Author: Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
ANTIBACTERIAL AGENTS IN PRECLINICAL DEVELOPMENT: an Open Access Database
Author: 2020 Antibacterial agents in clinical and preclinical development
Author: Publisher: World Health Organization
ISBN: 9240021302
Category : Business & Economics
Languages : en
Pages : 76
Book Description
This report is the World Health Organization’s (WHO) fourth annual review of the clinical antibacterial pipeline, and the second review of the preclinical antibacterial pipeline. The WHO’s annual antibacterial pipeline report reviews antibiotics that are in the clinical stages of development as well as those in early development to assess the progress and gaps in relation to urgent threat of drug-resistance.The report evaluates the potential of these antibacterial candidates in development to address the most threatening drug-resistant bacteria as outlined in the WHO Bacterial Priority Pathogens List (WHO PPL). This report covers direct-acting small molecules and biological agents that are in development worldwide. In this fourth edition, the report includes for the first time a comprehensive overview of non-traditional antibacterial medicines. This report is part of the WHO’s efforts in global research and development (R&D) priority setting to contain antimicrobial resistance. All the data contained in this report can be downloaded from the WHO Global Observatory on Health R&D.
2021 Antibacterial agents in clinical and preclinical development
Author: World Health OrganizationPublisher: World Health Organization
ISBN: 9240047654
Category : Business & Economics
Languages : en
Pages : 104
Book Description
2021 ANTIBACTERIAL AGENTS IN CLINICAL AND PRECLINICAL DEVELOPMENT: an Overview and Analysis
Author: world health organizationPublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Antibiotic Discovery and Development
Author: Thomas J. DoughertyPublisher: Springer Science & Business Media
ISBN: 1461414008
Category : Medical
Languages : en
Pages : 1119
Book Description
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Bacterial vaccines in clinical and preclinical development 2021
Author: World Health OrganizationPublisher: World Health Organization
ISBN: 9240052453
Category : Medical
Languages : en
Pages : 92
Book Description
Target product profiles for needed antibacterial agents
Author: Publisher: World Health Organization
ISBN: 9240003894
Category : Medical
Languages : en
Pages : 32
Book Description
First meeting of the WHO Antifungal Expert Group on Identifying Priority Fungal Pathogens
Author: Publisher: World Health Organization
ISBN: 9240006354
Category : Medical
Languages : en
Pages : 18
Book Description
The End of an Antibiotic Era
Author: Rinke van den BrinkPublisher: Springer Nature
ISBN: 3030707237
Category : Medical
Languages : en
Pages : 322
Book Description
In this monograph, journalist Rinke van den Brink takes a closer look at the limitations and risks of today’s antibiotic use. Though all developed societies have grown accustomed to successfully treating bacterial infections with these wonder drugs, the author focuses on the increasing number of antibiotic-resistant infections. By examining recent mass outbreaks, readers will gain a better understanding of the global impact of antimicrobial resistance – one of the most serious public health threats today. Following this somewhat disquieting review of the status quo, interviews with a number of specialists provide an outlook on possible solutions. In a world that is more connected than ever, partnerships between different healthcare systems are becoming all the more important. Rinke van den Brink uses the example of a border-spanning collaboration between the Netherlands and Germany to demonstrate how effective lines of communication can be established. The book offers a wealth of useful background information for healthcare personnel. Not only does it share insights into the functional microbe-antibiotic relationship; it also discusses how clinics can effectively address outbreaks, helping readers to learn from past experiences and develop effective new strategies.
WHO fungal priority pathogens list to guide research, development and public health action
Author: World Health OrganizationPublisher: World Health Organization
ISBN: 9240060243
Category : Medical
Languages : en
Pages : 48
Book Description