Association Between Sleep Quality and Aging PDF Download

Author: Joel Ramirez
Publisher: Frontiers Media SA
ISBN: 2832545971
Category : Science
Languages : en
Pages : 133

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Book Description
With life expectancy on the rise, the proportion of people aged 60 or older is projected to account for more than one-fifth of the global population by 2050. Sleep quality is one of the most common health concerns that increases with age. Changes in sleep patterns associated with old age include disturbed sleep onset, an increase in sleep fragmentation, more frequent daytime dysfunction, and less slow-wave sleep than younger adults. Sleep is a complex physiological process critical to our health and survival; the many functions of sleep range from cerebral metabolic waste clearance and energy conservation to supporting cognitive performance and psychological well-being. Insufficient sleep has been linked to an increased risk of developing several chronic conditions, including type 2 diabetes, cardiovascular disease, immunodeficiency, chronic pain, depression, and neurodegenerative diseases such as dementia due to Alzheimer’s disease. What remains unclear is how variations in sleep quality are related to cognitive performance and how this relationship changes with age, with several decades of research on the subject having produced mixed results. Despite this, much recent evidence indicates a strong relationship between disturbed sleep and accelerated cognitive decline in older adults. For example, several studies have found that a loss in sleep quality precedes the emergence of cognitive deficits and that sleep disturbances may therefore constitute an early marker of cognitive decline. Sleep disturbances also become more extensive with the progression of neurodegenerative diseases, which raises questions about the possibility of a bidirectional relationship.

Author: Joris C. Verster
Publisher: Springer Science & Business Media
ISBN: 1603273433
Category : Medical
Languages : en
Pages : 517

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Book Description
Many patients experience sleep disturbances secondary to their primary illness and this often has a negative effect on their quality of life. This book provides an evidence-based introduction to the interface between sleep wide range of medical disorders. A clinically focused, comprehensive review for physicians and other health providers, this state-of-the-art reference can also serve as a textbook for those who wish to become familiar with the impact of sleep on quality of life.

Author: Susan Redline
Publisher: Springer Science & Business Media
ISBN: 146149527X
Category : Medical
Languages : en
Pages : 248

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Book Description
Sleep has recently been recognized as a critical determinant of energy balance regulating, restoration and repair of many of the physiologic and psychologic processes involved in modulating energy intake and utilization. In addition to having an impact on obesity, sleep abnormalities, both quantitative and qualitative, have now been shown to have significant effects on obesity associated comorbidities, including metabolic syndrome, premalignant lesions and cancer. Sleep problems and fatigue also constitute a significant challenge for the ever expanding group of cancer survivors. Moreover, circadian misalignment, such as that experienced by "shift workers" has been shown to be associated with an increased incidence of several malignancies including, breast, colorectal and prostate cancer, consistent with the increasing recognition of the role of clock genes in the metabolic processes. Of increasing concern is the accelerating incidence of sleep disorders in childhood, their association with childhood obesity and associated abnormalities of circulating cytokines, adipokines and metabolic factors, many of which are implicated as etiologic mediators of the connection between obesity and cancer. Extensive studies have now been initiated to investigate the mechanisms by which disturbances in sleep duration, sleep continuity and sleep related breathing affect circadian rhythm, central and peripheral tissue oxygenation and metabolism, quality and quantity of dietary intake and circulating inflammatory cytokines and regulatory hormones. This volume aims to present the latest research on sleep, sleep disturbance and its correlation to obesity and cancer.

Author: Roberto Cabeza
Publisher: Oxford University Press
ISBN: 0199728364
Category : Psychology
Languages : en
Pages : 425

