Author: Anissa Wai-Sinn WongPublisher:
ISBN:
Category :
Languages : en
Pages : 256
Book Description
Analysis of Biomolecules by Matrix-assisted Laser Desorption/ionization-fourier Transform Mass Spectrometry
Author: Anissa Wai-Sinn WongPublisher:
ISBN:
Category :
Languages : en
Pages : 256
Book Description
Matrix Assisted Laser Desorption Ionization with External Source Quadrupole Fourier Transform Mass Spectrometry for the Analysis of Biomolecules
Author: Steven Travis FanninPublisher:
ISBN:
Category :
Languages : en
Pages : 312
Book Description
Application of Fourier Transform Mass Spectrometry to H/D Exchange of Biomolecules and Analysis of Porphyrins by Matrix-assisted Laser Desorption
Author: Melvin Kirk GreenMass Spectrometry for Biotechnology
Author: Gary SiuzdakPublisher: Elsevier
ISBN: 0080535844
Category : Science
Languages : en
Pages : 179
Book Description
If you investigate biological systems and might use mass spectrometry in your research but need to know more about it, this book is for you. It introduces the fundamental concepts of mass spectrometry and how mass spectrometers work. It also presents recent advancements particularly interesting to bio-researchers in an easy-to-understand manner that does not require extensive background in chemistry, math, or physics. Glossary of basic terms Abundant illustrations Examples of applications Practical tips on using mass spectrometric techniques Useful for peptide, protein, oligonucleotide, and carbohydrate analysis Simplified description of mass spectrometry including: Matrix-Assisted Laser Desorption/Ionization (MALDI) Electrospray Ionization (ESI) Fast Atom/Ion Bombardment (FAB)
Mass Spectrometry in the Biological Sciences: A Tutorial
Author: M.L GrossPublisher: Springer Science & Business Media
ISBN: 9401126186
Category : Science
Languages : en
Pages : 462
Book Description
The developments in mass spectrometry over the past fifteen years have been impressive in their implications in bioanalytical chemistry. The achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhanced the capabilities for ion trapping especially in analytical mass spectrometry. A major achievement was the development by Barber of Fast Atom Bombardment (FAB) mass spectrometry, an advance that heralded a new era in biological mass spectrometry. Contemporary and routine instruments such as magnetic sectors and quadrupoles were rapidly adapted to F AB, and nearly the entire universe of small molecules became amenable to study by mass spectrometry. The introduction of FAB also paved the way for improvement of instrument capability. For example, the upper mass limit of magnet sector mass spectrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was given new meaning because important structural information for biomolecules could now be produced for ions introduced by FAB into the tandem instrument. The evolution of MS/MS continues today with the development of ion traps, time-of-flight, and sector instruments equipped with array detection.
Analysis of Biomolecules Using Matrix-assisted Laser Desorption/ionization Mass Spectrometry
Author: Jennifer Ann FirestinePublisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 224
Book Description
Developments in Matrix-assisted Laser Desorption/ionization (MALDI) Fourier Transform Mass Spectrometry
Author: Jie YaoPublisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 314
Book Description
Application of Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry to the Study of Bacterial Biomolecules
Author: Teresa Catherine CainPublisher:
ISBN:
Category :
Languages : en
Pages : 234
Book Description
Applications of Matrix Assisted Laser Desorption/ionization Fourier Transform Mass Spectrometry for Phospholipid Analysis
Author: S. Mariccor Andresa Banluta BatoyPublisher:
ISBN:
Category : Fourier transform spectroscopy
Languages : en
Pages : 314
Book Description
Electrospray and MALDI Mass Spectrometry
Author: Richard B. ColePublisher: John Wiley & Sons
ISBN: 1118211553
Category : Science
Languages : en
Pages : 900
Book Description
Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.