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Author: A. G. Fishburn Publisher: Elsevier ISBN: 1483138534 Category : Medical Languages : en Pages : 201
Book Description
An Introduction to Pharmaceutical Formulation describes the various forms in which drugs may be supplied to doctors, patients, and veterinary surgeons. An account is given of the materials which may be added to drugs in order to provide formulated products, and of the methods by which formulations are assessed. The book begins with a background on pharmaceutical formulation, describing manufactured and official formulations, important criteria for a formulation, and technical advances in pharmacy during the post-war period. This is followed by separate chapters on diluents, solvents, and liquid vehicles; thickeners and binders; the chemistry and pharmacology of surface-active agents; and colors, flavors, and preservatives. Subsequent chapters cover solid, liquid, and paste formulations; controlled drug release; the stability of formulations; the importance of the container of the formulation; and large-scale manufacturing of formulated products. This book is intended primarily for students of pharmacy. It is not a textbook of practical or theoretical pharmaceutics but should be read in conjunction with other books on these subjects.
Author: A. G. Fishburn Publisher: Elsevier ISBN: 1483138534 Category : Medical Languages : en Pages : 201
Book Description
An Introduction to Pharmaceutical Formulation describes the various forms in which drugs may be supplied to doctors, patients, and veterinary surgeons. An account is given of the materials which may be added to drugs in order to provide formulated products, and of the methods by which formulations are assessed. The book begins with a background on pharmaceutical formulation, describing manufactured and official formulations, important criteria for a formulation, and technical advances in pharmacy during the post-war period. This is followed by separate chapters on diluents, solvents, and liquid vehicles; thickeners and binders; the chemistry and pharmacology of surface-active agents; and colors, flavors, and preservatives. Subsequent chapters cover solid, liquid, and paste formulations; controlled drug release; the stability of formulations; the importance of the container of the formulation; and large-scale manufacturing of formulated products. This book is intended primarily for students of pharmacy. It is not a textbook of practical or theoretical pharmaceutics but should be read in conjunction with other books on these subjects.
Author: Geoffrey D Tovey Publisher: Royal Society of Chemistry ISBN: 1849739412 Category : Science Languages : en Pages : 432
Book Description
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
Author: Jiben Roy Publisher: Elsevier ISBN: 1908818042 Category : Medical Languages : en Pages : 449
Book Description
This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processes Covers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries
Author: Geoffrey D Tovey Publisher: Royal Society of Chemistry ISBN: 178801443X Category : Science Languages : en Pages : 432
Book Description
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
Author: Alexander Taylor Florence Publisher: Pharmaceutical Press ISBN: 0853696918 Category : Medical Languages : en Pages : 198
Book Description
This textbook describes a variety of dosage forms and their clinical importance and use. The use and behaviour of dosage forms in different age groups and patient groups will also be considered along with recent developments such as personalised therapies and genomics. It contains relevant examples and clinical case studies.
Author: Simon Gaisford Publisher: John Wiley & Sons ISBN: 1118423240 Category : Science Languages : en Pages : 234
Book Description
Essentials of Pharmaceutical Preformulation is a study guide which describes the basic principles of pharmaceutical physicochemical characterisation. Successful preformulation requires knowledge of fundamental molecular concepts (solubility, ionisation, partitioning, hygroscopicity and stability) and macroscopic properties (physical form, such as the crystalline and amorphous states, hydrates, solvates and co-crystals and powder properties), familiarity with the techniques used to measure them and appreciation of their effect on product performance, recognising that often there is a position of compromise to be reached between product stability and bioavailability. This text introduces the basic concepts and discusses their wider implication for pharmaceutical development, with reference to many case examples of current drugs and drug products. Special attention is given to the principles and best-practice of the analytical techniques that underpin preformulation (UV spectrophotometry, TLC, DSC, XRPD and HPLC). The material is presented in the typical order that would be followed when developing a medicine and maps onto the indicative pharmacy syllabus of the Royal Pharmaceutical Society of Great Britain Undergraduate-level pharmacy students and R&D / analytical scientists working in the pharmaceutical sector (with or without a pharmaceutical background) will find this text easy to follow with relevant pharmaceutical examples. Essential study guide for pharmacy and pharmaceutical science students Covers the pharmaceutical preformulation components of the Royal Pharmaceutical Society of Great Britain’s indicative syllabus Easy to follow text highlighted with relevant pharmaceutical examples Self-assessment assignments in a variety of formats Written by authors with both academic and industrial experience Companion website with further information to maximise learning
Author: Mark Gibson Publisher: CRC Press ISBN: 1420073184 Category : Medical Languages : en Pages : 562
Book Description
Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form reflects the mounting pressure on pharmaceutical companies to accelerate the new drug development and launch process, as well as the shift from developing small molecules to the growth of biopharmaceuticals. The book meets the ne
Author: Geoffrey D Tovey Publisher: Royal Society of Chemistry ISBN: 1839165618 Category : Science Languages : en Pages : 359
Book Description
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety, and stability of the final medicinal product. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Following on from Pharmaceutical Formulation, which covered traditional dosage forms such as tablets and capsules, this volume expands upon those formulations to cover a more diverse range of less common dosage forms. Novel routes of administration are covered from inhalational, dermal and transdermal formulations to ocular, oral suspensions, vaccines and nanoparticle drug delivery. The methods through which these formulations are processed and manufactured is also covered, providing essential knowledge to ensure quality, efficiency, and acceptable costing. Specialised Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry and will equip readers with the ability to effectively and reliably produce products which can be approved, manufactured and made available to administer to patients.
Author: Sarfaraz K. Niazi Publisher: CRC Press ISBN: 1351594907 Category : Medical Languages : en Pages : 769
Book Description
The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume One, Compressed Solid Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this first volume of a six-volume set, compiles data from FDA new drug applications, patent applications, and other sources of generic and proprietary formulations to cover the broad spectrum of GMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent.
Author: A. G. Fishburn
Author: A. G. Fishburn
Author: Geoffrey D Tovey
Author: Gordon John Weston
Author: Jiben Roy
Author: Geoffrey D Tovey
Author: Alexander Taylor Florence
Author: Simon Gaisford
Author: Mark Gibson
Author: Geoffrey D Tovey
Author: Sarfaraz K. Niazi