nitroazoles (five-membered aromatic compounds). The book is unique in providing the first comprehensive treatment of nitroazoles.

Applications of Heterocycles in the Design of Drugs and Agricultural Products

Applications of Heterocycles in the Design of Drugs and Agricultural Products PDF Author:
Publisher: Academic Press
ISBN: 0128201827
Category : Science
Languages : en
Pages : 332

Book Description
Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 in the Advances in Heterocyclic Chemistry series represents the most definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Chapters in this updated volume cover Hydroxy azoles as carboxylic acid bioisosteres, Cyclic sulfoxides and sulfones in drug design, Thiazoles and topological control in drug design, Applications of fused pyrrolidine [3.3.0] heterocycles in drug design, 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles in drug discovery and development: from the flask to the clinic, and Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines. Because biology and organic chemistry increasingly intersect, the associated nomenclature is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. - Considered the definitive serial in the field of heterocyclic chemistry - Serves as the go-to reference for organic chemists, polymer chemists and biological scientists - Provides the latest, comprehensive reviews written by established authorities in the field - Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Hepatotoxicity

Hepatotoxicity PDF Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 850

Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Clinical Mycology

Clinical Mycology PDF Author: William E. Dismukes
Publisher:
ISBN: 0195148096
Category : Medical
Languages : en
Pages : 534

Book Description
Within the field of infectious diseases, medical mycology has experienced significant growth over the last decade. Invasive fungal infections have been increasing in many patient populations, including: those with AIDS; transplant recipients; and the elderly. As these populations grow, so does the diversity of fungal pathogens. Paralleling this development, there have been recent launches of several new antifungal drugs and therapies. Clinical Mycology offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.

Clinical Small Animal Internal Medicine

Clinical Small Animal Internal Medicine PDF Author: David Bruyette
Publisher: John Wiley & Sons
ISBN: 1118497031
Category : Medical
Languages : en
Pages : 5143

Book Description
Clinical Small Animal Internal Medicine is a comprehensive, practical reference designed to meet the needs of veterinary practitioners and students alike. Covering all aspects of small animal internal medicine, this innovative guide provides clinically relevant material, plus podcasts and continual updates online. Concise, identically-formatted chapters allow readers to quickly find the most essential information for clinical veterinary practice. Contributions from academic and clinical experts cover general medicine subjects, including patient evaluation and management, critical care medicine, preventative care, and diagnostic and therapeutic considerations. Topics relevant to daily clinical practice are examined in detail, ranging from endocrine, cardiovascular, respiratory, and infectious disease to oncology, dermatology, metabolic orthopedic disease, gastroenterology, and hepatology. A companion website features podcasts and updated information. An important addition to the library of any practice, this clinically-oriented text: Presents complete, practical information on small animal internal medicine Provides the background physiology required to understand normal versus abnormal in real-world clinical settings Includes general medicine topics not covered in other internal medicine books Focuses on information that is directly applicable to daily practice Features podcasts and continual updates on a companion website Carefully tailored for the needs of small animal practitioners and veterinary students, Clinical Small Animal Internal Medicine is an invaluable, reader-friendly reference on internal medicine of the dog and cat.

Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts

Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts PDF Author:
Publisher:
ISBN: 9781562384692
Category : Antifungal agents
Languages : en
Pages : 30

Book Description