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Author: Jochen Kuhlmann Publisher: Springer Science & Business Media ISBN: 3662091275 Category : Medical Languages : en Pages : 750
Book Description
Diabetes continues to spread worldwide. Traditionally diabetes in adults has not been considered a serious life-threatening disease. This attitude needs to be changed, however, since the complications associated with the adult form of diabetes affect almost every organ system. The high morbidity and mortality of Non-Insulin-Dependent Diabetes Mellitus (NIDDM) suggest that current treatment strategies are unsatisfactory, pointing to an urgent need for new therapeutic approaches. This volume provides a comprehensive description and evaluation of recently obtained and previously unpublished data written by leading experts in the field, together with a discussion of antidiabetics under development and new approaches for the management of type 2 diabetes.
Author: Jochen Kuhlmann Publisher: Springer Science & Business Media ISBN: 3662091275 Category : Medical Languages : en Pages : 750
Book Description
Diabetes continues to spread worldwide. Traditionally diabetes in adults has not been considered a serious life-threatening disease. This attitude needs to be changed, however, since the complications associated with the adult form of diabetes affect almost every organ system. The high morbidity and mortality of Non-Insulin-Dependent Diabetes Mellitus (NIDDM) suggest that current treatment strategies are unsatisfactory, pointing to an urgent need for new therapeutic approaches. This volume provides a comprehensive description and evaluation of recently obtained and previously unpublished data written by leading experts in the field, together with a discussion of antidiabetics under development and new approaches for the management of type 2 diabetes.
Book Description
En France, la prévalence du diabète est de 1,4% à 2,1% de la population. Le diabète de type 2 représente 85% de la population diabétique. Longtemps on disposait de seulement 2 types d'antidiabétique oral : les biguanides et les sulfamides hypoglycémiants. Mais ces dix dernières années, cette classe thérapeutique s'est enrichie de nouvelles molécules : les glinides, les inhibiteurs des alpha-glucosidases et les thiazolidinediones ou glitazones. On peut ainsi classer les antidiabétiques oraux par leur mode d'action :Réduction de l'insulinorésistance : les Biguanides et les thiazolidinedies. Stimulation de la sécrétion endogène de l'insuline : les Sulfamides hypoglycémiants et les Glinides. Retard de l'absorption des hydrates de carbone au niveau gastro-intestinal : les Inhibiteurs des alpha-glucosidases. On fera le point sur les différents mécanismes d'action des différents antidiabétiques oraux, de leurs propriétés et leurs interactions médicamenteuses.
Author: Charlene Freeman Publisher: PHC Publishing Group ISBN: 0972214755 Category : Diabetes Languages : en Pages : 74
Book Description
This book will be helpful for any health care professional assisting the patient with diabetes to reach their target goals. The various oral medications and their mechanisms, as well as the types and regimens of the various insulins are discussed. Reaching target goals has been shown to prevent the acute (hypoglycemia and hyperglycemia) and chronic (retinopathy, nephropathy, neuropathy, coronary heart disease and stroke) complications of diabetes. Therefore, it is critical that healthcare professionals have the knowledge to assist their patients in meeting their diabetes goals. This resourceful tool can be yours for just $14.95. Additionally, nurses will be able to earn continuing education contact hours after reading this book.
Author: Samuel Dagogo-Jack Publisher: Oxford University Press ISBN: 0199749558 Category : Medical Languages : en Pages : 106
Book Description
More than 23 million Americans currently have diabetes and approximately 54 million have pre-diabetes. People with diabetes often also require medications for several co-morbid conditions (including hypertension, dyslipidemia, depression, heart disease, pain syndromes). Yet, a vast literature abounds on the potential adverse effects of numerous medications on glucose metabolism. Thus, genuine clinical concern exists that certain medications used for treatment of co-morbid conditions and other indications (such as hormone replacement, contraception, infections) might worsen glycemic control in diabetic patients or trigger diabetes in others. These concerns influence therapeutic decisions in a manner that sometimes emphasizes avoidance of possible dysglycemia over effective control of the co-morbid conditions. The same concerns may also weigh against the otherwise appropriate use of necessary medications. The purpose of this concise book is to provide clinicians with actionable knowledge regarding the effects of various medications on glucose regulation and diabetes risk. Beginning with a brief overview of diabetes pathophysiology, the different drugs have been organized by class, and the scientific evidence for the diabetes risk and possible mechanisms have been presented for each drug. The agents discussed include widely prescribed medication classes: antibiotics, antidepressants, antihypertensives, bronchodilators, estrogens and oral contraceptives, glucocorticoids, lipid-lowering agents, NSAIDs, and thyroid hormone. Although less widely prescribed than the foregoing list, atypical antipsychotics, HIV antiretrovirals, immunomodulatory agents, and human growth hormone, have also been included because of the interest generated