Author: Douglas Mackenzie Scott
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Amino Acid Transport in Cultured Mammalian Cells
Mammalian Amino Acid Transport
Author: D. Häussinger
Publisher: Springer Science & Business Media
ISBN: 1489911618
Category : Science
Languages : en
Pages : 316
Book Description
Amino acid transport is a part of each of two larger subjects, amino acid metabolism and the biomembrane transport of various . small molecules and ions. Nevertheless in this volume we treat amino acid transport as more than a fragment of either of these two larger subjects. A more comprehensive approach is justified when we remember two historic and ongoing aspects of the title subject. First, amino acid transport had its beginning and acquired a distinct momentum (even if somewhat interrupted from 1913 until about 1945) as amino acid metabolism with the central and pioneer work of Van Slyke and Meyer in 1913. The reviews in this volume will show that it steadily becomes a larger aspect of amino acid metabolism, broadly perceived. These chapters will show for how many organelles, cells, tissues, organs and organ systems, the transmembrane compartmentations and flows of amino acids play very large parts in their fundamental biological relations. The authors here are tending collectively to evaluate an understanding of amino acid flows across biomernbranes, and the regulation of these flows, as necessary to an ultimate understanding of the full range of development and metabolism. Such an understanding goes far beyond the purely substrate-destabilizing contributions by enzymes, which have often been arbitrarily limited to that conceptual entity, "the cell", and which for so long a splendid time had most of biochemical research attention.
Publisher: Springer Science & Business Media
ISBN: 1489911618
Category : Science
Languages : en
Pages : 316
Book Description
Amino acid transport is a part of each of two larger subjects, amino acid metabolism and the biomembrane transport of various . small molecules and ions. Nevertheless in this volume we treat amino acid transport as more than a fragment of either of these two larger subjects. A more comprehensive approach is justified when we remember two historic and ongoing aspects of the title subject. First, amino acid transport had its beginning and acquired a distinct momentum (even if somewhat interrupted from 1913 until about 1945) as amino acid metabolism with the central and pioneer work of Van Slyke and Meyer in 1913. The reviews in this volume will show that it steadily becomes a larger aspect of amino acid metabolism, broadly perceived. These chapters will show for how many organelles, cells, tissues, organs and organ systems, the transmembrane compartmentations and flows of amino acids play very large parts in their fundamental biological relations. The authors here are tending collectively to evaluate an understanding of amino acid flows across biomernbranes, and the regulation of these flows, as necessary to an ultimate understanding of the full range of development and metabolism. Such an understanding goes far beyond the purely substrate-destabilizing contributions by enzymes, which have often been arbitrarily limited to that conceptual entity, "the cell", and which for so long a splendid time had most of biochemical research attention.
THE TRANSPORT OF CATIONIC AMINO ACIDS ACROSS THE PLASMA MEMBRANE OF CULTURED MAMMALIAN CELLS.
Author: MORRIS FRANCIS WHITE (JR.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 295
Book Description
half-maximally saturates efflux. The maximum flux attained by raising the substrate concentration is equal in both directions. These kinetic relations are consistent with the observed 5- to 20-fold accumulation of cationic amino acids into fibroblasts and HTC cells.
Publisher:
ISBN:
Category :
Languages : en
Pages : 295
Book Description
half-maximally saturates efflux. The maximum flux attained by raising the substrate concentration is equal in both directions. These kinetic relations are consistent with the observed 5- to 20-fold accumulation of cationic amino acids into fibroblasts and HTC cells.
Mechanism of Amino Acid Transport in Mammalian Cells
Author: Alma Domjan Melbourne
Publisher:
ISBN:
Category :
Languages : en
Pages : 284
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 284
Book Description
Amino Acid Transport in Mammalian Tissues
Author: Armando Roberto Tovar
Publisher:
ISBN:
Category :
Languages : en
Pages : 514
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 514
Book Description
Transport
Author: Edward D. Korn
Publisher: Springer Science & Business Media
ISBN: 1468469762
Category : Science
Languages : en
Pages : 212
Book Description
One property common to all cells is transport. Molecules and ions must enter and leave cells by crossing membranes in a controlled manner. The process may take any of several forms: simple diffusion, carrier-mediated diffusion, active transport, or group translocation. There is more than one way to measure each. Transport kinetics, with particular reference to the red blood cell, were discussed in a previous volume. Three chapters deal with the general subject of transport in this volume. Maloney, Kashket, and Wilson summarize the appropriate methodology for studying metabolite and ion transport in bacteria, and Kimmich describes the relevant method ology for the isolated intestinal epithelial cell. The methods described in these two chapters have general application to transport studies in single cells from any source. The approach described in these two complementary articles is extended in the chapter by Hochstadt and her collaborators on the use of isolated membranes from bacterial and mammalian cells for the study of trans port phenomena. If one can prepare a suitable plasma membrane fraction (sealed, impermeable vesicles with the necessary transport components intact), it becomes possible to separate the events of transport from any subsequent metabolism that may occur in the cell. Isolated membrane vesicles are relatively easy to obtain from bacteria, and they are com paratively well studied. Work with similar preparations from cultured mammalian cells is just beginning but has much promise.
Publisher: Springer Science & Business Media
ISBN: 1468469762
Category : Science
Languages : en
Pages : 212
Book Description
One property common to all cells is transport. Molecules and ions must enter and leave cells by crossing membranes in a controlled manner. The process may take any of several forms: simple diffusion, carrier-mediated diffusion, active transport, or group translocation. There is more than one way to measure each. Transport kinetics, with particular reference to the red blood cell, were discussed in a previous volume. Three chapters deal with the general subject of transport in this volume. Maloney, Kashket, and Wilson summarize the appropriate methodology for studying metabolite and ion transport in bacteria, and Kimmich describes the relevant method ology for the isolated intestinal epithelial cell. The methods described in these two chapters have general application to transport studies in single cells from any source. The approach described in these two complementary articles is extended in the chapter by Hochstadt and her collaborators on the use of isolated membranes from bacterial and mammalian cells for the study of trans port phenomena. If one can prepare a suitable plasma membrane fraction (sealed, impermeable vesicles with the necessary transport components intact), it becomes possible to separate the events of transport from any subsequent metabolism that may occur in the cell. Isolated membrane vesicles are relatively easy to obtain from bacteria, and they are com paratively well studied. Work with similar preparations from cultured mammalian cells is just beginning but has much promise.
Amino Acid Interactions in Intracellular Pool Formation and Protein Synthesis in Cultured Mammalian Cells
Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
Book Description
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
Book Description
The Placenta and Human Developmental Programming
Author: Graham J. Burton
Publisher: Cambridge University Press
ISBN: 1139494228
Category : Medical
Languages : en
Pages : 267
Book Description
Developmental programming is a rapidly advancing discipline of great importance to basic scientists and health professionals alike. This text integrates, for the first time, contributions from world experts to explore the role of the placenta in developmental programming. The book considers the materno-fetal supply line, and how perturbations of placental development impact on its functional capacity. Chapters examine ways in which environmental, immunological and vascular insults regulate expression of conventional and imprinted genes, along with their impact on placental shape and size, transport, metabolism and endocrine function. Research in animal models is integrated with human clinical and epidemiological data, and questions for future research are identified. Transcripts of discussions between the authors allow readers to engage with controversial issues. Essential reading for researchers in placental biology and developmental programming, as well as specialists and trainees in the wider field of reproductive medicine.
Publisher: Cambridge University Press
ISBN: 1139494228
Category : Medical
Languages : en
Pages : 267
Book Description
Developmental programming is a rapidly advancing discipline of great importance to basic scientists and health professionals alike. This text integrates, for the first time, contributions from world experts to explore the role of the placenta in developmental programming. The book considers the materno-fetal supply line, and how perturbations of placental development impact on its functional capacity. Chapters examine ways in which environmental, immunological and vascular insults regulate expression of conventional and imprinted genes, along with their impact on placental shape and size, transport, metabolism and endocrine function. Research in animal models is integrated with human clinical and epidemiological data, and questions for future research are identified. Transcripts of discussions between the authors allow readers to engage with controversial issues. Essential reading for researchers in placental biology and developmental programming, as well as specialists and trainees in the wider field of reproductive medicine.
Amino Acid Transport in Cultured 3T3 Cells
Author: Kathryn Cooper
Publisher:
ISBN:
Category : Amino acids
Languages : en
Pages : 102
Book Description
Publisher:
ISBN:
Category : Amino acids
Languages : en
Pages : 102
Book Description