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Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309316324 Category : Medical Languages : en Pages : 236
Book Description
Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309316324 Category : Medical Languages : en Pages : 236
Book Description
Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
Author: Michael Z. Hauschild Publisher: Springer ISBN: 3319564757 Category : Technology & Engineering Languages : en Pages : 1215
Book Description
This book is a uniquely pedagogical while still comprehensive state-of-the-art description of LCA-methodology and its broad range of applications. The five parts of the book conveniently provide: I) the history and context of Life Cycle Assessment (LCA) with its central role as quantitative and scientifically-based tool supporting society’s transitioning towards a sustainable economy; II) all there is to know about LCA methodology illustrated by a red-thread example which evolves as the reader advances; III) a wealth of information on a broad range of LCA applications with dedicated chapters on policy development, prospective LCA, life cycle management, waste, energy, construction and building, nanotechnology, agrifood, transport, and LCA-related concepts such as footprinting, ecolabelling,design for environment, and cradle to cradle. IV) A cookbook giving the reader recipes for all the concrete actions needed to perform an LCA. V) An appendix with an LCA report template, a full example LCA report serving as inspiration for students who write their first LCA report, and a more detailed overview of existing LCIA methods and their similarities and differences.
Author: Robby Caspeele Publisher: CRC Press ISBN: 1351857576 Category : Technology & Engineering Languages : en Pages : 3160
Book Description
This volume contains the papers presented at IALCCE2018, the Sixth International Symposium on Life-Cycle Civil Engineering (IALCCE2018), held in Ghent, Belgium, October 28-31, 2018. It consists of a book of extended abstracts and a USB device with full papers including the Fazlur R. Khan lecture, 8 keynote lectures, and 390 technical papers from all over the world. Contributions relate to design, inspection, assessment, maintenance or optimization in the framework of life-cycle analysis of civil engineering structures and infrastructure systems. Life-cycle aspects that are developed and discussed range from structural safety and durability to sustainability, serviceability, robustness and resilience. Applications relate to buildings, bridges and viaducts, highways and runways, tunnels and underground structures, off-shore and marine structures, dams and hydraulic structures, prefabricated design, infrastructure systems, etc. During the IALCCE2018 conference a particular focus is put on the cross-fertilization between different sub-areas of expertise and the development of an overall vision for life-cycle analysis in civil engineering. The aim of the editors is to provide a valuable source of cutting edge information for anyone interested in life-cycle analysis and assessment in civil engineering, including researchers, practising engineers, consultants, contractors, decision makers and representatives from local authorities.
Author: Mary Ann Curran Publisher: John Wiley & Sons ISBN: 1118528271 Category : Technology & Engineering Languages : en Pages : 634
Book Description
The first book of its kind, the Life Cycle Assessment Handbook: A Guide for Environmentally Sustainable Products will become an invaluable resource for environmentally progressive manufacturers and suppliers, product and process designers, executives and managers, and government officials who want to learn about this essential component of environmental sustainability. As the last several decades have seen a dramatic rise in the application of Life Cycle Assessment (LCA) in decision making, the interest in the life cycle concept as an environmental management and sustainability tool continues to grow. The LCA Handbook offers a look at the role that life cycle information, in the hands of companies, governments, and consumers, may have in improving the environmental performance of products and technologies. It concisely and clearly presents the various aspects of LCA in order to help the reader better understand the subject. The content of the book was designed with a certain flow in mind. After a high-level overview to describe current views and state-of-the-practice of LCA, it presents chapters that address specific LCA methodological issues including creating life cycle inventory, life cycle impact assessment, and capturing eco-systems services. These are followed by example applications of LCA in the agri-food industry; sustainable supply chain management; solid waste management; mining and mineral extraction; forest products; buildings; product innovation; and sustainable chemistry and engineering. The international success of the sustainability paradigm needs the participation of many stakeholders, including citizens, corporations, academia, and NGOs. The handbook links LCA and responsible decision making and how the life cycle concept is a critical element in environmental sustainability. It covers issues such as building capacity in developing countries and emerging economies so that they are more capable of harnessing the potential in LCA for sustainable development. Governments play a very important role with the leverage they have through procurement, regulation, international treaties, tax incentives, public outreach, and other policy tools. This compilation points to the clear trend for incorporating life cycle information into the design and development processes for products and policies, just as quality and safety concerns are now addressed throughout product design and development.
Author: T. J. O'Neill Publisher: iSmithers Rapra Publishing ISBN: 9781859573648 Category : Business & Economics Languages : en Pages : 148
Book Description
This review describes the process of life cycle analysis in some detail. It describes the different organisations involved in researching and applying these techniques and the database resources being used to generate comparative reports. The overview explains the factors to be considered, the terminology, the organisations involved in developing these techniques and the legislation which is driving the whole process forward. The ISO standards relating to environmental management are also discussed briefly in the document. Design for the environment is covered in the report. This review is accompanied by summaries of selected papers on life cycle analysis and environmental impact from the Rapra Polymer Library database.
