Author: A.P. Ball
Publisher: Springer
ISBN: 9780852005057
Category : Medical
Languages : en
Pages : 163
Book Description
Since the first edition there has been a great demand for this book. It has been revised to include up-to-date and new entries covering recent additions to the availa ble drugs. As well there are now sections on clinical situations, or types of patient, presenting especial problems. The authors hope this new material will enhance the effectiveness of the book as a guide to this rapidly advancing and changing therapeutic situation. A.P.B. J.A.G. J.McC.M. July, 1978 v Contents I. Antibacterial Drugs 1.1 Mechanisms of Action I .2 Side Effects and Toxicity 2 2. The Sulphonamides .............................. . 2 2.1 Antibacterial Activity .... 2 2.2 Mode of Antibacterial Action 2.3 Pharmacology 3 2.4 Therapeutic Indications ... 4 2.5 Dosage ....................... . 4 2.5.1 Short Acting Sulphonamides ..................... . 4 2.5.2 Long Acting Sulphonamides 5 2.5.3 Non-absorbable Sulphonamides 5 2.6 Side Effects and Toxicity 5 2.6.1 Nephrotoxicity ............................... . 5 2.6.2 Haematological Abnormalities 5 2.6.3 Pulmonary Disease .. . 5 2.6.4 Hypersensitivity .................................................. . 6 2.7 Drug Interactions ... 6 3. The Natural Penicillins - Benzylpenicillin (Penicillin G) and Phenoxymetbylpe- cillin (Penicillin V) .......................... . ..................... .
Antibacterial Drugs Today
Author: A.P. Ball
Publisher: Springer
ISBN: 9780852005057
Category : Medical
Languages : en
Pages : 163
Book Description
Since the first edition there has been a great demand for this book. It has been revised to include up-to-date and new entries covering recent additions to the availa ble drugs. As well there are now sections on clinical situations, or types of patient, presenting especial problems. The authors hope this new material will enhance the effectiveness of the book as a guide to this rapidly advancing and changing therapeutic situation. A.P.B. J.A.G. J.McC.M. July, 1978 v Contents I. Antibacterial Drugs 1.1 Mechanisms of Action I .2 Side Effects and Toxicity 2 2. The Sulphonamides .............................. . 2 2.1 Antibacterial Activity .... 2 2.2 Mode of Antibacterial Action 2.3 Pharmacology 3 2.4 Therapeutic Indications ... 4 2.5 Dosage ....................... . 4 2.5.1 Short Acting Sulphonamides ..................... . 4 2.5.2 Long Acting Sulphonamides 5 2.5.3 Non-absorbable Sulphonamides 5 2.6 Side Effects and Toxicity 5 2.6.1 Nephrotoxicity ............................... . 5 2.6.2 Haematological Abnormalities 5 2.6.3 Pulmonary Disease .. . 5 2.6.4 Hypersensitivity .................................................. . 6 2.7 Drug Interactions ... 6 3. The Natural Penicillins - Benzylpenicillin (Penicillin G) and Phenoxymetbylpe- cillin (Penicillin V) .......................... . ..................... .
Publisher: Springer
ISBN: 9780852005057
Category : Medical
Languages : en
Pages : 163
Book Description
Since the first edition there has been a great demand for this book. It has been revised to include up-to-date and new entries covering recent additions to the availa ble drugs. As well there are now sections on clinical situations, or types of patient, presenting especial problems. The authors hope this new material will enhance the effectiveness of the book as a guide to this rapidly advancing and changing therapeutic situation. A.P.B. J.A.G. J.McC.M. July, 1978 v Contents I. Antibacterial Drugs 1.1 Mechanisms of Action I .2 Side Effects and Toxicity 2 2. The Sulphonamides .............................. . 2 2.1 Antibacterial Activity .... 2 2.2 Mode of Antibacterial Action 2.3 Pharmacology 3 2.4 Therapeutic Indications ... 4 2.5 Dosage ....................... . 4 2.5.1 Short Acting Sulphonamides ..................... . 4 2.5.2 Long Acting Sulphonamides 5 2.5.3 Non-absorbable Sulphonamides 5 2.6 Side Effects and Toxicity 5 2.6.1 Nephrotoxicity ............................... . 5 2.6.2 Haematological Abnormalities 5 2.6.3 Pulmonary Disease .. . 5 2.6.4 Hypersensitivity .................................................. . 6 2.7 Drug Interactions ... 6 3. The Natural Penicillins - Benzylpenicillin (Penicillin G) and Phenoxymetbylpe- cillin (Penicillin V) .......................... . ..................... .
