Assessing the Pharmacological Effects and Therapeutic Potential of Traditional Chinese Medicine in Neurological Disease Models: An Update PDF Download

Author: Jiahong Lu
Publisher: Frontiers Media SA
ISBN: 2889761916
Category : Science
Languages : en
Pages : 289

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Book Description

Author: Colin R Martin
Publisher: Elsevier
ISBN: 032388444X
Category : Medical
Languages : en
Pages : 1070

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Book Description
Treatments, Nutraceuticals, Supplements and Herbal Medicine in Neurological Disorders offers readers a comprehensive reference on their potential for treatment in a wide variety of neurological diseases. Spanning various types of these compounds, this broad coverage allows readers to learn about the use of nutraceuticals and botanicals alone, or in combination with, other dietary regimes and/or vitamins and minerals. It covers diseases including Alzheimer's, Parkinson's, ALS and MS, and severe neurological conditions including brain injury, stroke, headache and migraine. This volume provides a platform for research on nutraceuticals and botanical agents and on future investigations of these compounds. There are over 600 neurological disorders affecting both the central and peripheral nervous systems, some of which have been treated by nutraceuticals and herbal medicine, hence this is a timely resource on the topics covered. - Summarizes nutraceutical and herbal medicine research for a variety of neurological conditions - Contains chapter abstracts, key facts, a dictionary and a summary - Covers nutraceutical and botanical use in Alzheimer's, Parkinson's, ALS, MS, and more - Includes conditions like migraine, headache, stroke and brain injury

Author: Shao Li
Publisher: Frontiers Media SA
ISBN: 2832507026
Category : Science
Languages : en
Pages : 664

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Author: María Gómez-Cañas
Publisher: Frontiers Media SA
ISBN: 2832512690
Category : Science
Languages : en
Pages : 199

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Book Description

Author: Liming Lu
Publisher: Frontiers Media SA
ISBN: 2832521746
Category : Medical
Languages : en
Pages : 333

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Book Description
Neurological disorders, such as Alzheimer's disease and Parkinson's disease, are an important cause of disability and death worldwide and pose a serious burden on the global health system over the past 30 years. Acupuncture, as the most widely used traditional Chinese medicine therapy in the world, has been widely used in 183 countries and regions. Acupuncture can treat more than 300 kinds of diseases, especially for neurological diseases. Due to the unique advantages of acupuncture such as good therapeutic effect and low side effects, many researchers have conducted extensive clinical studies on the effectiveness and safety of acupuncture in the treatment of neurological diseases, laying a foundation for the practicability and scientific vigor of this complementary and alternative therapeutic approach. There are still many problems unanswered in the current clinical research on acupuncture for the treatment of neurological diseases: First of all, clinical research is lagging behind due to the lack of emphasis on modern advanced methods and analytical techniques (e.g., artificial intelligence, omics analysis, bioinformatics analysis, data mining) and multidisciplinary integration process. Secondly, the quality of reports on most clinical studies of acupuncture treatment for neurological diseases is extremely low. Most clinical studies have not adopted standardized methodological evaluations, authoritative disease diagnosis standards, and efficacy evaluation standards. The lack of compliance regulations and strict study design reduces the accuracy and authenticity of the research. Thirdly, there is a lack of integrated assessment of the distribution of evidence for acupuncture treatment of neurological diseases. Therefore, strictly designed clinical research and in depth and systematic analysis method are currently needed to provide high-quality evidence for acupuncture treatment of neurological diseases. In this Research Topic, we hope to further understand the role of acupuncture in the treatment of neurological diseases through clinical research and secondary research. The range of acupuncture includes manual acupuncture, electro-acupuncture, body needling, auricular acupuncture, scalp acupuncture, laser acupuncture and acupressure, etc. Neurological diseases include stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson's disease, epilepsy, multiple sclerosis, motor neurone disease, migraine, tense-type headaches, headaches from drug overuse, and others.

