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Author: Yangyang Yang Publisher: Springer ISBN: 4431557695 Category : Science Languages : en Pages : 82
Book Description
In this book, the author deals mainly with two topics: (1) single-molecule visualization of switching behaviors in the DNA nanoframe system utilizing different kinds of molecular switches through the use of high-speed atomic force microscope (AFM); (2) construction of photocontrollable DNA nanostructures in programmed patterns and direct visualization of the dynamic assembling process. Here, high-speed AFM was employed to observe the dynamic movements of single molecules. Compared to a traditional single-molecule analysis method, such as fluorescence spectroscopy or electron microscopy, high-speed AFM makes possible the real-time observation of molecule behaviors. DNA nanostructures were designed and assembled as scaffolds to incorporate interested biomolecules. The observations were carried out under robust conditions without complicated pretreatment. Moreover, the photoresponsive molecules were successfully assembled into around 100 nm-sized DNA nanostructures. The assembly/disassembly of nanostructures can be regulated reversibly by photoirradiation. This book explains how DNA origami has gradually become a useful tool for the investigation of biochemical interactions in defined nanospace. It also shows the possibility of DNA nanostructures acting as nanodevices for application in biological systems, serving as a good introduction to basic DNA nanotechnology.
Author: Yangyang Yang Publisher: Springer ISBN: 4431557695 Category : Science Languages : en Pages : 82
Book Description
In this book, the author deals mainly with two topics: (1) single-molecule visualization of switching behaviors in the DNA nanoframe system utilizing different kinds of molecular switches through the use of high-speed atomic force microscope (AFM); (2) construction of photocontrollable DNA nanostructures in programmed patterns and direct visualization of the dynamic assembling process. Here, high-speed AFM was employed to observe the dynamic movements of single molecules. Compared to a traditional single-molecule analysis method, such as fluorescence spectroscopy or electron microscopy, high-speed AFM makes possible the real-time observation of molecule behaviors. DNA nanostructures were designed and assembled as scaffolds to incorporate interested biomolecules. The observations were carried out under robust conditions without complicated pretreatment. Moreover, the photoresponsive molecules were successfully assembled into around 100 nm-sized DNA nanostructures. The assembly/disassembly of nanostructures can be regulated reversibly by photoirradiation. This book explains how DNA origami has gradually become a useful tool for the investigation of biochemical interactions in defined nanospace. It also shows the possibility of DNA nanostructures acting as nanodevices for application in biological systems, serving as a good introduction to basic DNA nanotechnology.
Author: Kehao Huang Publisher: ISBN: Category : DNA nanotechnology Languages : en Pages : 0
Book Description
As the rising of structural DNA nanotechnology, scaffolded DNA origami emerged earlier this century. Development and application of this new technology has been surging due to its programmable and self-assembling ability. For multilayer 3-dimensional DNA origami nanostructures, there are three basic routes of development, which are dynamic structures, higher-order assemblies, and DNA origami-nanoparticle composites. Different routes of development can be combined to form nanostructures and nanodevices with significant complexity. This study has focused on the route of higher-order assembly of a dynamic structure, and nanoparticles were attached to the higher-order structure after they are formed. In detail, since hinge mechanism is one of the basic dynamic mechanisms for any mechanical device, a pre-designed DNA origami hinge structure was used as the dynamic structure of focus. One unit of the hinge structure was seen as a monomer. Using single-stranded DNA strands on the surface of the hinge structure and the unique base pairing nature of DNA, a controlled sideways polymerization of the hinge structure with a degree of 3 was performed and optimized. The product of polymerization with a degree of 3 is a trimer. Gold nanoparticles (AuNPs) were then attached to the interior of the hinge trimer to form the desired high-complexity nanostructure which has a wide variety of potential applications in the future.
Author: Masayuki Endo Publisher: John Wiley & Sons ISBN: 1119682584 Category : Technology & Engineering Languages : en Pages : 436
Book Description
DNA ORIGAMI Discover the impact and multidisciplinary applications of this subfield of DNA nanotechnology DNA origami refers to the technique of assembling single-stranded DNA template molecules into target two- and three-dimensional shapes at the nanoscale. This is accomplished by annealing templates with hundreds of DNA strands and then binding them through the specific base-pairing of complementary bases. The inherent properties of these DNA molecules—molecular recognition, self-assembly, programmability, and structural predictability—has given rise to intriguing applications from drug delivery systems to uses in circuitry in plasmonic devices. The first book to examine this important subfield, DNA Origami brings together leading experts from all fields to explain the current state and future directions of this cutting-edge avenue of study. The book begins by providing a detailed examination of structural design and assembly systems and their applications. As DNA origami technology is growing in popularity in the disciplines of chemistry, materials science, physics, biophysics, biology, and medicine, interdisciplinary studies are classified and discussed in detail. In particular, the book focuses on DNA origami used for creating new functional materials (combining chemistry and materials science; DNA origami for single-molecule analysis and measurements (as applied in physics and biophysics); and DNA origami for biological detection, diagnosis and therapeutics (medical and biological applications). DNA Origami readers will also find: A complete guide for newcomers that brings together fundamental and developmental aspects of DNA origami technology Contributions by a leading team of experts that bring expert views from different angles of the structural developments and applications of DNA origami An emerging and impactful research topic that will be of interest in numerous multidisciplinary areas A helpful list of references provided at the end of each chapter to give avenues for further study Given the wide scope found in this groundbreaking work, DNA Origami is a perfect resource for nanotechnologists, biologists, biophysicists, chemists, materials scientists, medical scientists, and pharmaceutical researchers.
