Author: Karen L. WahlPublisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Analysis of Hazardous Biological Materials by MALDI Mass Spectrometry
Author: Karen L. WahlAnalysis of Hazardous Biological Material by MALDI Mass Spectrometry
Author: Publisher:
ISBN:
Category :
Languages : en
Pages : 62
Book Description
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-MS) has become a valuable tool for analyzing microorganisms. The speed with which data can be obtained from MALDI-MS makes this a potentially important tool for biological health hazard monitoring and forensic applications. The excitement in the mass spectrometry community in this potential field of application is evident by the expanding list of research laboratories pursuing development of MALDI-MS for bacterial identification. Numerous research groups have demonstrated the ability to obtain unique MALDI-MS spectra from intact bacterial cells and bacterial cell extracts. The ability to differentiate strains of the same species has been investigated. Reproducibility of MALDI-MS spectra from bacterial species under carefully controlled experimental conditions has also been demonstrated. Wang et al. have reported on interlaboratory reproducibility of the MALDI-MS analysis of several bacterial species. However, there are still issues that need to be addressed, including the careful control of experimental parameters for reproducible spectra and selection of optimal experimental parameters such as solvent and matrix.
Mass Spectrometry of Biological Materials, Second Edition
Author: Barbara S. LarsenPublisher: CRC Press
ISBN: 9780824701574
Category : Science
Languages : en
Pages : 490
Book Description
Second Edition provides up-to-the-minute discussions on the application of mass spectrometry to the biological sciences. Shows how and why experiments are performed and furnishes details to facilitate duplication of results.
Sample Preparation in Biological Mass Spectrometry
Author: Alexander R. IvanovPublisher: Springer Science & Business Media
ISBN: 9400708289
Category : Science
Languages : en
Pages : 1081
Book Description
The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.
Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism
Author: Joseph BanoubPublisher: Springer
ISBN: 9401792380
Category : Science
Languages : en
Pages : 290
Book Description
This NATO-ASI installment is designed to provide an advanced overview for doctoral and post-doctoral candidates of the state-of-the-art technologies for bio-detection. The main objective of the work aims at providing readers with the latest developments necessary to successfully understand the CBRN Agents and their associated biotechnologies. The core methods focused on are mass spectrometry (including chromatographic and electrophoretic separation) and comparisons to spectroscopic, immunological and molecular analysis of chemical, biological and nuclear agents.
Preparation, Acquisition, and Analysis of Biological Samples Using MALDI-TOF Mass Spectrometry
Author: Josué A. AlfaroPublisher:
ISBN:
Category : Genomes
Languages : en
Pages : 94
Book Description
Fundamental Studies of Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry (MALDI-TOF/MS) and Its Applications to the Analysis of Biological Materials
Author: Yongdong ZhuMethodological Advances of MALDI Mass Spectrometry-Based Techniques in Organic and Biomedical Analysis
Author: Cheng GuoPublisher: Frontiers Media SA
ISBN: 2889764362
Category : Science
Languages : en
Pages : 120
Book Description
Mass Spectrometry of Biological Materials
Author: Charles N. McEwenPublisher:
ISBN:
Category : Science
Languages : en
Pages : 544
Book Description
Mass Spectrometry for Metabolomics
Author: Raúl González-DomínguezPublisher: Springer Nature
ISBN: 107162699X
Category : Science
Languages : en
Pages : 277
Book Description
This detailed volume provides a comprehensive overview of state-of-the-art metabolomics methods based on mass spectrometry (MS), and their application in food, nutrition, and biomedical research. The chapters assembled herein cover hot topics related to sample preparation, chromatographic and electrophoretic separation, MS-based analysis, as well as data processing and analysis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mass Spectrometry for Metabolomics serves as a timely guide for chemists, biochemists, biologists, nutritionists, clinicians, and other experts working in the growing and exciting field of metabolomics.