Dissertation Abstracts International

Dissertation Abstracts International PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 868

Book Description


Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 424

Book Description
Theses on any subject submitted by the academic libraries in the UK and Ireland.

Stereoselective Synthesis of Drugs and Natural Products

Stereoselective Synthesis of Drugs and Natural Products PDF Author: Vasyl Andrushko
Publisher: John Wiley & Sons
ISBN: 1118628330
Category : Science
Languages : en
Pages : 1836

Book Description
Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Practical Medicinal Chemistry with Macrocycles

Practical Medicinal Chemistry with Macrocycles PDF Author: Eric Marsault
Publisher: John Wiley & Sons
ISBN: 1119092566
Category : Science
Languages : en
Pages : 617

Book Description
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations

Progress in Heterocyclic Chemistry

Progress in Heterocyclic Chemistry PDF Author: Gordon Gribble
Publisher: Elsevier
ISBN: 0080458564
Category : Science
Languages : en
Pages : 459

Book Description
This is the seventeenth annual volume of Progress in Heterocyclic Chemistry, which covers the literature published during 2004 on most of the important heterocyclic ring systems. The volume opens with two specialized reviews: Dennis Wright covers Furans as Versatile Synthons for Target-Oriented and Diversity-Oriented Synthesis; and John Hepworth and Mark Heron discuss 'The Synthesis and Photochromic Properties of Naphthopyrans'. The remaining chapters examine the recent literature on the common heterocycles in order of increasing ring size and the heteroatoms present. - Includes new contributions from experts in the field - Covers literature published during 2004 on most of the important heterocyclic ring systems - Presents reviews on Versatile Synthons for Target-Oriented and Diversity-Oriented Synthesis; and Synthesis and Photochromic Properties of Naphthopyrans

Index Medicus

Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2084

Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Organic Synthesis

Organic Synthesis PDF Author: Douglass F. Taber
Publisher: John Wiley & Sons
ISBN: 0470056304
Category : Science
Languages : en
Pages : 200

Book Description
The first in a new series, this book provides chemists an effective, much-needed way to stay abreast of recent developments in organic synthesis. The 103 articles review the leading synthetic procedures developed from 2003 - 2005, discussing their significance and their applications. More than 100 reactions are covered, including Heterocycle Construction by Grubbs Metathesis, Enantioselective C-C Bond Construction, and Organic Reactions in Ionic Liquids.

Total Synthesis of (±)-Maoecrystal V

Total Synthesis of (±)-Maoecrystal V PDF Author: Jianxian Gong
Publisher: Springer
ISBN: 3642543049
Category : Science
Languages : en
Pages : 146

Book Description
In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.

Organic Reactions, Volume 108

Organic Reactions, Volume 108 PDF Author:
Publisher: John Wiley & Sons
ISBN: 1119832071
Category : Science
Languages : en
Pages : 1026

Book Description
The 108th volume in this series for organic chemists in academia and industry presents critical discussions of the following widely used organic reactions: CYCLIZATION REACTIONS OF NITROGEN-CENTERED RADICALS Stuart W. McCombie, Béatrice Quiclet-Sire, and Samir Z. Zard TRANSITION-METAL-CATALYZED AMINOOXYGENATION OF ALKENES Sherry R. Chemler, Dake Chen, Shuklendu D. Karyakarte, Jonathan M. Shikora, and Tomasz Wdowik

Organic Azides

Organic Azides PDF Author: Stefan Bräse
Publisher: John Wiley & Sons
ISBN: 0470682523
Category : Science
Languages : en
Pages : 536

Book Description
Most current state-of-the-art overview of this important class of compounds, encompassing many new and emerging applications The number of articles on organic azides continues to increase tremendously; on average, there are more than 1000 new publications a year Covers basic chemistry as well as state-of-the-art applications in life science and materials science World-ranked authors describe their own research in the wider context of azide chemistry Includes a chapter on safe synthesis and handling (azides can decompose explosively)