Author: Abd Elrazaq WreikatPublisher:
ISBN:
Category :
Languages : en
Pages : 5
Book Description
Application of Flow Cytometry in the Diagnosis of Primary Immunodeficiency Disease (PID)
Author: Abd Elrazaq WreikatApplication of Cytometry in Primary Immunodeficiencies
Author: Tomas KalinaPublisher: Frontiers Media SA
ISBN: 2889636941
Category :
Languages : en
Pages : 261
Book Description
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Cell Interaction
Author: Bhawana SinghPublisher: BoD – Books on Demand
ISBN: 183968416X
Category : Medical
Languages : en
Pages : 230
Book Description
This book discusses contemporary ideas on different molecular and immunological aspects of diseases. Different signaling mediators drive the production of messenger molecules that mediate their action, leading to the elicitation/suppression of immune responses. It provides a balanced approach to the study of different molecular phenomena that eventually drive infection outcomes and that can be manipulated for therapeutic benefits.
Flow Cytometry Applied to the Diagnosis of Primary Immunodeficiencies
Author: Mónica Martínez GalloPublisher:
ISBN:
Category : Science
Languages : en
Pages : 0
Book Description
Primary immunodeficiencies are the result of biological defects associated with functional immune abnormalities. It consists of a group of disorders showing a higher incidence and severity of infections, expression of immunological dysregulation such as inflammation and lymphoproliferation. The immunophenotyping and in vitro functional characterization of immunodeficient patients contribute, together with the clinical aspects, to define the underlying immune defect particularities. Flow cytometry applications in primary immunodeficiency assessment are multiple and include the study of a wide range of specific cell lymphocyte subpopulations. This chapter describes the main techniques used in the diagnosis of a wide variety of primary immunodeficiencies, in which intracellular proteins or activation markers involved in immunity are evaluated, as well as functional proliferation, cytokine production, phosphorylation of transcription factors, cytotoxic and degranulation capacity. Flow cytometry is a tool that allows rapid and accurate evaluation of multiple lymphocyte populations and immunological function, and this information is essential for the diagnosis and evaluation of patients with primary immunodeficiencies.
Clinical Cases in Primary Immunodeficiency Diseases
Author: Asghar AghamohammadiPublisher: Springer Science & Business Media
ISBN: 3642317855
Category : Medical
Languages : en
Pages : 392
Book Description
Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the invaluable cooperation of more than 40 scientists in the field of immunodeficiency. They focus both on the presenting features of patients with PIDs and on the required further investigation and management. Each of the numbered cases is followed by the questions, their answers, and additional discussion. Each question focuses on a particular aspect of the PID under consideration, and the topics covered include clinical diagnosis, laboratory findings, molecular mechanisms, and therapy.
Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases with Immune Dysregulation
Author: Otavio Cabral-MarquesPrimary Immunodeficiency Diseases
Author: Nima RezaeiPublisher: Springer
ISBN: 3662529092
Category : Medical
Languages : en
Pages : 593
Book Description
The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.
Primary Immunodeficiency
Author: Renfen ChenPublisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
Book Description
Primary immunodeficiency (PID) is a large group of rare diseases present with chronic, serious, or life-threatening infections and other immune complications caused by defects or dysfunction of human immune system. Unlike secondary immunodeficiency acquired from an environmental factor or other medical conditions, PIDs are initiated by genetic defects. PIDs are divided into innate/adaptive immunodeficiencies, phagocytic deficiencies, complement deficiencies, and immune dysregulation. Due to the heterogeneous nature of the clinical presentations, diagnosis of PIDs can be of significant challenge. Review of clinical history and physical examination is important for raising initial suspicion of PIDs, whereas laboratory testing is essential to establish a diagnosis. Laboratory investigation includes the assessment of antibody and cellular response, as well as evaluation of the phagocytic and complement system. Flow cytometry and genetic assays are generally served as confirmation tools to validate a diagnosis. The recent exponential increase of genetic analysis has facilitated the identification of known and novel mutations. The advances in understanding of the immune system, development of novel cellular and molecular methodologies, and increased clinical awareness have led to significant improvement of disease management and clinical outcome for these diseases.
Clinical Cases in Primary Immunodeficiency Diseases
Author: Asghar AghamohammadiPublisher: Springer
ISBN: 9783642317866
Category : Medical
Languages : en
Pages : 380
Book Description
Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the invaluable cooperation of more than 40 scientists in the field of immunodeficiency. They focus both on the presenting features of patients with PIDs and on the required further investigation and management. Each of the numbered cases is followed by the questions, their answers, and additional discussion. Each question focuses on a particular aspect of the PID under consideration, and the topics covered include clinical diagnosis, laboratory findings, molecular mechanisms, and therapy.
Flow Cytometry Protocols
Author: Teresa S. HawleyPublisher: Springer Nature
ISBN: 107163738X
Category :
Languages : en
Pages : 460
Book Description