Author: Anne ReadingsPublisher:
ISBN:
Category :
Languages : en
Pages : 280
Book Description
Attitudes Towards Genetic Testing for Breast Cancer Susceptibility Risk
Author: Anne ReadingsWomen's Attitudes Toward Genetic Testing for Breast Cancer Susceptibility as a Function of Breast Cancer Screening Practices, Perceived Risk of Contracting Breast Cancer, Health Locus of Control and Genetic Knowledg
Author: Constance Faye WelebirPublisher:
ISBN:
Category : Breast
Languages : en
Pages : 306
Book Description
Genetic susceptibility testing for breast and ovarian cancer is an important new tool for assessing cancer risk, one that may facilitate early detection and reduction of cancer risk. Interest in testing among high risk women has been sizeable; however potetial demand for testing may be greatest among women for who testing is least appropriate.
Attitudes Towards Genetic Testing for Breast Cancer Susceptibility Among Breast Cancer Patients and Their Relatives
Author: Jennifer BeemanAssessing Genetic Risks
Author: Institute of MedicinePublisher: National Academies Press
ISBN: 0309047986
Category : Medical
Languages : en
Pages : 353
Book Description
Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Genetic Testing for Breast Cancer Susceptibility
Author: Grace-Ann Olayinka FasayePublisher:
ISBN:
Category :
Languages : en
Pages : 130
Book Description
Genetic Counseling for Breast Cancer Susceptibility in African American Women
Author: Publisher:
ISBN:
Category :
Languages : en
Pages : 52
Book Description
Increasingly, the cultural beliefs and values of women are being recognized as important factors in genetic counseling for breast cancer susceptibility. Despite recommendations to increase the cultural sensitivity of genetic counseling, such programs have not been developed or evaluated. The objectives of this study are to develop a Culturally Tailored Genetic (CTGC) protocol for African American women and evaluate its impact on decision-making and satisfaction about BRCA1/2 testing, quality of life, and cancer control practices. A secondary objective of this study is to identify African American women who are most and lest likely to benefit from CTGC vs. SGC. The key research accomplishments achieved during the past year include continuing subject recruitment, completing genetic counseling and education, and generating peer-reviewed manuscripts. The results generated during the past year demonstrate that it is possible to enroll African American women into genetic counseling research. Our findings also demonstrate that African American women at increased risk for hereditary breast cancer report positive attitudes about the benefits of genetic testing; however, these attitudes may not translate into high levels of interest in testing. CTGC may be one strategy for addressing beliefs about genetic testing and facilitating testing decisions among African American women.
Mammography and Beyond
Author: National Research CouncilPublisher: National Academies Press
ISBN: 0309171318
Category : Medical
Languages : en
Pages : 311
Book Description
Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.
In Control
Author: Neil F. SharpePublisher: Scarborough, Ont. : Prentice Hall Canada
ISBN:
Category : Health & Fitness
Languages : en
Pages : 252
Book Description
Hereditary Breast Cancer
Author: Claudine IsaacsPublisher: CRC Press
ISBN: 1420020366
Category : Medical
Languages : en
Pages : 402
Book Description
Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer. It offers clear guidance on the application and utilization of cancer risk assessment models, geneti
Risk Assessment, Genetic Counseling, and Genetic Testing for Brca-related Cancer
Author: U.S. Department of Health and Human ServicesPublisher: Createspace Independent Publishing Platform
ISBN: 9781495306136
Category : Medical
Languages : en
Pages : 368
Book Description
This systematic review is an update of the evidence for the U.S. Preventive Services Task Force (USPSTF) on the effectiveness and adverse effects of risk assessment, genetic counseling, and genetic testing for breast cancer susceptibility gene (BRCA)–related cancer in women who do not have cancer but are potentially at increased risk. Its purpose is to evaluate and summarize evidence addressing specific key questions important to the USPSTF as it considers new recommendations for primary care practice. In 2005, based on results of a previous review, the USPSTF recommended against routine referral for genetic counseling or routine BRCA testing for women whose family histories are not associated with increased risks for deleterious mutations in breast cancer susceptibility gene 1 (BRCA1) or breast cancer susceptibility gene 2 (BRCA2) (D recommendation). The USPSTF also recommended that women whose family histories are associated with increased risks for mutations in the BRCA1 or BRCA2 genes be referred for genetic counseling and evaluation for BRCA testing (B recommendation). The USPSTF concluded that the potential harms of routine referral for genetic counseling or BRCA mutation testing in women without family history risk outweigh the benefits, and that the benefits of referring women with family history risk to suitably trained health care providers outweigh the harms. Benefits included improved accuracy of risk assessment and pretest probability for testing and improved patient knowledge, risk perception, and psychological and health outcomes. Potential harms included inaccurate risk assessment; inappropriate testing; misinterpretation of test results; and ethical, legal, and social implications; among others. The 2005 USPSTF recommendation was intended for the primary prevention of cancer and applied to women without previous diagnoses of breast or ovarian cancer, consistent with the USPSTF scope of preventive care for the general population. Recommendations for men and women with cancer were not included. The 2005 USPSTF recommendation is included in the Affordable Care Act for covered preventive services, and provided the basis for a Healthy People 2020 objective to increase the proportion of women with family histories of breast or ovarian cancer who receive genetic counseling. The previous systematic review identified several research limitations and evidence gaps. The review concluded that a primary care approach to genetic risk assessment and BRCA mutation testing had not been evaluated, and evidence was lacking to determine the benefits and harms of this approach for women without cancer. Risk assessment, genetic counseling, and mutation testing did not cause adverse psychological outcomes, and counseling improved distress and risk perception in the highly-selected populations studied. Studies of intensive cancer screening approaches, such as earlier and more frequent mammography, were inconclusive. Trials of risk-reducing medications, such as tamoxifen and raloxifene, reported reduced breast cancer incidence in women with varying baseline levels of risk compared with placebo, but also increased adverse effects. Observational studies of risk-reducing mastectomy and salpingooophorectomy reported reduced breast and ovarian cancer outcomes in women who were mutation carriers.