by their link to diabetes risk. In addition to medications used in ambulatory practice, this work includes a discussion of total parenteral nutrition (TPN)-induced hyperglycemia, which is associated with increased morbidity and mortality among hospitalized patients. For completeness, an account of the growing link between use of recreational drugs (alcohol, nicotine, cannabinoids, opioids, cocaine) and glucose abnormalities has been included, because of the possible intersection between these addictive agents and the growing diabetes epidemic. With some medications, the data presented should help debunk myths, clarify misperceptions and provide reassurance to the practicing clinicians. Wherever the evidence supports increased diabetes risk, clear suggestions are given on how to reduce the risk. This book serves two essential functions: to enable clinicians to confidently prescribe therapeutic regimens that embody the best risk-benefit profile with regard to glycemia, and to equip them with the know-how for preventing and managing drug-induced hyperglycemia
Author: Miles Fisher Publisher: John Wiley & Sons ISBN: 1119785022 Category : Medical Languages : en Pages : 404
Book Description
DIABETES DRUG NOTES Diabetes is becoming more common in both older and younger generations and in keeping with this escalation in cases, there are an ever increasing number of drugs and drug classes that are suitable to treat hyperglycaemia. In a unique blend of diabetes practice, clinical pharmacology, and cardiovascular medicine, Diabetes Drug Notes describes the principles of clinical pharmacology with regards to diabetes prescribing. Each drug class for the treatment of diabetes is covered in detail, along with the effect on the cardiovascular and renal systems caused by each drug. Building upon the success of their “Drug Notes” series for Practical Diabetes and their “Drugs for Diabetes” series in the British Journal of Cardiology, the team of experts focuses on the glycaemic management of type 1 and type 2 diabetes, with other effects of antidiabetic drugs covered as well. Diabetes Drug Notes also includes: Comprehensive and up-to-date coverage of the drugs for the glycaemic management of patients with type 1 or type 2 diabetes Expert reflection on prescribing considerations for special groups, as well as common pitfalls in prescribing Detailed case histories to illustrate relevant information Summaries of recent guidelines related to diabetic intervention Diabetes Drug Notes is a user-friendly guide for a general diabetes medical, nursing, and pharmacology readership, as well as those who support them.
Author: Romesh Khardori Publisher: Jaypee Brothers Medical Publishers ISBN: 9389188350 Category : Medical Languages : en Pages : 216
Book Description
This book is designed to be a ready reckoner on commonly used medications for the treatment of diabetes mellitus. Divided into 17 sections, topics include incretin-based therapies, insulin, chloroquine, metformin, colesevelam, drugs targeting renal excretion of glucose, management of dyslipidaemia, and more. The book concludes with discussion on associated comorbidities such as hypertension and diabetes in the elderly. Drug classes featured are all approved in-line with FDA (United States Food and Drug Administration) guidelines. Authored by recognised, US-based experts in the field, the comprehensive text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to pharmaceutical treatments for diabetes mellitus Features approved drugs in-line with FDA (United States Food and Drug Administration) guidelines Includes discussion on commonly associated comorbidities such as hypertension, and diabetes in the elderly Internationally recognised, US-based author team
Author: Kanti Bhooshan Pandey Publisher: John Wiley & Sons ISBN: 1119983339 Category : Science Languages : en Pages : 356
Book Description
Natural Products and their Bioactives in Antidiabetic Drug Discovery Enables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetes Natural Products and Their Bioactives in Antidiabetic Drug Discovery provides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters. Part one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds. Written by a global team of experts in the field, Natural Products and their Bioactives in Antidiabetic Drug Discovery covers sample topics such as: Obesity risk factor in patients with T1DM and possible role of nutritional therapy in its management Use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM Effectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials Implementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds Various antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy Effects of natural products on genetics of gestational diabetes With comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, Natural Products and Their Bioactives in Antidiabetic Drug Discovery is an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology.
Author: Publisher: Elsevier ISBN: 0080526705 Category : Medical Languages : en Pages : 255
Book Description
Volume 27, the first thematic volume in the Series, provides an overview of present knowledge with regard to the pharmacological and clinical aspects of antidiabetic drugs. It aims to stimulate further consideration of possible concepts in the development of new antidiabetic drugs.
Author: Jochen Kuhlmann
Author: Jochen Kuhlmann
Author: Sandra Picard
Author: Charlene Freeman
Author: Samuel Dagogo-Jack
Author: Miles Fisher
Author: Romesh Khardori
Author: Kanti Bhooshan Pandey
Author: 
Author: Andrew Krentz
Author: Jens Møller