Author: National Research Council Publisher: National Academies Press ISBN: 0309174791 Category : Science Languages : en Pages : 142
Book Description
The United States produces 25% of the world's wood output, and wood supports a major segment of the U.S. industrial base. Trees provide fiber, resins, oils, pulp, food, paper, pharmaceuticals, fuel, many products used in home construction, and numerous other products. The use of wood as a raw material must consider production efficiencies and natural resource conservation as well as efficient, profitable use of solid wood, its residues, and by-products. To better assess the use of wood as a raw material, the U.S. Department of Agriculture's Forest Service asked the National Research Council's Board on Agriculture to bring together experts to review the analytical techniques used to follow the life-cycle of wood productionâ€"from tree to productâ€"and assess the environmental impacts. This resulting book provides a base of current knowledge, identifying what data are lacking, where future efforts should be focused, and what is known about the methodologies used to assess environmental impacts. The book also focuses on national and international efforts to develop integrated environmental, economic, and energy accounting methologies.
Author: Mary Ann Curran Publisher: John Wiley & Sons ISBN: 1119083559 Category : Technology & Engineering Languages : en Pages : 247
Book Description
This student version of the popular bestseller, Life Cycle Assessment Handbook, is not a watered-down version of the original, but retains all of the important information and valuable lessons provided in the first book, along with helpful problems and solutions for the student learning about Life Cycle Assessment (LCA). As the last several decades have seen a dramatic rise in the application of LCA in decision making, the interest in the life cycle concept as an environmental management and sustainability tool continues to grow. The LCA Student Handbook offers a look at the role that life cycle information, in the hands of companies, governments and consumers, may have in improving the environmental performance of products and technologies. It concisely and clearly presents the various aspects of LCA in order to help the reader better understand the subject. The international success of the sustainability paradigm needs the participation of many stakeholders, including citizens, corporations, academia, and NGOs. The handbook links LCA and responsible decision making and how the life cycle concept is a critical element in environmental sustainability. It covers issues such as building capacity in developing countries and emerging economies so that they are more capable of harnessing the potential in LCA for sustainable development. Governments play a very important role with the leverage they have through procurement, regulation, international treaties, tax incentives, public outreach, and other policy tools. This compilation of points to the clear trend for incorporating life cycle information into the design and development processes for products and policies, just as quality and safety concerns are now addressed throughout product design and development. The Life Cycle Assessment Student Handbook is not just for students. It is also a valuable resource for practitioners looking for a desktop reference on LCA or for any engineer, manager, or policy-maker wishing to learn about LCA.
Author: Subramanian Senthilkannan Muthu Publisher: Woodhead Publishing ISBN: 0081001878 Category : Technology & Engineering Languages : en Pages : 401
Book Description
Life cycle assessment (LCA) is used to evaluate the environmental impacts of textile products, from raw material extraction, through fibre processing, textile manufacture, distribution and use, to disposal or recycling. LCA is an important tool for the research and development process, product and process design, and labelling of textiles and clothing. Handbook of Life Cycle Assessment (LCA) of Textiles and Clothing systematically covers the LCA process with comprehensive examples and case studies. Part one of the book covers key indicators and processes in LCA, from carbon and ecological footprints to disposal, re-use and recycling. Part two then discusses a broad range of LCA applications in the textiles and clothing industry. - Covers the LCA process and its key indicators, including carbon and ecological footprints, disposal, re-use and recycling - Examines the key developments of LCA in the textile and clothing industries - Provides a wide range of case studies and examples of LCA applications in the textile and clothing industries
Author: Subramanian Senthilkannan Muthu Publisher: Springer ISBN: 9812872965 Category : Technology & Engineering Languages : en Pages : 257
Book Description
This book details the primary concepts of Social Life Cycle Assessment (S-LCA), integration of social aspects in product life cycles, quantification of social impacts in S-LCA, impact categorization in S-LCA, methodological aspects of S-LCA, and detailed case studies. As the societal implications of producing a product are coming to take on a new importance, the concept of Social Life Cycle Assessment has recently been developed and is becoming increasingly prominent. However, S-LCA is still in its infancy and its impact categories for many industrial segments are still under development.
Author: John Harvey Publisher: CRC Press ISBN: 1000201724 Category : Technology & Engineering Languages : en Pages : 557
Book Description
An increasing number of agencies, academic institutes, and governmental and industrial bodies are embracing the principles of sustainability in managing their activities. Life Cycle Assessment (LCA) is an approach developed to provide decision support regarding the environmental impact of industrial processes and products. LCA is a field with ongoing research, development and improvement and is being implemented world-wide, particularly in the areas of pavement, roadways and bridges. Pavement, Roadway, and Bridge Life Cycle Assessment 2020 contains the contributions to the International Symposium on Pavement, Roadway, and Bridge Life Cycle Assessment 2020 (Davis, CA, USA, June 3-6, 2020) covering research and practical issues related to pavement, roadway and bridge LCA, including data and tools, asset management, environmental product declarations, procurement, planning, vehicle interaction, and impact of materials, structure, and construction. Pavement, Roadway, and Bridge Life Cycle Assessment 2020 will be of interest to researchers, professionals, and policymakers in academia, industry, and government who are interested in the sustainability of pavements, roadways and bridges.
Author: Institute of Medicine
Author: Institute of Medicine
Author: Michael Z. Hauschild
Author: Robby Caspeele
Author: Mary Ann Curran
Author: T. J. O'Neill
Author: National Research Council
Author: Mary Ann Curran
Author: Subramanian Senthilkannan Muthu
Author: Subramanian Senthilkannan Muthu
Author: John Harvey