Application of Hydrocyclone for Cell Separation in Mammalian Cell Perfusion Cultures PDF Download

Author: Elsayed Ahmed Elsayed Ahmed
Publisher: Cuvillier Verlag
ISBN: 3865376347
Category :
Languages : en
Pages : 155

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Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
ISBN: 3527335951
Category : Medical
Languages : en
Pages : 528

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Book Description
With contributions from biotechnologists and bioengineers, this ready reference describes the state of the art in industrial biopharmaceutical production, with a strong focus on continuous processes. Recent advances in single-use technology as well as application guidelines for all types of biopharmaceutical products, from vaccines to antibodies, and from bacterial to insect to mammalian cells are covered. The efficiency, robustness, and quality control of continuous production processes for biopharmaceuticals are reviewed and compared to traditional batch processes for a range of different production systems.

Author: Leda Castilho
Publisher: Taylor & Francis
ISBN: 113409972X
Category : Medical
Languages : en
Pages : 506

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Book Description
Animal Cell Technology: from Biopharmaceuticals to Gene Therapy provides a comprehensive insight into biological and engineering concepts related to mammalian and insect cell technology, as well as an overview of the applications of animal cell technology. Part 1 of the book covers the Fundamentals upon which this technology is based and covers the science underpinning the technology. Part 2 covers the Applications from the production of therapeutic proteins to gene therapy. The authors of the chapters are internationally-recognized in the field of animal cell culture research and have extensive experience in the areas covered in their respective chapters.

Author: E. Lindner-Olsson
Publisher: Springer Science & Business Media
ISBN: 9401003696
Category : Science
Languages : en
Pages : 657

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Book Description
Proceedings of the 17th ESACT Meeting June 10-14, 2001, Tylösand, Sweden

Author: Vishwas G. Pangarkar
Publisher: John Wiley & Sons
ISBN: 1118807561
Category : Technology & Engineering
Languages : en
Pages : 532

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Book Description
Details simple design methods for multiphase reactors in the chemical process industries Includes basic aspects of transport in multiphase reactors and the importance of relatively reliable and simple procedures for predicting mass transfer parameters Details of design and scale up aspects of several important types of multiphase reactors Examples illustrated through design methodologies presenting different reactors for reactions that are industrially important Includes simple spreadsheet packages rather than complex algorithms / programs or computational aid

Author: Allan Matte
Publisher: Elsevier
ISBN: 0128186577
Category : Medical
Languages : en
Pages : 224

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Book Description
Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book. - Covers the vital new area of R&D on therapeutic antibodies - Written by leading scientists and researchers - Up-to-date coverage and includes a detailed bibliography

Author: K. Schügerl
Publisher: Springer
ISBN: 3540457364
Category : Technology & Engineering
Languages : en
Pages : 286

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Book Description
This special volume "Tools and Applications of Biochemical Engineering Science" is dedicated to Professor Wolf-Dieter Deckwer on the occasion of his 60th bir- day. It was a great pleasure for me to act together with Professor Karl Schtigerl as volume editor and to present here a collection of 11 outstanding review articles written mainly by former students, associates, colleagues and friends of Wolf- Dieter Deckwer. The title of this special volume well reflects the research interests and sci- tific pursuit of Wolf-Dieter Deckwer during his more than 20 years’ work in the area of biochemical engineering, particularly during the last 15 years when he was the head of the Biochemical Engineering Division of GBF (German Nat- nal Research Center for Biotechnology). He has decisively pushed the devel- ment not only of "software tools" ranging from analytical means and mathe- tical models for monitoring and understanding cellular processes to gene expression systems for designing microorganisms, but also of "hardware tools" such as computer control systems, bioreaction and separation devices for eff- tively producing a variety of bioproducts on semi-production scale. New developments in some of these important tools in biochemical engineering are reviewed in articles included in this volume. Wolf-Dieter Deckwer was among the leading biochemical engineers who timely pointed out the necessity of applying these tools in an integrated manner for bioprocess development. By establishing "Integrated Bioprocess Development" as one of the GBF main - search topics as early as 1990 he also actively promoted this idea.

Author: Rajni Hatti-Kaul
Publisher: CRC Press
ISBN: 0824747593
Category : Science
Languages : en
Pages : 653

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Book Description
This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.

Author: Toshiomi Yoshida
Publisher: John Wiley & Sons
ISBN: 3527800603
Category : Science
Languages : en
Pages : 656

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Book Description
A comprehensive overview of the topic, highlighting recent developments, ongoing research trends and future directions. Experts from Europe, Asia and the US cover five core areas of imminent importance to the food, feed, pharmaceutical and water treatment industries in terms of sustainable and innovative processing and production. In the field of enzyme engineering, they summarize historic developments and provide an overview of molecular enzyme engineering, while also discussing key principles of microbial process engineering, including chapters on process development and control. Further sections deal with animal and plant cell culture engineering. The final section of the book deals with environmental topics and highlights the application of bioengineering principles in waste treatment and the recovery of valuable resources. With its cutting-edge visions, extensive discussions and unique perspectives, this is a ready reference for biotechnologists, bioengineers, bioengineers, biotechnological institutes, and environmental chemists.

Author: Mohamed Al-Rubeai
Publisher: Springer
ISBN: 3319103202
Category : Medical
Languages : en
Pages : 766

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Book Description
​Animal cells are the preferred “cell factories” for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies. This book is designed to serve as a comprehensive review of animal cell culture, covering the current status of both research and applications. For the student or R&D scientist or new researcher the protocols are central to the performance of cell culture work, yet a broad understanding is essential for translation of laboratory findings into the industrial production. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field to produce state-of-the-art collection of current research. A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential reading for everyone working in cell culture and is a recommended volume for all biotechnology libraries.