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Book Description
Until very recently, our knowledge about the neural basis of cognitive aging was based on two disciplines that had very little contact with each other. Whereas the neuroscience of aging investigated the effects of aging on the brain independently of age-related changes in cognition, the cognitive psychology of aging investigated the effects of aging on cognition independently of age-related changes in the brain. The lack of communication between these two disciplines is currently being addressed by an increasing number of studies that focus on the relationships between cognitive aging and cerebral aging. This rapidly growing body of research has come to constitute a new discipline, which may be called cognitive neuroscience of aging. The goal of Cognitive Neuroscience of Aging is to introduce the reader to this new discipline at a level that is useful to both professionals and students in the domains of cognitive neuroscience, cognitive psychology, neuroscience, neuropsychology, neurology, and other, related areas. This book is divided into four main sections. The first section describes noninvasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical (e.g., dopamine PET), electrophysiological (e.g., ERPs), and hemodynamic (e.g., fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging on neural activity during different cognitive functions, including perception and attention, imagery, working memory, long-term memory, and prospective memory. The third section focuses on clinical and applied topics, such as the distinction between healthy aging and Alzheimers disease and the use of cognitive training to ameliorate age-related cognitive decline. The last section describes theories that relate cognitive and cerebral aging, including models accounting for functional neuroimaging evidence and models supported by computer simulations. Taken together, the chapters in this volume provide the first unified and comprehensive overview of the new discipline of cognitive neuroscience of aging.

Author: Mark P. Mattson
Publisher: Elsevier
ISBN: 9780444518767
Category : Medical
Languages : en
Pages : 212

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Book Description
Sleep and Aging provides a unique and timely collection of review articles that cover the gamut of basic and clinical aspects of sleep and the abnormalities in sleep associated with aging and neurological disorders that occur during aging. From the evolutionary basis of sleep and its normal functions in processes such as learning and memory, to considerations of the roles of sleep abnormalities in neurological disorders such as depression, Alzheimer's and Parkinson's diseases, the chapters are written by experts in the field. Several chapters focus on signalling pathways involved in sleep regulation and abnormalities in sleep, including those activated by serotonin and BDNF. Basic and clinical research on insomnia, sleep apnea and other disorders of sleep, are covered thus providing students and scientists at all levels with a valuable source of information to advance their understanding of this important topic in aging, biology and medicine. The circuits in the brain involved in sleep regulation, their neurochemistry, how they are altered in disorders of sleep and current clinical treatments of various sleep disorders are reviewed. The important role of sleep disturbances in neurodegenerative disorders is described and research in this particular area is leading to a better understanding of the relationships between synaptic plasticity, neuronal degeneration and the clinical manifestations of disorders such as Alzheimer's disease, Parkinson's disease and depression. This book is a must for scientists, as well as non-scientists, who are interested in the neurobiology of aging, sleep and neurodegenerative disorders.

Author: Carl Salzman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781743808
Category : Medical
Languages : en
Pages : 728

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Book Description
Thoroughly updated for its Fourth Edition, this volume is the most authoritative clinical reference on the pharmacologic treatment of psychiatric disorders in elderly patients. This edition provides complete information on new psychotropic drugs, new uses for established drugs, and clinically relevant advances in the neurosciences. Four new chapters cover genes, pharmacokinetics, and their impact on prescribing; new cognitive-enhancing strategies and drugs; late-life depression and physical illness; and depression and cardiac disease in late life. The book offers detailed guidelines—including drug names, dosages, and prescribing recommendations—for pharmacologic treatment of specific disorders. Chapters include clinical vignettes and tables presenting current clinical trial data. Appendices provide succinct information on prescribing and drug interactions.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309101115
Category : Medical
Languages : en
Pages : 425

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Book Description
Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

Author: Helen Lavretsky
Publisher: Oxford University Press
ISBN: 0199796815
Category : Medical
Languages : en
Pages : 795

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Book Description
Late-life Mood Disorders provides a comprehensive review of the current research advances in neurobiology and psychosocial origins of geriatric mood disorders. The review of the latest developments and "gold standards" of care is provided by an international group of leading experts.

Author: Miranda A. Farage
Publisher: Springer Science & Business Media
ISBN: 3540896554
Category : Medical
Languages : en
Pages : 1255

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Book Description
This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.

Author: Gregory R. Pierce
Publisher: Springer Science & Business Media
ISBN: 9780306455353
Category : Medical
Languages : en
Pages : 526

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Book Description
The Sourcebook gives special attention to the complexity of the social support construct, expanding the field's theoretical base by reappraising social support research in the context of findings from other fields of psychology & related disciplines.