Aspects Of Crystallography In Molecular Biology PDF Download

Author: S. Parthasarathy
Publisher:
ISBN: 9788122410839
Category : Crystals
Languages : en
Pages : 410

View

Book Description

Author: Dino Moras
Publisher: Springer Science & Business Media
ISBN: 146845272X
Category : Science
Languages : en
Pages : 424

View

Book Description

Author: Alexander Wlodawer
Publisher: Humana Press
ISBN: 9781493969982
Category : Science
Languages : en
Pages : 672

View

Book Description
This volume provides methods for modern macromolecular crystallography, including all steps leading to crystal structure determination and analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protein Crystallography aims to ensure successful results in the further study of this vital field.

Author: Duncan E. McRee
Publisher: Academic Press
ISBN: 0323138888
Category : Science
Languages : en
Pages : 403

View

Book Description
Designed for easy use by both new and experienced protein crystallographers, this much-needed book is for anyone interested in solving protein structures by the method of crystallography. It contains many examples ofactual experiments and data, including electron density maps. Computer methods and computer code samples are presented. Practical Protein Crystallography is loaded with new information on area detectors, synchrotron radiation techniques, and the latest computer methods, and features the XtalView software system. Graduate students and teachers in physical biochemistry and pharmaceutical researchers will find this text a timely and convenient aid.

Author: T. L. Blundell
Publisher: Academic Press
ISBN:
Category : Science
Languages : en
Pages : 592

View

Book Description

Author: Maria Armenia Carrondo
Publisher: Springer Science & Business Media
ISBN: 9400725299
Category : Science
Languages : en
Pages : 213

View

Book Description
This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.

Author: Dennis Sherwood
Publisher: Oxford University Press
ISBN: 019955904X
Category : Language Arts & Disciplines
Languages : en
Pages : 640

View

Book Description
Information derived from X-ray crystal structures of biological molecules allows us to explain their functions in living organisms in extraordinary detail, and to develop drugs to treat disease. This book describes the principles and practice of X-ray diffraction as a key technique at the forefront of new discoveries in biology and medicine.

Author: Gwyndaf Evans
Publisher: Royal Society of Chemistry
ISBN: 1782627286
Category : Science
Languages : en
Pages : 244

View

Book Description
Protein crystallography has become vital to further understanding the structure and function of many complex biological systems. In recent years, structure determination has progressed tremendously however the quality of crystals and data sets can prevent the best results from being obtained. With contributions from world leading researchers whose software are used worldwide, this book provides a coherent approach on how to handle difficult crystallographic data and how to assess its quality. The chapters will cover all key aspects of protein crystallography, from instrumentation and data processing through to model building. This book also addresses challenges that protein crystallographers will face such as dealing with data from microcrystals and multi protein complexes. This book is ideal for both academics and researchers in industry looking for a comprehensive guide to protein crystallography.

Author: Kevin J. Roberts
Publisher: Springer
ISBN: 9402411178
Category : Science
Languages : en
Pages : 481

View

Book Description
This book highlights the current state-of-the-art regarding the application of applied crystallographic methodologies for understanding, predicting and controlling the transformation from the molecular to crystalline state with the latter exhibiting pre-defined properties. This philosophy is built around the fundamental principles underpinning the three inter-connected themes of Form (what), Formation (how) and Function (why). Topics covered include: molecular and crystal structure, chirality and ferromagnetism, supramolecular assembly, defects and reactivity, morphology and surface energetics. Approaches for preparing crystals and nano-crystals with novel physical, chemical and mechanical properties include: crystallisation, seeding, phase diagrams, polymorphic control, chiral separation, ultrasonic techniques and mechano-chemistry. The vision is realised through examination of a range of advanced analytical characterisation techniques including in-situ studies. The work is underpinned through an unprecedented structural perspective of molecular features, solid-state packing arrangements and surface energetics as well as in-situ studies. This work will be of interest to researchers, industrialists, intellectual property specialists and policy makers interested in the latest developments in the design and supply of advanced high added-value organic solid-form materials and product composites.

Author: Anthony Michael Glazer
Publisher: Oxford University Press
ISBN: 0198717598
Category : Science
Languages : en
Pages : 169

View

Book Description
A long history -- Symmetry -- Crystal structures -- Diffraction -- Seeing atoms -- Sources of radiation