Antibacterial Drugs Today
Author: A.P. Ball
Publisher: Springer Science & Business Media
ISBN: 9401180040
Category : Medical
Languages : en
Pages : 175
Book Description
Since the first edition there has been a great demand for this book. It has been revised to include up-to-date and new entries covering recent additions to the availa ble drugs. As well there are now sections on clinical situations, or types of patient, presenting especial problems. The authors hope this new material will enhance the effectiveness of the book as a guide to this rapidly advancing and changing therapeutic situation. A.P.B. J.A.G. J.McC.M. July, 1978 v Contents I. Antibacterial Drugs 1.1 Mechanisms of Action I .2 Side Effects and Toxicity 2 2. The Sulphonamides .............................. . 2 2.1 Antibacterial Activity .... 2 2.2 Mode of Antibacterial Action 2.3 Pharmacology 3 2.4 Therapeutic Indications ... 4 2.5 Dosage ....................... . 4 2.5.1 Short Acting Sulphonamides ..................... . 4 2.5.2 Long Acting Sulphonamides 5 2.5.3 Non-absorbable Sulphonamides 5 2.6 Side Effects and Toxicity 5 2.6.1 Nephrotoxicity ............................... . 5 2.6.2 Haematological Abnormalities 5 2.6.3 Pulmonary Disease .. . 5 2.6.4 Hypersensitivity .................................................. . 6 2.7 Drug Interactions ... 6 3. The Natural Penicillins - Benzylpenicillin (Penicillin G) and Phenoxymetbylpe- cillin (Penicillin V) .......................... . ..................... .
Publisher: Springer Science & Business Media
ISBN: 9401180040
Category : Medical
Languages : en
Pages : 175
Book Description
Since the first edition there has been a great demand for this book. It has been revised to include up-to-date and new entries covering recent additions to the availa ble drugs. As well there are now sections on clinical situations, or types of patient, presenting especial problems. The authors hope this new material will enhance the effectiveness of the book as a guide to this rapidly advancing and changing therapeutic situation. A.P.B. J.A.G. J.McC.M. July, 1978 v Contents I. Antibacterial Drugs 1.1 Mechanisms of Action I .2 Side Effects and Toxicity 2 2. The Sulphonamides .............................. . 2 2.1 Antibacterial Activity .... 2 2.2 Mode of Antibacterial Action 2.3 Pharmacology 3 2.4 Therapeutic Indications ... 4 2.5 Dosage ....................... . 4 2.5.1 Short Acting Sulphonamides ..................... . 4 2.5.2 Long Acting Sulphonamides 5 2.5.3 Non-absorbable Sulphonamides 5 2.6 Side Effects and Toxicity 5 2.6.1 Nephrotoxicity ............................... . 5 2.6.2 Haematological Abnormalities 5 2.6.3 Pulmonary Disease .. . 5 2.6.4 Hypersensitivity .................................................. . 6 2.7 Drug Interactions ... 6 3. The Natural Penicillins - Benzylpenicillin (Penicillin G) and Phenoxymetbylpe- cillin (Penicillin V) .......................... . ..................... .
Biography of Resistance
Author: Muhammad H. Zaman
Publisher: HarperCollins
ISBN: 0062862987
Category : Science
Languages : en
Pages : 300
Book Description
Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis. In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns. The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe. Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.
Publisher: HarperCollins
ISBN: 0062862987
Category : Science
Languages : en
Pages : 300
Book Description
Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis. In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns. The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe. Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.
The Antibiotic Era
Author: Scott H. Podolsky
Publisher: JHU Press
ISBN: 1421415933
Category : Medical
Languages : en
Pages : 324
Book Description
During the post-World War II "wonder drug" revolution, antibiotics were viewed as a panacea for mastering infectious disease. This book narrates the far-reaching history of antibiotics, focusing particularly on reform efforts that attempted to fundamentally change how antibiotics are developed and prescribed
Publisher: JHU Press
ISBN: 1421415933
Category : Medical
Languages : en
Pages : 324
Book Description
During the post-World War II "wonder drug" revolution, antibiotics were viewed as a panacea for mastering infectious disease. This book narrates the far-reaching history of antibiotics, focusing particularly on reform efforts that attempted to fundamentally change how antibiotics are developed and prescribed
Treating Infectious Diseases in a Microbial World
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309180686
Category : Medical
Languages : en
Pages : 102
Book Description
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Publisher: National Academies Press
ISBN: 0309180686
Category : Medical
Languages : en
Pages : 102
Book Description
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Antibiotic Drug Resistance
Author: José-Luis Capelo-Martínez
Publisher: John Wiley & Sons
ISBN: 1119282527
Category : Medical
Languages : en
Pages : 730
Book Description
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Publisher: John Wiley & Sons
ISBN: 1119282527
Category : Medical
Languages : en
Pages : 730
Book Description
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Pharmacokinetics and Pharmacodynamics
Author: Patricia D. Kroboth
Publisher: Harvey Whitney Books Company
ISBN:
Category : Medical
Languages : en
Pages : 276
Book Description
Publisher: Harvey Whitney Books Company
ISBN:
Category : Medical
Languages : en
Pages : 276
Book Description
Antibiotics
Author: Claudio O. Gualerzi
Publisher: John Wiley & Sons
ISBN: 3527659706
Category : Medical
Languages : en
Pages : 549
Book Description
Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.
Publisher: John Wiley & Sons
ISBN: 3527659706
Category : Medical
Languages : en
Pages : 549
Book Description
Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.
Antibiotic Discovery and Development
Author: Thomas J. Dougherty
Publisher: Springer Science & Business Media
ISBN: 1461414008
Category : Medical
Languages : en
Pages : 1119
Book Description
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Publisher: Springer Science & Business Media
ISBN: 1461414008
Category : Medical
Languages : en
Pages : 1119
Book Description
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
The Use of Drugs in Food Animals
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309175771
Category : Medical
Languages : en
Pages : 276
Book Description
The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.
Publisher: National Academies Press
ISBN: 0309175771
Category : Medical
Languages : en
Pages : 276
Book Description
The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.