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Antiemetic Therapy

Antiemetic Therapy PDF Author: Josef Donnerer
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805575475
Category : Medical
Languages : en
Pages : 241

Book Description
Prevention and treatment of nausea and emesis are important issues in a patients wellbeing in the clinical setting as well as for the outpatient. Various and still partly unresolved pathomechanisms play a role in nausea and emesis in humans. It is therefore important to compare results from preclinical research in animal models with results from clinical studies. This book combines an overview of the preclinical research on antiemetic drugs and state-of-the art reviews on the prevention and treatment of nausea and emesis. Established treatment regimens are compared with new interesting compounds in clinical trials. An up-to-date overview of the selection of antiemetic drugs, of their dosage and route of administration is given for clinical conditions such as emetogenic anti-cancer chemotherapy, radiation therapy, surgery, and hyperemesis gravidarum. The treatment of nausea and emesis in opioid therapy and in motion sickness is equally outlined. Whereas this book should serve the clinician in making the right choice for every patients need, it also pays significant attention to the interests of scientists in the fields of oncology, nutrition, gastroenterology, obstetrics and gynecology as well as anaesthesia.

Antiemetic Therapy

Antiemetic Therapy PDF Author: Josef Donnerer
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805575475
Category : Medical
Languages : en
Pages : 241

Book Description
Prevention and treatment of nausea and emesis are important issues in a patients wellbeing in the clinical setting as well as for the outpatient. Various and still partly unresolved pathomechanisms play a role in nausea and emesis in humans. It is therefore important to compare results from preclinical research in animal models with results from clinical studies. This book combines an overview of the preclinical research on antiemetic drugs and state-of-the art reviews on the prevention and treatment of nausea and emesis. Established treatment regimens are compared with new interesting compounds in clinical trials. An up-to-date overview of the selection of antiemetic drugs, of their dosage and route of administration is given for clinical conditions such as emetogenic anti-cancer chemotherapy, radiation therapy, surgery, and hyperemesis gravidarum. The treatment of nausea and emesis in opioid therapy and in motion sickness is equally outlined. Whereas this book should serve the clinician in making the right choice for every patients need, it also pays significant attention to the interests of scientists in the fields of oncology, nutrition, gastroenterology, obstetrics and gynecology as well as anaesthesia.

The Essence of Analgesia and Analgesics

The Essence of Analgesia and Analgesics PDF Author: Raymond S. Sinatra
Publisher: Cambridge University Press
ISBN: 1139491989
Category : Medical
Languages : en
Pages : 551

Book Description
The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Perugia Consensus Conference on Antiemetic Therapy

Perugia Consensus Conference on Antiemetic Therapy PDF Author: Richard J. Gralla
Publisher: Springer Science & Business Media
ISBN: 3642721370
Category : Medical
Languages : en
Pages : 121

Book Description
In the last decade, important progress has been achieved in the prevention of chemotherapy-induced nausea and vomiting, in particular since the introduction of 5-HT3 antagonists which, when used in combination with steroids, can assure significant protection in the majority of patients. Nonetheless, for some relevant clinical problems there still is no satisfactory answer, and there are major differences in clinical practice regarding antiemetic use. This volume contains the results of the fifth Perugia International Cancer Conference which was organized in 8 sessions, a consensus document was prepared for each session forming a useful basis for future developments.

Essential Clinical Anesthesia

Essential Clinical Anesthesia PDF Author: Charles Vacanti
Publisher: Cambridge University Press
ISBN: 1139498401
Category : Medical
Languages : en
Pages : 1191

Book Description
The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

Introduction to Basics of Pharmacology and Toxicology

Introduction to Basics of Pharmacology and Toxicology PDF Author: Abialbon Paul
Publisher: Springer Nature
ISBN: 9813360097
Category : Medical
Languages : en
Pages : 1156

Book Description
This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Baloh and Honrubia's Clinical Neurophysiology of the Vestibular System

Baloh and Honrubia's Clinical Neurophysiology of the Vestibular System PDF Author: Robert W. Baloh MD Faan
Publisher: Contemporary Neurology
ISBN: 019538783X
Category : Language Arts & Disciplines
Languages : en
Pages : 478

Book Description
This completely reorganized and expanded fourth edition covers the rapid advances that have occurred in the basicand clinical vestibular sciences in the past 10 years. Recent breakthroughs in our understanding of the molecular mechanisms of peripheral transduction and central processing within the vestibular system are reviewed. The authors discuss the differential diagnosis of dizziness of both vestibular and non-vestibular etiology and demonstrate bedside tests of vestibular function.

Essential Clinical Anesthesia Review

Essential Clinical Anesthesia Review PDF Author: Linda S. Aglio
Publisher: Cambridge University Press
ISBN: 1316062287
Category : Medical
Languages : en
Pages : 577

Book Description
This concise, evidence-based board review book, organized according to the ABA keyword list, covers all the fundamental concepts needed to pass written and re-certification board examinations. Each chapter begins with a case scenario or clinical problem from everyday practice, followed by concise discussion and clinical review questions and answers. Discussion progresses logically from preoperative assessment and intraoperative management to postoperative pain management, enhancing the reader's knowledge and honing diagnostic and clinical management skills. New guidelines and recently developed standards of care are also covered. Serving as a companion to the popular textbook Essential Clinical Anesthesia, this resourceful work reflects the clinical experiences of anesthesia experts at Harvard Medical School as well as individually known national experts in the field of anesthesiology. This practical review is an invaluable resource for anesthesiologists in training and practice, whether studying for board exams or as part of continuing education and ABA recertification.

Prevention of Nausea and Vomiting in Cancer Patients

Prevention of Nausea and Vomiting in Cancer Patients PDF Author: Matti Aapro
Publisher: Springer Science & Business Media
ISBN: 190767358X
Category : Medical
Languages : en
Pages : 63

Book Description
Treatment tolerance is a challenge for most cancer patients, and it is therefore essential that healthcare professionals (HCPs) are quick to recognize adverse events and implement management strategies to address them. Prevention of Nausea and Vomiting in Cancer Patients provides comprehensive guidance on managing nausea and vomiting, which are common and often severe adverse events experienced by patients receiving chemotherapy and radiotherapy. The book refers to the latest American Society of Clinical Oncology (ASCO), European Society of Medical Oncology (ESMO), and Multinational Association for Supportive Care in Cancer (MASCC) guidelines and will be a useful resource for oncologists, oncology fellows, general physicians, and other HCPs wishing to learn more about the effective management of chemotherapy-and radiotherapy-induced nausea and vomiting in cancer patients.

Anesthetic Pharmacology

Anesthetic Pharmacology PDF Author: Alex S. Evers
Publisher: Cambridge University Press
ISBN: 1139497022
Category : Medical
Languages : en
Pages : 2902

Book Description
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Key Heterocycle Cores for Designing Multitargeting Molecules

Key Heterocycle Cores for Designing Multitargeting Molecules PDF Author: Om Silakari
Publisher: Elsevier
ISBN: 0081021054
Category : Science
Languages : en
Pages : 436

Book Description
Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases