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Aggregation Functions

Aggregation Functions PDF Author: Michel Grabisch
Publisher: Cambridge University Press
ISBN: 0521519268
Category : Computers
Languages : en
Pages : 481

Book Description
A rigorous and self-contained exposition of aggregation functions and their properties.

Aggregation Functions

Aggregation Functions PDF Author: Michel Grabisch
Publisher: Cambridge University Press
ISBN: 0521519268
Category : Computers
Languages : en
Pages : 481

Book Description
A rigorous and self-contained exposition of aggregation functions and their properties.

Aggregation of Therapeutic Proteins

Aggregation of Therapeutic Proteins PDF Author: Wei Wang
Publisher: John Wiley & Sons
ISBN: 1118043588
Category : Medical
Languages : en
Pages : 400

Book Description
This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.

Microbial Aggregation

Microbial Aggregation PDF Author: Calleja
Publisher: CRC Press
ISBN: 1351082973
Category : Science
Languages : en
Pages : 282

Book Description
This text covers in detail bacteria and yeasts, including an overall perspective of microbial aggregation as fundamental form and function, which is presented here to include systems still to be treated in detail.

Matter Aggregation

Matter Aggregation PDF Author: Philip F. Yuan
Publisher: Oro Editions
ISBN: 9781951541750
Category : Architecture
Languages : en
Pages : 180

Book Description
Within the human-machine collaborations cultivated in the digital age, crafts and materials are playing an increasingly important role in forming various ways of matter aggregation for architecture. Based on the pedagogical exploration of the design studio--Matter Aggregation at UVA, the book seeks new values of wood craft for contemporary architectural design, by introducing digital design and robotic fabrication techniques into the design process for timber building. The book integrates explorations of traditional crafts with digital fabrication technique, establishing a digital crafting as a new field for contemporary practice. The book explores the computational mechanisms and diagrammatic grammar within these craft-based aggregation systems, paying close attention to geometrical configurations, material effects and fabrication details and take advantage of these qualities to produce a unique spatiality.

Protein Misfolding, Aggregation and Conformational Diseases

Protein Misfolding, Aggregation and Conformational Diseases PDF Author: Vladimir N. Uversky
Publisher: Springer Science & Business Media
ISBN: 0387259198
Category : Science
Languages : en
Pages : 450

Book Description
Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. This is the first book to discuss significant achievements in protein structure-function relationships in biochemistry, molecular biology and molecular medicine. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.

Red Blood Cell Aggregation

Red Blood Cell Aggregation PDF Author: Oguz Baskurt
Publisher: CRC Press
ISBN: 1439841802
Category : Medical
Languages : en
Pages : 326

Book Description
Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.

Aggregation Operators

Aggregation Operators PDF Author: Tomasa Calvo
Publisher: Springer Science & Business Media
ISBN: 9783790814682
Category : Computers
Languages : en
Pages : 376

Book Description
1. The increasing number of research papers appeared in the last years that either make use of aggregation functions or contribute to its theoretieal study asses its growing importance in the field of Fuzzy Logie and in others where uncertainty and imprecision play a relevant role. Since these papers are pub lished in many journals, few books and several proceedings of conferences, books on aggregation are partieularly welcome. To my knowledge, "Agrega tion Operators. New Trends and Applications" is the first book aiming at generality , and I take it as a honour to write this Foreword in response to the gentle demand of its editors, Radko Mesiar, Tomasa Calvo and Gaspar Mayor. My pleasure also derives from the fact that twenty years aga I was one of the first Spaniards interested in the study of aggregation functions, and this book includes work by several Spanish authors. The book contains nice and relevant original papers, authored by some of the most outstanding researchers in the field, and since it can serve, as the editors point out in the Preface, as a small handbook on aggregation, the book is very useful for those entering the subject for the first time. The book also contains apart dealing with potential areas of application, so it can be helpful in gaining insight on the future developments.

Reef Fish Spawning Aggregations: Biology, Research and Management

Reef Fish Spawning Aggregations: Biology, Research and Management PDF Author: Yvonne Sadovy de Mitcheson
Publisher: Springer Science & Business Media
ISBN: 9400719809
Category : Science
Languages : en
Pages : 639

Book Description
Reef fish spawning aggregations, ranging from small groups to many tens of thousands of individuals, are spectacular but poorly known natural phenomena whereby fish assemble at specific times and locations to spawn. For some species these large groups may be the only form of reproduction, the high fish numbers briefly giving a false impression of stability and abundance—an ‘illusion of plenty’. They are often a focus for intensive seasonal fishing because of their predictability and because many important commercial fishes form them. Highly vulnerable to overexploitation, many aggregations and their associated fisheries, have disappeared or are in decline. Few are effectively managed or incorporated into protected areas. Aggregations are not well understood by fishery scientists, managers and conservationists and their significance little appreciated by fishers or the wider public. To ensure their persistence to replenish important fisheries in coral ecosystems, maintain their ecosystem function and continue to delight divers, a significant change in perspective is needed to foster protection and management. This book provides comprehensive and practical coverage of the biology, study and management of reef fish aggregations, exploring their how, when, where, and why. It explores ways to better protect, study, manage and conserve them, while identifying key data gaps and questions. The text is extensively illustrated with many unique, never before published, photographs and graphics. Case studies on over 20 interesting and important fishes are included, outlining their biology and fisheries and highlighting major concerns and challenges.

Analysis of Aggregates and Particles in Protein Pharmaceuticals

Analysis of Aggregates and Particles in Protein Pharmaceuticals PDF Author: Hanns-Christian Mahler
Publisher: John Wiley & Sons
ISBN: 0470497181
Category : Medical
Languages : en
Pages : 480

Book Description
This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.

Amyloid, Prions, and Other Protein Aggregates

Amyloid, Prions, and Other Protein Aggregates PDF Author:
Publisher: Elsevier
ISBN: 0080496679
Category : Science
Languages : en
Pages : 861

Book Description
This volume includes a core of methodologies to attack the unique experimental problems presented by protein misassembly. Emphasis is on human biology applications, the area in which there is the most interest, in which most of the work has already been done, and in which there is the best evidence for the structural sophisitication of the protein aggregates.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.