Advances in Viral Hepatitis B and D: Moving Toward the Goals of Elimination., An Issue of Clinics in Liver Disease PDF Download

Author: Robert G. Gish
Publisher: Elsevier Health Sciences
ISBN: 0323939481
Category : Medical
Languages : en
Pages : 257

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Book Description
In this issue of Clinics in Liver Disease, guest editor Robert G. Gish brings his considerable expertise to the topic of Hepatitis B and Hepatitis D. The articles provide state-of-the-art clinical summaries of the advances in Hepatitis B and D, with emphasis on HBV viro-immunology, novel assays, new targets, and tests for HBV and HDV, and more. Contains 13 relevant, practice-oriented topics including Novel Assays to Solve the Clinical and Scientific Challenges of Chronic Hepatitis B; Maternal-to-Child Transmission of Hepatitis B Virus and Hepatitis Delta Virus; Triple Threat: HDV, HBV, HIV Coinfection; Targeting Hepatitis B Virus DNA Using Designer Gene Editors; and more. Provides in-depth clinical reviews on Hepatitis B and D, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: Robert G. Gish
Publisher: Elsevier
ISBN: 9780323939478
Category : Medical
Languages : en
Pages : 0

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Author: David Bernstein
Publisher: Elsevier Health Sciences
ISBN: 044312146X
Category : Medical
Languages : en
Pages : 225

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Book Description
In this issue of Clinics in Liver Disease, guest editor Dr. David E. Bernstein brings his considerable expertise to the topic of Autoimmune Hepatitis Including PBC and PSC. The three main immune disorders that involve the liver are AIH, primary biliary cholangitis, and primary sclerosing cholangitis. As these autoimmune diseases can share symptoms, it is important for the hepatologist to have clinical knowledge of each and understand their differences and similarities. This issue addresses these variants and provides the reader with important information relating to pathology, diagnosis, and treatment. Contains 15 relevant, practice-oriented topics including autoimmune hepatitis: epidemiology, subtypes, and presentation; diagnosis of autoimmune hepatitis; treatment of autoimmune hepatitis including transplant; diagnostic tests in primary sclerosing cholangitis: serology, elastography, imaging; post-transplant management and complications of AIH, PBC, and PSC, including disease recurrence; and more. Provides in-depth clinical reviews on autoimmune hepatitis, including PBC and PSC, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: Sammy Saab
Publisher: Elsevier Health Sciences
ISBN: 0443121427
Category : Medical
Languages : en
Pages : 177

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In this issue of Clinics in Liver Disease, guest editor Dr. Sammy Saab brings his considerable expertise to the topic of Hepatic Encephalopathy. Hepatic encephalopathy (HE) is a reversible syndrome in patients with advanced liver dysfunction, and is characterized by a wide spectrum of neuropsychiatric abnormalities resulting from the accumulation of neurotoxic substances in the brain. In this issue, top experts provide detailed clinical reviews devoted to the epidemiology, manifestations, and management of HE in the hopes of improving patient outcomes. Contains 13 relevant, practice-oriented topics including clinical manifestations of HE; laboratory abnormalities of HE; pharmacologic management of HE; nontraditional treatment of HE; social impact of HE; future therapies of HE; and more. Provides in-depth clinical reviews on hepatic encephalopathy, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309438020
Category : Medical
Languages : en
Pages : 187

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Book Description
Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Author: Mitchell L Shiffman
Publisher: Elsevier Health Sciences
ISBN: 0323810691
Category : Medical
Languages : en
Pages : 249

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Book Description
In this issue of Clinics in Liver Disease, guest editor Mitchell L Shiffman brings considerable expertise to the topic of Challenging Issues in the Management of Chronic Hepatitis B Virus. Provides in-depth, clinical reviews on the latest updates in Challenging Issues in the Management of Chronic Hepatitis B Virus, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Author: Graham R. Foster
Publisher: John Wiley & Sons
ISBN: 1119533449
Category : Medical
Languages : en
Pages : 507