Author: Rui Liu
Publisher: Frontiers Media SA
ISBN: 2832505635
Category : Science
Languages : en
Pages : 282

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Author: Jianxun Liu
Publisher: Frontiers Media SA
ISBN: 2889717984
Category : Science
Languages : en
Pages : 227

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Book Description
Cardiovascular diseases include ischemic and hemorrhagic diseases involving the heart, brain, whole body tissue, and includes coronary heart disease, heart failure, arrhythmia, atherosclerosis and stroke. This particular group of diseases continue to be a leading cause of death throughout the world with mortality rate remaining high. Currently, drugs administered orally and intravenously and surgical treatments are used to treat such diseases. Traditional Chinese medicine (TCM) refers to natural herbal medicines and their processed products used for preventing and treating disease under the guidance of traditional Chinese medicine’s theory. The implementation of prevention and treatment programs of ischemic cardiovascular diseases with the use of TCM have been associated with positive outcomes; in terms of a reduction in the disability and mortality rate of some patients. Other studies have also shown that specific multi-component TCM preparations have therapeutic benefits based on multi-target and multi-pathway mechanisms, which may have advantages over the current single-component and single-target therapy. Based these characteristics, approved pharmaceutical drugs based in TCM, such as Compound Danshen Dripping Pills, Naoxintong Capsules, Tonxinluo Capsules, and Danhong Injection, are currently used to treat cardiovascular diseases. However, there are a number of areas that still need further investigation. For example, the identification of effective components in herbal medicine is essential in furthering our understanding of what occurs at a pharmacological level; the metabolizing pharmacological pathways of such components; the cellular target of the components; and the lack of standardized guidelines to enhance clinical research.

Author: Jaime Ribeiro-Filho
Publisher: Frontiers Media SA
ISBN: 2832500617
Category : Science
Languages : en
Pages : 253

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Author: Stalin Antony
Publisher: Frontiers Media SA
ISBN: 2832553435
Category : Science
Languages : en
Pages : 181

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Book Description
Metabolic diseases such as type 2 diabetes mellitus (T2DM), obesity, non-alcoholic fatty liver disease (NAFLD), and cancer are among the most prevalent health problems worldwide. These diseases are characterized by altered metabolism and impaired energy homeostasis, leading to the development of chronic diseases. Medicines derived from plants and fungi including herbal extracts and isolated compounds, have been used for centuries to treat various ailments and have recently gained renewed attention as potential therapeutics for metabolic diseases. Pharmacological approaches are essential for developing such preparations to treat these diseases. Computational approaches can generate early-stage hypotheses about potential targets and mechanisms and can be one basis for assessing the pharmacological activity of an extract or a metabolite. Understanding the molecular mechanisms underlying metabolic diseases and the potential benefits of herbal medicines (incl. herbal medical products) can provide valuable insights into new therapeutic targets and treatment options.

Author: Ochuko Lucky Erukainure
Publisher: Frontiers Media SA
ISBN: 2832545564
Category : Science
Languages : en
Pages : 237

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Book Description
Oxidative and metabolic diseases represent a large proportion of global challenges to health and quality of life. These diseases are often characterised by the imbalance between the cellular prooxidant (products of metabolic processes) and the antioxidant molecules within the cells. The imbalance often led to the underlying factors that exacerbate the pathogenesis of some life-threatening diseases such as carcinogenesis, obesity, diabetes, and cardiovascular diseases. Natural products, including phytochemicals and functional foods are known for their ability to affect metabolic processes such as ameliorating reactive oxygen species-induced mitochondria dysfunction, mitigating inflammatory response, and other cellular functions that could ameliorate the disease developments. Despite the relatively low toxicities of natural products as compared with synthetic products, further studies are still required to optimize the bioavailability, therapeutics, pharmaceutics, and clinical trials of natural products in patients suffering oxidative and metabolic diseases.