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An Outline of Informational Genetics

An Outline of Informational Genetics PDF Author: Gerard Battail
Publisher: Springer Nature
ISBN: 3031016297
Category : Technology & Engineering
Languages : en
Pages : 191

Book Description
Heredity performs literal communication of immensely long genomes through immensely long time intervals. Genomes nevertheless incur sporadic errors referred to as mutations which have significant and often dramatic effects, after a time interval as short as a human life. How can faithfulness at a very large timescale and unfaithfulness at a very short one be conciliated? The engineering problem of literal communication has been completely solved during the second half of the XX-th century. Originating in 1948 from Claude Shannon's seminal work, information theory provided means to measure information quantities and proved that communication is possible through an unreliable channel (by means left unspecified) up to a sharp limit referred to as its capacity, beyond which communication becomes impossible. The quest for engineering means of reliable communication, named error-correcting codes, did not succeed in closely approaching capacity until 1993 when Claude Berrou and Alain Glavieux invented turbocodes. By now, the electronic devices which invaded our daily lives (e.g., CD, DVD, mobile phone, digital television) could not work without highly efficient error-correcting codes. Reliable communication through unreliable channels up to the limit of what is theoretically possible has become a practical reality: an outstanding achievement, however little publicized. As an engineering problem that nature solved aeons ago, heredity is relevant to information theory. The capacity of DNA is easily shown to vanish exponentially fast, which entails that error-correcting codes must be used to regenerate genomes so as to faithfully transmit the hereditary message. Moreover, assuming that such codes exist explains basic and conspicuous features of the living world, e.g., the existence of discrete species and their hierarchical taxonomy, the necessity of successive generations and even the trend of evolution towards increasingly complex beings. Providing geneticists with an introduction to information theory and error-correcting codes as necessary tools of hereditary communication is the primary goal of this book. Some biological consequences of their use are also discussed, and guesses about hypothesized genomic codes are presented. Another goal is prompting communication engineers to get interested in genetics and biology, thereby broadening their horizon far beyond the technological field, and learning from the most outstanding engineer: Nature. Table of Contents: Foreword / Introduction / A Brief Overview of Molecular Genetics / An Overview of Information Theory / More on Molecular Genetics / More on Information Theory / An Outline of Error-Correcting Codes / DNA is an Ephemeral Memory / A Toy Living World / Subsidiary Hypothesis, Nested System / Soft Codes / Biological Reality Conforms to the Hypotheses / Identification of Genomic Codes / Conclusion and Perspectives

An Outline of Informational Genetics

An Outline of Informational Genetics PDF Author: Gerard Battail
Publisher: Springer Nature
ISBN: 3031016297
Category : Technology & Engineering
Languages : en
Pages : 191

Book Description
Heredity performs literal communication of immensely long genomes through immensely long time intervals. Genomes nevertheless incur sporadic errors referred to as mutations which have significant and often dramatic effects, after a time interval as short as a human life. How can faithfulness at a very large timescale and unfaithfulness at a very short one be conciliated? The engineering problem of literal communication has been completely solved during the second half of the XX-th century. Originating in 1948 from Claude Shannon's seminal work, information theory provided means to measure information quantities and proved that communication is possible through an unreliable channel (by means left unspecified) up to a sharp limit referred to as its capacity, beyond which communication becomes impossible. The quest for engineering means of reliable communication, named error-correcting codes, did not succeed in closely approaching capacity until 1993 when Claude Berrou and Alain Glavieux invented turbocodes. By now, the electronic devices which invaded our daily lives (e.g., CD, DVD, mobile phone, digital television) could not work without highly efficient error-correcting codes. Reliable communication through unreliable channels up to the limit of what is theoretically possible has become a practical reality: an outstanding achievement, however little publicized. As an engineering problem that nature solved aeons ago, heredity is relevant to information theory. The capacity of DNA is easily shown to vanish exponentially fast, which entails that error-correcting codes must be used to regenerate genomes so as to faithfully transmit the hereditary message. Moreover, assuming that such codes exist explains basic and conspicuous features of the living world, e.g., the existence of discrete species and their hierarchical taxonomy, the necessity of successive generations and even the trend of evolution towards increasingly complex beings. Providing geneticists with an introduction to information theory and error-correcting codes as necessary tools of hereditary communication is the primary goal of this book. Some biological consequences of their use are also discussed, and guesses about hypothesized genomic codes are presented. Another goal is prompting communication engineers to get interested in genetics and biology, thereby broadening their horizon far beyond the technological field, and learning from the most outstanding engineer: Nature. Table of Contents: Foreword / Introduction / A Brief Overview of Molecular Genetics / An Overview of Information Theory / More on Molecular Genetics / More on Information Theory / An Outline of Error-Correcting Codes / DNA is an Ephemeral Memory / A Toy Living World / Subsidiary Hypothesis, Nested System / Soft Codes / Biological Reality Conforms to the Hypotheses / Identification of Genomic Codes / Conclusion and Perspectives

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

Book Description


Schaum's Outline of Theory and Problems of Genetics

Schaum's Outline of Theory and Problems of Genetics PDF Author: Susan L. Elrod
Publisher: Schaum's Outline Series
ISBN:
Category : Genetics
Languages : en
Pages : 514

Book Description
Tough Test Questions? Missed Lectures? Not Enough Time? Fortunately for you, there's Schaum's Outlines. More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test your skills. This Schaum's Outline gives you Practice problems with full explanations that reinforce knowledge Coverage of the most up-to-date developments in your course field In-depth review of practices and applications Fully compatible with your classroom text, Schaum's highlights all the important facts you need to know. Use Schaum's to shorten your study time-and get your best test scores! Schaum's Outlines-Problem Solved.