Author: Joshua A. Johnson Publisher: ISBN: Category : Biophysics Languages : en Pages :
Book Description
Control, and the degree thereof, is a critical factor to characterize for utilizing any technology. As the field of nanotechnology has progressed, the wonderful potential of technologies on the molecular scale have been held back by the difficulty in controlling the precise arrangement and interactions between molecules to create objects with desired properties and functions. The rise of DNA nanotechnology has provided a path to fully realize the potential of nanotechnology through the programmable self-assembly of DNA strands into complex geometries. Specifically, the more recently developed technology known as DNA origami offers a means to create nanoscale structures or mechanisms with nearly any imaginable geometry and with sub-nanometer precision. This thesis focuses on exploring methods for controlling DNA origami on multiple scales. Initially, this thesis will discuss methods for controlling the self-assembly of DNA origami, which can be used to form multiple nanostructures simultaneously from a complex mixture. The relative strengths of self-assembly reactions help illuminate how such processes can be so efficient in simpler contexts. We show that, not only is it possible to fold multiple nanostructures in a single pot but also that the relative yields of each structure can be tuned. We find that the kinetics of folding for small regions of a structure is a dominant factor in these yields.
Author: Jaber, Wassim Publisher: IGI Global ISBN: Category : Technology & Engineering Languages : en Pages : 313
Book Description
In the world of academia, scholars and researchers are confronted with a rapidly expanding knowledge base in Artificial Intelligence (AI) and nanotechnology. The integration of these two groundbreaking fields presents an intricate web of concepts, innovations, and interdisciplinary applications that can overwhelm even the most astute academic minds. Staying up to date with the latest developments and effectively navigating this complex terrain has become a pressing challenge for those striving to contribute meaningfully to these fields. Artificial Intelligence in the Age of Nanotechnology is a transformative solution meticulously crafted to address the academic community's knowledge gaps and challenges. This comprehensive book serves as the guiding light for scholars, researchers, and students grappling with the dynamic synergy between AI and Nanotechnology. It offers a structured and authoritative exploration of the core principles and transformative applications of these domains across diverse fields. By providing clarity and depth, it empowers academics to stay at the forefront of innovation and make informed contributions.
Author: Publisher: Academic Press ISBN: 012812296X Category : Technology & Engineering Languages : en Pages : 1881
Book Description
Comprehensive Nanoscience and Technology, Second Edition, Five Volume Set allows researchers to navigate a very diverse, interdisciplinary and rapidly-changing field with up-to-date, comprehensive and authoritative coverage of every aspect of modern nanoscience and nanotechnology. Presents new chapters on the latest developments in the field Covers topics not discussed to this degree of detail in other works, such as biological devices and applications of nanotechnology Compiled and written by top international authorities in the field
Author: Eugen Stulz Publisher: John Wiley & Sons ISBN: 1118696867 Category : Technology & Engineering Languages : en Pages : 538
Book Description
This book covers the emerging topic of DNA nanotechnology and DNA supramolecular chemistry in its broader sense. By taking DNA out of its biological role, this biomolecule has become a very versatile building block in materials chemistry, supramolecular chemistry and bio-nanotechnology. Many novel structures have been realized in the past decade, which are now being used to create molecular machines, drug delivery systems, diagnosis platforms or potential electronic devices. The book combines many aspects of DNA nanotechnology, including formation of functional structures based on covalent and non-covalent systems, DNA origami, DNA based switches, DNA machines, and alternative structures and templates. This broad coverage is very appealing since it combines both the synthesis of modified DNA as well as designer concepts to successfully plan and make DNA nanostructures. Contributing authors have provided first a general introduction for the non-specialist reader, followed by a more in-depth analysis and presentation of their topic. In this way the book is attractive and useful for both the non-specialist who would like to have an overview of the topic, as well as the specialist reader who requires more information and inspiration to foster their own research.
Author: Ashutosh Tiwari Publisher: John Wiley & Sons ISBN: 1118998898 Category : Technology & Engineering Languages : en Pages : 360
Book Description
The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications
Author: Kangshun Li Publisher: Springer ISBN: 9811316511 Category : Computers Languages : en Pages : 578
Book Description
This two-volume set (CCIS 873 and CCIS 874) constitutes the thoroughly refereed proceedings of the 9th International Symposium, ISICA 2017, held in Guangzhou, China, in November 2017. The 101 full papers presented in both volumes were carefully reviewed and selected from 181 submissions. This second volume is organized in topical sections on swarm intelligence: cooperative Search, swarm optimization; complex systems modeling: system dynamic, multimedia simulation; intelligent information systems: information retrieval, e-commerce platforms; artificial intelligence and robotics: query optimization, intelligent engineering; virtualization: motion-based tracking, image recognition.
Author: Yangyang Yang
Author: Yangyang Yang
Author: Nadrian C. Seeman
Author: Kehao Huang
Author: Masayuki Endo
Author: Joshua A. Johnson
Author: Jaber, Wassim
Author: 
Author: Eugen Stulz
Author: Ashutosh Tiwari
Author: Kangshun Li