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Book Description
Das einzige evidenzbasierte Fachbuch zu viralen Lebererkrankungen, das sich ausschließlich mit schwierigen Situationen beschäftigt, mit denen sich klinische Hepatologen und das medizinische Personal immer wieder auseinandersetzen müssen. Auch wenn die virale Hepatitis weltweit auf dem Vormarsch ist und eine wachsende Bedrohung im Gesundheitswesen darstellt, ist für die Weltgesundheitsorganisation (WHO) die Ausrottung von Hepatitisinfektionen mittelfristig ein erreichbares Ziel. Wirksame Medikamente und Therapien stehen zwar zur Verfügung, das medizinische Personal, das Patienten mit viraler Hepatitis betreut, steht aber immer wieder vor der Herausforderung, in der heutigen medizinischen Literatur Antworten auf spezifische Fragen zu finden. Die 2. Auflage von Clinical Dilemmas in Viral Liver Disease ist ein evidenzbasierter Leitfaden für medizinisches Personal in den Bereichen Diagnose, Behandlung und Management von Patienten mit viralen Lebererkrankungen. Das komplett überarbeitete Referenzwerk zeigt neue Behandlungs- und Diagnoseansätze, die beitragen, die WHO-Ziele zu erreichen. Die einzelnen Kapitel untersuchen klar umrissene Themenfelder, gehen auf klinische Fragestellungen und Schwierigkeiten ein, vor denen Mediziner tagtäglich stehen. International renommierte Forscher und Kliniker beschäftigen sich in ihren Beiträgen mit klinischen Fragen und Problemen, die anderen Standardwerken und Online-Datensammlungen vielfach unberücksichtigt bleiben. Dieses einzigartige Fachbuch bietet praktische Hilfestellung zu den spezifischen Herausforderungen und Kernfragen bei der Behandlung von Patienten mit viralen Lebererkrankungen: - Bietet praxisorientierte, evidenzbasierte Hilfestellung zu aktuellen und kontroversen Themen. - Beschäftigt sich mit Fragestellungen, die im Klinikalltag auftreten und bislang wenig untersucht wurden. - Erörtert die Herausforderungen rund um globale Programme zur Ausrottung von Hepatitisinfektionen. - Folgt einem zielgerichteten Ansatz und greift dabei auf aktuelle Literatur und Expertenmeinungen zurück. Die 2. Auflage von Clinical Dilemmas in Viral Liver Disease ist ein Muss für Hepatologen, Gastroenterologen, Transplantationschirurgen, Virologen und medizinisches Fachpersonal, das Patienten mit Lebererkrankungen betreut.

Author: Tarek I. Hassanein
Publisher: Elsevier Health Sciences
ISBN: 0323682758
Category : Medical
Languages : en
Pages :

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Book Description
In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Tarek Hassanein has assembled top experts in hepatology to bring current information on the topic of Hepatitis B Virus. The issue provides the most current information on the prevention and care of infected patients. Specific articles are devoted to the following topics: Global perspective on HBV infections in the era of effective vaccines; Understanding the natural history of HBV infection and the new definitions of cure and the endpoints of clinical trials; HBV/HCV coinfection in the era of HCV-DAAs; Antiretroviral effects on HBV/HIV coinfection and the natural history of liver disease; Impact of HBV infection on HCC and liver transplantation; HBV in pregnant women and their infants; WHO guidelines for prevention, care and treatment of individuals infected with HBV: A US perspective; Reconciling the difference between the major HBV treatment guidelines: AASLD, EASL, APASL; HBV/HDV coinfection: A challenge for therapeutics; and The effects of hepatic steatosis on the natural history of HBV infection. Readers will come away with the current information they need to manage patient outcomes.

Author: Naglaa Allam
Publisher: BoD – Books on Demand
ISBN: 9535129937
Category : Medical
Languages : en
Pages : 408

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Book Description
As in many areas of medicine, treatment of viral hepatitis has seen an acceleration of change driven by new therapies and evolving technology. Thanks to the direct-acting antiviral agents (DAAs), the era of HCV eradication and cure has begun. As regards to hepatitis B therapy, potent antiviral drugs for suppression of viral replication are available, new research activities to enhance eradication are visible, and these may influence clinical practice in the coming years. This book covers the latest advances in hepatitis C and hepatitis B therapeutics as well as the emerging and investigational treatment strategies. "Advances in Treatment of Hepatitis C and Hepatitis B" book is an up-to-date source of information for physicians, residents, and advanced medical students seeking a broader understanding of treatment of viral hepatitis. The authors of the chapters come from many eminent centers around the world and are experts in their respective fields.

Author: Ira M. Jacobson
Publisher: Saunders
ISBN: 9781416050513
Category : Hepatitis B virus
Languages : en
Pages : 0

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Book Description
Hepatitis B continues to be a worldwide public health problem of major proportions, with over 10% of people in heavily populated endemic areas being chronic carriers of the virus. Enormous strides have been made in understanding the biology of HBV and in management. Overwhelming evidence demonstrates that long-term suppression of viral replication may prevent the dreaded long-term outcomes of this disease. Increasing numbers of drugs that can achieve this goal, without the high risk of emergent viral resistance that characterized treatment as recently as 5 years ago, are available and more will follow, but controversies abound about the most effective manner in which to use these agents and about which patients should be treated. Many experts believe we are moving into an era in which the spectrum of patients who we consider treatment candidates is expanding. A volume on our present understanding about the biology and immunology of HBV, along with a critical analysis of the complex therapeutic issues is most timely.