The Nucleolus

The Nucleolus PDF Author: Mark O. J. Olson
Publisher: Springer Science & Business Media
ISBN: 1461405149
Category : Science
Languages : en
Pages : 434

Book Description
Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.

Genetic Entropy

Genetic Entropy PDF Author: John C. Sanford
Publisher:
ISBN: 9780981631608
Category : Nature
Languages : en
Pages : 0

Book Description
In this text, Sanford, a retired Cornell professor, shows that the "Primary Axiom"--the foundational evolutionary premise that life is merely the result of mutations and natural selection--is false. He strongly refutes the Darwinian concept that man is just the result of a random and pointless natural process.

Information and Life

Information and Life PDF Author: Gérard Battail
Publisher: Springer Science & Business Media
ISBN: 9400770405
Category : Science
Languages : en
Pages : 264

Book Description
Communication, one of the most important functions of life, occurs at any spatial scale from the molecular one up to that of populations and ecosystems, and any time scale from that of fast chemical reactions up to that of geological ages. Information theory, a mathematical science of communication initiated by Shannon in 1948, has been very successful in engineering, but biologists ignore it. This book aims at bridging this gap. It proposes an abstract definition of information based on the engineers' experience which makes it usable in life sciences. It expounds information theory and error-correcting codes, its by-products, as simply as possible. Then, the fundamental biological problem of heredity is examined. It is shown that biology does not adequately account for the conservation of genomes during geological ages, which can be understood only if it is assumed that genomes are made resilient to casual errors by proper coding. Moreover, the good conservation of very old parts of genomes, like the HOX genes, implies that the assumed genomic codes have a nested structure which makes an information the more resilient to errors, the older it is. The consequences that information theory draws from these hypotheses meet very basic but yet unexplained biological facts, e.g., the existence of successive generations, that of discrete species and the trend of evolution towards complexity. Being necessarily inscribed on physical media, information appears as a bridge between the abstract and the concrete. Recording, communicating and using information exclusively occur in the living world. Information is thus coextensive with life and delineates the border between the living and the inanimate.

Basic Genetics

Basic Genetics PDF Author: Ahmed Abouelmagd
Publisher: Universal-Publishers
ISBN: 1612331920
Category : Science
Languages : en
Pages : 292

Book Description
Basic Genetics is a concise introductory textbook that focuses not only on understanding and explaining the main points of genetics, but also upon covering the required essential traditional subjects in the field. The main goal of this textbook is to help first year students who are taking their first course in human genetics to understand the different topics within genetics. It is of particular interest for those who are preparing themselves to study medicine or other medical sciences. This textbook presents only the essential required information. Some of the different subjects included in the eight chapters are: cell cycle and cellular division, Mendelian principles of heredity, the molecular basis of genetic material, gene expression and gene expression control, genetic variations and genetic engineering, as well as human genetics. In addition, Basic Genetics contains multiple choice questions covering each topic and their answers. These questions are absolutely essential for students' self- assessment. These different topics of basic genetics have also been illustrated by simple diagrams in full color.

A Brief History of Genetics

A Brief History of Genetics PDF Author: Chris Rider
Publisher: Cambridge Scholars Publishing
ISBN: 1527561305
Category : Science
Languages : en
Pages : 514

Book Description
Biological inheritance, the passage of key characteristics down the generations, has always held mankind’s fascination. It is fundamental to the breeding of plants and animals with desirable traits. Genetics, the scientific study of inheritance, can be traced back to a particular set of simple but ground-breaking studies carried out 170 years ago. The awareness that numerous diseases are inherited gives this subject considerable medical importance. The progressive advances in genetics now bring us to the point where we have unravelled the entire human genome, and that of many other species. We can intervene very precisely with the genetic make-up of our agricultural crops and animals, and even ourselves. Genetics now enables us to understand cancer and develop novel protein medicines. It has also provided us with DNA fingerprinting for the solving of serious crime. This book explains for a lay readership how, where and when this powerful science emerged.

Schaum's Outline of Genetics, Fifth Edition

Schaum's Outline of Genetics, Fifth Edition PDF Author: Susan Elrod
Publisher: McGraw Hill Professional
ISBN: 0071625046
Category : Study Aids
Languages : en
Pages : 426

Book Description
Tough Test Questions? Missed Lectures? Not Enough Time? Fortunately for you, there's Schaum's. More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solvedproblems, and practice exercises to test your skills. This Schaum's Outline gives you 450 fully solved problems Complete review of all course fundamentals Hundreds of examples with explanations of genetics concepts Exercises to help you test your mastery of genetics Fully compatible with your classroom text, Schaum's highlights all the important facts you need to know. Use Schaum's to shorten your study time--and get your best test scores! Topics include: The Physical Basis of Heredity; Patterns of Inheritance; The Biochemical Casis of Heredity; Genetic Interactions; The Genetics of Sex; Linkage and Chromosome Mapping; Cytogenetics; Quantitative Genetics; Population Genetics and Evolution; Genetics of Bacteria; Viruses, Transposable Elements, and Cancer; Molecular Genetics and Biotechnology; and The Molecular Biology of Eukaryotes Schaum's Outlines--Problem Solved.

A History of Genetics

A History of Genetics PDF Author: Alfred Henry Sturtevant
Publisher: CSHL Press
ISBN: 9780879696078
Category : Medical
Languages : en
Pages : 190

Book Description
In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.