Author: Oleg I. Kolodiazhnyi
Publisher: John Wiley & Sons
ISBN: 3527341536
Category : Science
Languages : en
Pages : 539
Book Description
Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Asymmetric Synthesis in Organophosphorus Chemistry
Author: Oleg I. Kolodiazhnyi
Publisher: John Wiley & Sons
ISBN: 3527341536
Category : Science
Languages : en
Pages : 539
Book Description
Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Publisher: John Wiley & Sons
ISBN: 3527341536
Category : Science
Languages : en
Pages : 539
Book Description
Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Asymmetric Synthesis of Organophosphorus Compounds
Author: Joseph J. Ruddy
Publisher:
ISBN:
Category : Organophosphorus compounds
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category : Organophosphorus compounds
Languages : en
Pages : 0
Book Description
Methodology Development for the Asymmetric Synthesis of Organophosphorus Compounds
Asymmetric Synthesis of Organophosphates and Their Derivatives
Author: Batool J. Murtadha
Publisher:
ISBN:
Category :
Languages : en
Pages : 106
Book Description
Organophosphorus compounds (OPs) are widely used in the agricultural industry especially in the pesticide market. Phosphates play a huge role as biological compounds in the form of energy carrier compounds like ATP, and medicine as antivirals. OPs have become increasingly important as evidenced by the publication of new methods devoted to their uses and synthesis. These well-established studies lay the basis for industrial organic derivatives of phosphorus preparations. The current work explored methods of synthesizing chiral organophosphate triesters. We experimented with different processes roughly divided into either an electrophilic or nucleophilic strategy using chiral Lewis acids, organocatalysts (HyperBTM), activating agents, and chiral auxiliaries with the goal of control stereoselectivity. These methods were explored through the use of different starting materials like POCl3, triethyl phosphate, methyl phosphordichloradate, and PSCl3. My research results suggest that most of the reactions only went to partial completion. Furthermore, most of the experiments were either non-effective product or the scientific data were not productive in the reaction, in fact, the product could not be isolated or purified. The synthesis reaction steps were evaluated through TLC, 1H NMR, and 31P NMR.
Publisher:
ISBN:
Category :
Languages : en
Pages : 106
Book Description
Organophosphorus compounds (OPs) are widely used in the agricultural industry especially in the pesticide market. Phosphates play a huge role as biological compounds in the form of energy carrier compounds like ATP, and medicine as antivirals. OPs have become increasingly important as evidenced by the publication of new methods devoted to their uses and synthesis. These well-established studies lay the basis for industrial organic derivatives of phosphorus preparations. The current work explored methods of synthesizing chiral organophosphate triesters. We experimented with different processes roughly divided into either an electrophilic or nucleophilic strategy using chiral Lewis acids, organocatalysts (HyperBTM), activating agents, and chiral auxiliaries with the goal of control stereoselectivity. These methods were explored through the use of different starting materials like POCl3, triethyl phosphate, methyl phosphordichloradate, and PSCl3. My research results suggest that most of the reactions only went to partial completion. Furthermore, most of the experiments were either non-effective product or the scientific data were not productive in the reaction, in fact, the product could not be isolated or purified. The synthesis reaction steps were evaluated through TLC, 1H NMR, and 31P NMR.
Metal-free Asymmetric Synthesis and Applications of Organosulfur and Organophosphorus Compounds
Phosphorus Chemistry I
Author: Jean-Luc Montchamp
Publisher: Springer
ISBN: 3319154737
Category : Science
Languages : en
Pages : 250
Book Description
Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Publisher: Springer
ISBN: 3319154737
Category : Science
Languages : en
Pages : 250
Book Description
Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Organophosphorus Chemistry
Author: György Keglevich
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110535831
Category : Science
Languages : en
Pages : 324
Book Description
Organophosphorus Chemistry presents a groundbreaking resource in this branch of organic chemistry that demonstrates how phosphorus-containing compounds can be manipulated in a variety of organic reactions. The authors give an overview of the newest trends and synthesis strategies, introduce bioactive and environmentally friendly organophosphorus compounds and show their importance in mainstream organic chemistry.
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110535831
Category : Science
Languages : en
Pages : 324
Book Description
Organophosphorus Chemistry presents a groundbreaking resource in this branch of organic chemistry that demonstrates how phosphorus-containing compounds can be manipulated in a variety of organic reactions. The authors give an overview of the newest trends and synthesis strategies, introduce bioactive and environmentally friendly organophosphorus compounds and show their importance in mainstream organic chemistry.
Asymmetric Synthesis in Organophosphorus Chemistry
Author: Oleg I. Kolodiazhnyi
Publisher: John Wiley & Sons
ISBN: 3527341501
Category : Science
Languages : en
Pages : 392
Book Description
Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Publisher: John Wiley & Sons
ISBN: 3527341501
Category : Science
Languages : en
Pages : 392
Book Description
Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Organophosphorus Chemistry: Volume 50
Author: John C. Tebby
Publisher: Royal Society of Chemistry
ISBN: 1839162058
Category : Science
Languages : en
Pages : 505
Book Description
This annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds.
Publisher: Royal Society of Chemistry
ISBN: 1839162058
Category : Science
Languages : en
Pages : 505
Book Description
This annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds.
Organophosphorus Chemistry
Author: David W Allen
Publisher: Royal Society of Chemistry
ISBN: 1788018648
Category : Science
Languages : en
Pages : 410
Book Description
This annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds, from phosphines and related P-C bonded compounds to phosphorus acids, phosphine chalcogenides and nucleotides. The Editors have added to the content with a timely chapter on the recent developments in green synthetic approaches in organophosphorus chemistry to reflect current interests in the area. With an emphasis on interdisciplinary content, this book is aimed at the worldwide organic chemistry and engineering research communities.
Publisher: Royal Society of Chemistry
ISBN: 1788018648
Category : Science
Languages : en
Pages : 410
Book Description
This annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds, from phosphines and related P-C bonded compounds to phosphorus acids, phosphine chalcogenides and nucleotides. The Editors have added to the content with a timely chapter on the recent developments in green synthetic approaches in organophosphorus chemistry to reflect current interests in the area. With an emphasis on interdisciplinary content, this book is aimed at the worldwide organic chemistry and engineering research communities.