Animal Models of Cognitive Aging and Dementia in the Rat : Problems and Perspectives PDF Download

Author: Arjan Blokland
Publisher:
ISBN: 9789052780337
Category : Animal experimentation
Languages : en
Pages : 142

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Author: Jennifer L. Bizon
Publisher: Springer Science & Business Media
ISBN: 1597454222
Category : Medical
Languages : en
Pages : 215

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Book Description
Significant improvements in lifestyle and medical science are leading to an ever increasing elderly population in the United States and other developed nations. The U.S census bureau estimates that the number of people over 65 will nearly double by 2030, and that the elderly will comprise nearly one-fifth of the world’s entire population within the next 20 years. In Animal Models of Human Cognitive Aging, Jennifer Bizon, Alisa Woods, and a panel of international authorities comprehensively discuss the use of animal models as a tool for understanding cognitive changes associated with the aging process. The book provides substantive background on the newest and most widely used animal models in studies of cognition and aging, while detailing the normal and pathological processes of brain aging of humans in relation to those models. Additional chapters comprehensively review frontal cortical deficits and executive function in primates as related to humans, and the use of transgenic modulation in mice to model Alzheimer’s and other age-related diseases. Groundbreaking and authoritative, Animal Models of Human Cognitive Aging provides a valuable resource for Neuroscientists, Gerontological Scientists and all aging medicine researchers, while serving as a primer for understanding current brain aging studies.

Author: Thomas Lincoln Casey
Publisher:
ISBN:
Category : MSH (Hormone)
Languages : en
Pages : 456

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Author: Ayanna K. Thomas
Publisher: Cambridge University Press
ISBN: 1108690742
Category : Psychology
Languages : en
Pages : 1019

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Book Description
Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.

Author: Alistair S. Burns
Publisher: Springer
ISBN: 1461568056
Category : Medical
Languages : en
Pages : 865

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Author: Joe L. Martinez, Jr.
Publisher: Elsevier
ISBN: 1483296652
Category : Psychology
Languages : en
Pages : 583

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Learning and Memory presents a comprehensive, up-to-date overview of brain*b1behavior relations as they bear on learning and memory. The structure of memory is investigated from a diversity of approaches, including anatomical, pharmacological, electrophysiological and lesions, and through the use of different populations, such as invertebrate, vertebrate, and human. Features updated chapters, including a new chapter on human cognitive processes and amnesia Presents multiple views of memory Examines a diversity of levels of analysis, methods of approach, and theoretical perspectives

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309368650
Category : Medical
Languages : en
Pages : 300

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Book Description
For most Americans, staying "mentally sharp" as they age is a very high priority. Declines in memory and decision-making abilities may trigger fears of Alzheimer's disease or other neurodegenerative diseases. However, cognitive aging is a natural process that can have both positive and negative effects on cognitive function in older adults - effects that vary widely among individuals. At this point in time, when the older population is rapidly growing in the United States and across the globe, it is important to examine what is known about cognitive aging and to identify and promote actions that individuals, organizations, communities, and society can take to help older adults maintain and improve their cognitive health. Cognitive Aging assesses the public health dimensions of cognitive aging with an emphasis on definitions and terminology, epidemiology and surveillance, prevention and intervention, education of health professionals, and public awareness and education. This report makes specific recommendations for individuals to reduce the risks of cognitive decline with aging. Aging is inevitable, but there are actions that can be taken by individuals, families, communities, and society that may help to prevent or ameliorate the impact of aging on the brain, understand more about its impact, and help older adults live more fully and independent lives. Cognitive aging is not just an individual or a family or a health care system challenge. It is an issue that affects the fabric of society and requires actions by many and varied stakeholders. Cognitive Aging offers clear steps that individuals, families, communities, health care providers and systems, financial organizations, community groups, public health agencies, and others can take to promote cognitive health and to help older adults live fuller and more independent lives. Ultimately, this report calls for a societal commitment to cognitive aging as a public health issue that requires prompt action across many sectors.

Author: Carolyn K. Rovee-Collier
Publisher: John Benjamins Publishing
ISBN: 9781556197246
Category : Psychology
Languages : en
Pages : 340

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Book Description
This is the only book that examines the theory and data on the development of implicit and explicit memory. It first describes the characteristics of implicit and explicit memory (including conscious recollection) and tasks used with adults to measure them. Next, it reviews the brain mechanisms thought to underlie implicit and explicit memory and the studies with amnesics that initially prompted the search for different neuroanatomically-based memory systems. Two chapters review the Jacksonian (first in, last out) principle and empirical evidence for the hierarchical appearance and dissolution of two memory systems in animal models (rats, nonhuman primates), children, and normal/amnesic adults. Two chapters examine memory tasks used with human infants and evidence of implicit and explicit memory during early infancy. Three final chapters consider structural and processing accounts of adult memory dissociations, their applicability to infant memory dissociations, and implications of infant data for current concepts of implicit and explicit memory. (Series B)

Author: Joe L. Martinez Jr.
Publisher: Elsevier
ISBN: 0080537405
Category : Science
Languages : en
Pages : 473

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Book Description
Neurobiology of Learning and Memory provides an excellent overview of current information on this fast-growing field of neurobiology. The contents have been structured for use as a course text or as a handy resource for researchers in neuro- and cognitive psychology. It discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, as well as changes in learning and memory with age. Neurobiology of Learning and Memory also includes research on invertebrates and vertebrates, presenting basics in anatomy and development along with computational models. It is written in an easy-to-follow format with summaries at the end of each chapter. Key Features* Provides an overview of information on the neurobiology of learning and memory* Discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, and changes in learning and memory with age* Includes research on invertebrates and vertebrates* Gives basics on anatomy and development* Written for easy comprehension with chapter summaries

Author: Deborah L. Colbern
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 456

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